Results 271 to 280 of about 22,642,428 (383)

High expression of PLA2G2A in fibroblasts plays a crucial role in the early progression of carotid atherosclerosis. [PDF]

J Transl Med
Wang X, Li S, Liu C, Zhao J, Ren G, Zhang F, Liu X, Cao S, Xu Y, Xia Z, Xia Z.   +10 more
europepmc   +1 more source

Regulation of phospholipase A2 activity by different lipid-water interfaces.

, 1977
Arend J. Slotboom, M C van Dam-Mieras, Gerard H. De Haas   +2 more
openalex   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

The FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi, Lisa Nagase, Shun Kageyama, Hirotaka Kanoh, Masashi Oshima, Aki Ogawa‐Iio, Yoshiki Ikeda, Yuki Fujii, Sei Kondo, Natsuki Osaka, Takeshi Masuda, Tsukasa Ishihara, Yoshikazu Nakamura, Yoshihisa Hirota, Takehiko Sasaki, Toshiya Senda, Atsuo T. Sasaki   +16 more
wiley   +1 more source

Contribution of individual phospholipase A₂ enzymes to the cleavage of oxidized phospholipids in human blood plasma. [PDF]

J Lipid Res
Jokesch P, Oskolkova O, Fedorova M, Gesslbauer B, Bochkov V.   +4 more
europepmc   +1 more source

Fatty‐acid amide hydrolase inhibition mitigates Alzheimer's disease progression in mouse models of amyloidosis

The FEBS Journal, EarlyView.
Enhancing endocannabinoid signaling by targeting FAAH effectively mitigates cognitive deficits, reduces amyloid pathology, and modulates neuroinflammatory responses in a preclinical model of Alzheimer's disease. This effect is potentially mediated by attenuating the Aβ‐induced overexpression of the Bace1 gene through CB1‐dependent hypermethylation of ...
Sergio Oddi, Lucia Scipioni, Antonio Totaro, Giacomo Giacovazzo, Francesca Ciaramellano, Daniel Tortolani, Alessandro Leuti, Rita Businaro, Federica Armeli, Andras Bilkei‐Gorzo, Roberto Coccurello, Andreas Zimmer, Mauro Maccarrone   +12 more
wiley   +1 more source

Animal Venoms and Their Components: Molecular Mechanisms of Action V 2.0. [PDF]

Toxins (Basel)
Utkin Y.
europepmc   +1 more source

Phosphatidic acid induces cytoskeletal rearrangements through the Src‐FAK‐RhoA/ROCK signaling pathway during decidualization

The FEBS Journal, EarlyView.
Decidualization is the process by which human endometrial stromal cells undergo morphological and functional changes to prepare the uterus for embryo implantation and support pregnancy. Our study identifies the phosphatidic acid‐Src‐FAK‐RhoA/ROCK signaling pathway as a critical regulator of the cytoskeletal alterations required for this transformation.
Hyeon‐Jeong Jun, So Young Lee, Shin‐Young Park, Joong Sub Choi, Mee‐Sup Yoon, Joong‐Soo Han   +5 more
wiley   +1 more source

Safety evaluation of the food enzyme phospholipase A1 from the genetically modified <i>Trichoderma reesei</i> strain DP-Nzk98. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Sramkova M, Van Loveren H, Vernis L, Andryszkiewicz M, Cavanna D, Kovalkovičová N, Liu Y.   +17 more
europepmc   +1 more source

Formation of Phospholipase C and Theta-haemolysin in Pre-reduced Media in Batch and Continuous Culture of Clostridium perfringens Type A

, 1974
C. E. Nord, R. Möllby, C. J. Smyth, Torkel Wadström   +3 more
openalex   +1 more source

Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley   +1 more source