Results 291 to 300 of about 22,642,428 (383)

Neutrophils in the Bone Marrow Express DEC205, Guiding Their Migration to Inflamed Tissues

Immunology, EarlyView.
In bone marrow, immature neutrophils express high levels of DEC205, necessary to mediate migration through endothelial cell layers in vitro and in vivo. During maturation and migration to peripheral tissues, expression of DEC205 is downregulated. Thus, expression of DEC205 inversely correlates with the maturation of neutrophils and is involved in ...
Shiying Jin, Xuan Lei, Sonali Singh, Alexander Enk, Karsten Mahnke   +4 more
wiley   +1 more source

Toxins from Animal Venom-A Rich Source of Active Compounds with High Pharmacological Potential. [PDF]

Toxins (Basel)
Lyukmanova EN, Shenkarev ZO.
europepmc   +1 more source

Research Review: What we have learned about the endocannabinoid system in developmental psychopathology

Journal of Child Psychology and Psychiatry, EarlyView.
Background The endocannabinoid (eCB) system, the primary target of cannabis, has gained significant attention as a potential novel therapeutic approach for treating a range of psychiatric disorders characterized by dysregulation of stress, emotion, and social behavior.
Ryann C. Tansey, Marc D. Ferger, Hilary A. Marusak, Leah M. Mayo   +3 more
wiley   +1 more source

Molecular Evolution and Adaptation Strategies in Marine Ciliates: An Inspiration for Cold-Adapted Enzyme Engineering and Drug Binding Analysis. [PDF]

Mar Drugs
Pucciarelli S, Mozzicafreddo M, Vassallo A, Piersanti A, Miceli C.   +4 more
europepmc   +1 more source

Effect of Phospholipase C Hydrolysis of Membrane Phospholipids on Membranous Enzymes

, 1972
Richard D. Mavis, Robert M. Bell, P. Roy Vagelos   +2 more
openalex   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Editorial: Direct modulation of ion channels by G-proteins. [PDF]

Front Physiol
Yakubovich D.
europepmc   +1 more source

Unveiling the Evolutionary History of European Vipers and Their Venoms From a Multi‐Omic Approach

Molecular Ecology, EarlyView.
ABSTRACT Snake genomes attract significant attention from multiple disciplines, including medicine, drug bioprospection, and evolutionary biology. However, genomic research within the Viperidae family has mostly focused on the subfamily Crotalinae, while the true vipers (Viperinae) have largely been overlooked.
Adrián Talavera, Marc Palmada‐Flores, Fernando Martínez‐Freiría, Gabriel Mochales‐Riaño, Bernat Burriel‐Carranza, Maria Estarellas, Daniel Fernández‐Guiberteau, Álvaro Camina, Sylvain Ursenbacher, Judit Vörös, Bálint Halpern, Davinia Pla, Juan José Calvete, Alexander S. Mikheyev, Tomàs Marquès‐Bonet, Salvador Carranza   +15 more
wiley   +1 more source

Exploring the Venom Gland Transcriptome of <i>Bothrops asper</i> and <i>Bothrops jararaca</i>: De Novo Assembly and Analysis of Novel Toxic Proteins. [PDF]

Toxins (Basel)
Espín-Angulo J, Vela D.
europepmc   +1 more source

Central mechanisms of emesis: A role for GDF15

Neurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
Abstract Background Nausea and emesis are ubiquitously reported medical conditions and often present as treatment side effects along with polymorbidities contributing to detrimental life‐threatening outcomes, such as poor nutrition, lower quality of life, and unfavorable patient prognosis.
Tito Borner, Allison M. Pataro, Bart C. De Jonghe   +2 more
wiley   +1 more source