Results 341 to 350 of about 22,290,738 (402)

Phospholipase-A activity of mammalian tissues

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1965
Abstract 1. 1.The phospholipase-A (phosphatide acyl-hydrolase, EC 3.1.1.4) activity of extracts of a number of different rat tissues has been determined by estimating the decline in the concentration of lecithin together with the increase in the concentration both of fatty acids and of lysolecithin, that occurs when the extract is incubated with ...
J J, GALLAI-HATCHARD, R H, THOMPSON
openaire   +2 more sources

Serum phospholipase A in hematological diseases

Klinische Wochenschrift, 1989
Inflammatory cells, e.g., neutrophils, monocytes, and macrophages are presumed to be a source of circulating phospholipase A in nonpancreatic diseases. Therefore, we investigated in a preliminary study whether serum phospholipase A activity is related to leukocyte counts in 43 patients with hematological diseases.
R T, Hiefinger, W G, Guder, G E, Hoffmann   +2 more
openaire   +2 more sources

ExoU is a potent intracellular phospholipase

Molecular Microbiology, 2004
SummaryThe combination of a large genome encoding metabolic versatility and conserved secreted virulence determinants makes Pseudomonas aeruginosa a model pathogen that can be used to study host–parasite interactions in many eukaryotic hosts. One of the virulence regulons that likely plays a role in the ability of P.
Hiromi, Sato, Dara W, Frank
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Distribution of membrane-confined phospholipases A in the rat hepatocyte.

Biochimica et Biophysica Acta, 1972
J. Nachbaur, A. Colbeau, P. Vignais
semanticscholar   +1 more source

A rapid and simple phospholipase A assay

Toxicon, 1966
Abstract A simple and rapid method for the assay of phospholipase A was developed. As a substrate fresh egg yolk is used which is hydrolyzed by snake venom phospholipase A at a 10–20 × faster rate than pure lecithin. The released fatty acids, after extraction with appropriate solvents are titrated automatically.
openaire   +2 more sources

A Phospholipase with a Novel Catalytic Triad

Angewandte Chemie International Edition, 1999
Catalytic triads are a long-standing paradigm of enzyme catalysis. By using a "matched mutation" approach, that is, a simultaneous exchange of the protein (through mutagenesis) and the substrate (through substitution of oxygen atoms by sulfur atoms) followed by enzyme kinetic analysis, a novel catalytic triad (see figure) with an unusual amino acid ...
openaire   +2 more sources

Studies on the mechanism of drug-induced lipidosis. Cationic amphiphilic drug inhibition of lysosomal phospholipases A and C.

Biochemical Pharmacology, 1981
K. Hostetler, Yuji Matsuzawa
semanticscholar   +1 more source

Isolation and characterization of three phospholipases A from the crotoxin complex.

Biochimica et Biophysica Acta, 1975
H. Breithaupt, T. Satoh, J. Lang
semanticscholar   +1 more source

What can venom phospholipases A(2) tell us about the functional diversity of mammalian secreted phospholipases A(2)?

Biochimie, 2000
E. Valentin, G. Lambeau
semanticscholar   +1 more source

Transcriptional regulation of inflammatory secreted phospholipases A(2).

Biochimica et Biophysica Acta, 2000
Marise Andréani, J. Olivier, Francis Berenbaum, M. Raymondjean, G. Béréziat   +4 more
semanticscholar   +1 more source