Results 11 to 20 of about 6,180 (194)

Reversal of mitochondrial proteomic loss in Type 1 diabetic heart with overexpression of phospholipid hydroperoxide glutathione peroxidase.

Am J Physiol Regul Integr Comp Physiol, 2013
Baseler WA, Dabkowski ER, Jagannathan R, Thapa D, Nichols CE, Shepherd DL, Croston TL, Powell M, Razunguzwa TT, Lewis SE, Schnell DM, Hollander JM.   +11 more
europepmc   +3 more sources

Proteomic and metabolomic analysis of ageing beef exudate to determine that iron metabolism enhances muscle protein and lipid oxidation

Food Chemistry: X, 2023
The study aimed to assess differences in proteomic and metabolite profiles in ageing (1, 2, 4, and 6 days at 4 °C) beef exudates and determine their relationship with beef muscle iron metabolism and oxidation.
Jun Liu, Cuili Pan, Hui Yue, He Li, Dunhua Liu, Ziying Hu, Yuanliang Hu, Xiang Yu, Weiwei Dong, Yanli Feng   +9 more
doaj   +1 more source

Eukaryotic Initiation Factor 4A-3: A Review of Its Physiological Role and Involvement in Oncogenesis

Frontiers in Oncology, 2021
EIF4A3, a member of the DEAD-box protein family, is a nuclear matrix protein and a core component of the exon junction complex (EJC). Under physiological conditions, EIF4A3 participates in post-transcriptional gene regulation by promoting EJC control of ...
Jiazhou Ye, Xiaomin She, Ziyu Liu, Ziqin He, Xing Gao, Lu Lu, Rong Liang, Yan Lin   +7 more
doaj   +1 more source

Reactivity of mitochondrial peroxiredoxins with biological hydroperoxides

Redox Biochemistry and Chemistry, 2023
Mitochondria are main sources of biological hydroperoxides, including hydrogen peroxide, peroxynitrite and various organic hydroperoxides. Most of these species are involved in the regulation of cellular functions when formed at low, physiological levels.
Madia Trujillo, Lucía Piacenza, Rafael Radi   +2 more
doaj   +1 more source

Phospholipid hydroperoxide glutathione peroxidase activity of human glutathione transferases [PDF]

Biochemical Journal, 1998
Human glutathione transferases (GSTs) from Alpha (A), Mu (M) and Theta (T) classes exhibited glutathione peroxidase activity towards phospholipid hydroperoxide. The specific activities are in the order: GST A1-1 > GST T1-1 > GST M1-1 > GST A2-2 > GST A4-4.
R, Hurst, Y, Bao, P, Jemth, B, Mannervik, G, Williamson   +4 more
openaire   +2 more sources

Metabolism of hydroperoxy-phospholipids in human hepatoma HepG2 cells

Journal of Lipid Research, 1996
Two enzymatic mechanisms have been proposed for the metabolism of hydroperoxy-phospholipids: i) the combined action of phospholipase A2 and glutathione peroxidase, and/or ii) direct enzymatic reduction.
Y Bao, G Williamson
doaj   +1 more source

Saccharomyces cerevisiae Expresses Three Phospholipid Hydroperoxide Glutathione Peroxidases [PDF]

Journal of Biological Chemistry, 2001
The GPX1, GPX2, and GPX3 genes of Saccharomyces cerevisiae have been reported previously to encode glutathione peroxidases (GPxs). We re-examined the sequence alignments of these proteins with GPxs from higher eukaryotes. Sequence identities, particularly with phospholipid hydroperoxide glutathione peroxidases (PHGPxs), were enhanced markedly by ...
A M, Avery, S V, Avery
openaire   +2 more sources

Exogenous salicylic acid enhances wheat drought tolerance by influence on the expression of genes related to ascorbate-glutathione cycle

Biologia Plantarum, 2013
Treatment with 0.5 mM salicylic acid (SA) significantly alleviated growth inhibition induced by drought in wheat seedlings, manifested by less decreassed fresh mass, dry mass, plant height, root length, and less increased lipid peroxidation.
G. Z. Kang, G. Z. Li, G. Q. Liu, W. Xu, X. Q. Peng, C. Y. Wang, Y. J. Zhu, T. C. Guo   +7 more
doaj   +1 more source

Glutathione metabolism in Cryptocaryon irritans involved in defense against oxidative stress induced by zinc ions

Parasites & Vectors, 2022
Background Cryptocaryon irritans is a fatal parasite for marine teleosts and causes severe economic loss for aquaculture. Galvanized materials have shown efficacy in controlling this parasite infestation through the release of zinc ions to induce ...
Zhi-Hong Zhong, Zhi-Cheng Li, Han Li, Qing-Kai Guo, Chen-Xi Wang, Ji-Zhen Cao, An-Xing Li   +6 more
doaj   +1 more source

Red blood cells contain enzymatically active GPx4 whose abundance anticorrelates with hemolysis during blood bank storage

Redox Biology, 2021
The antioxidant function of the phospholipid hydroperoxide glutathione peroxidase (GPx4) is vital for the homeostasis of many cell types, from neoplastic cells to normal erythroid precursors.
Jeffrey M. Stolwijk, Jonathan A. Stefely, Mike T. Veling, Thomas J. van ‘t Erve, Brett A. Wagner, Thomas J. Raife, Garry R. Buettner   +6 more
doaj   +1 more source