Results 121 to 130 of about 225,303 (298)
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang+4 more
wiley +1 more source
Preferential Membrane Remodeling on Curved Biointerfaces Induced by Conjugated Oligoelectrolyte
This study explores how membrane shape influences the interaction of conjugated oligoelectrolytes (COEs) with lipid bilayers. Using a curved biointerface composed of nanobar arrays and supported lipid bilayers, it is revealed that COE intercalation preferentially remodels curved regions, forming distinct structures. These findings highlight the role of
Xinwen Miao+7 more
wiley +1 more source
THE IN VITRO FORMATION OF PHOSPHOLIPID BY BRAIN AND NERVE WITH RADIOACTIVE PHOSPHORUS AS INDICATOR
B.A. Fries+2 more
openalex +1 more source
GMO cubosomes and DOPE hexosomes interact differently with lipid membranes: cubosomes exchange lipid molecules with the membranes, destabilizing them when the membranes do not contain cholesterol. Hexosomes interact more gently with membranes and tend to fuse and incorporate into them.
Mario Campana+4 more
wiley +1 more source
THE FORMATION OF PHOSPHOLIPID BY THE HEPATECTOMIZED DOG AS MEASURED WITH RADIOACTIVE PHOSPHORUS
M. C. Fishler+3 more
openalex +1 more source
On the Intestinal Absorption of Phospholipids in the Rat. [PDF]
Rolf Blomstrand+3 more
openalex +1 more source
Nanoinjection Platform for Drug Delivery in Breast Cancer Therapeutics
A schematic shows Nanoarchaeosomes loaded with doxorubicin (NAD) delivered via silicon nanotubes (SiNTs) into MCF‐7 cells, triggering apoptosis and necrosis. Released doxorubicin generates ROS, disrupts mitochondria, and intercalates DNA. This dual‐action nanoinjection enhances cytotoxicity and improves breast cancer therapy efficacy.
Kaviya Vijayalakshmi Babunagappan+8 more
wiley +1 more source
Flow Analysis in Pathological Microvascular Models by Ultrasound Localization Microscopy
This study presents a new platform combining ultrasound localization microscopy with biomimetic gelatin phantoms to analyze flow dynamics in small vessels with narrowing or obstructions. Using microbubble tracking, the method enables high‐resolution velocity mapping in 100–500 µm channels, revealing flow changes in pathological microvascular conditions
Yarin Gershman+3 more
wiley +1 more source