Results 141 to 150 of about 225,303 (298)
STUDIES ON THE MODE OF ACTION OF CLOFIBRATE: EFFECTS ON HORMONE‐INDUCED CHANGES IN PLASMA FREE FATTY ACIDS, CHOLESTEROL, PHOSPHOLIPIDS AND TOTAL ESTERIFIED FATTY ACIDS IN RATS AND DOGS [PDF]
A. M. Barrett, John M. Thorp
openalex +1 more source
Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji+12 more
wiley +1 more source
Phospholipids from Bacillus stearothermophilus [PDF]
George L. Card+2 more
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This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren+11 more
wiley +1 more source
Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5
Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao+9 more
wiley +1 more source
Membrane-Embedded Anti-Cancer Peptide Causes a Minimal Structural Perturbation That Is Sufficient to Enhance Phospholipid Flip-Flop and Charge Permeation Rates. [PDF]
Cardenas AE, Elber R.
europepmc +1 more source
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu+6 more
wiley +1 more source
The oily nucleus- role of phospholipids in genome biology: membrane-directed roles and signaling in the nucleoplasm. [PDF]
Umair Z, Nawaz Z, Hasnain S, Fischle W.
europepmc +1 more source