Results 191 to 200 of about 300,277 (292)

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Quantifying the Activation Barrier for Phospholipid Monolayer Fusion Governing Lipid Droplet Coalescence. [PDF]

Int J Mol Sci
Molotkovsky RJ, Denieva ZG, Senchikhin IN, Urodkova EK, Konarev PV, Peters GS, Galimzyanov TR, Pavlov RV, Bashkirov PV.   +8 more
europepmc   +1 more source

Buttermilk and Krill Oil Phospholipids Improve Hippocampal Insulin Resistance and Synaptic Signaling in Aged Rats

, 2018
João Tomé‐Carneiro, M. Carmen Crespo, Emma Burgos‐Ramos, Cristina Tomás‐Zapico, Alba M. García-Serrano, Pilar Castro‐Gómez, César Venero, Inmaculada Pereda-Pérez, Shishir Baliyan, Azucena Valencia, Javier Fontecha, Alberto Dávalos, Francesco Visioli   +12 more
openalex   +2 more sources

Mechanical effects of the intraarticular administration of high molecular weight hyaluronic acid plus phospholipid on synovial joint lubrication and prevention of articular cartilage degeneration in experimental osteoarthritis [PDF]

, 2003
Tsutomu Kawano, Hiromasa Miura, Taro Mawatari, Taka‐aki Moro‐oka, Yoshitaka NAKANISHI, Hidehiko HIGAKI, Yukihide Iwamoto   +6 more
openalex   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Stocking density modulates tilapia (Oreochromis niloticus) performance and fillet quality through phospholipid remodeling. [PDF]

Sci Rep
Roldi G, Robath S, Porto C, Pilau E, Giaquinto P, Neto JF, Lala B, Mari GC, Santos CT, Anastácio GN, Cangianelli GH, Ferreira AL, Ouros CC, Chavesk GHC, Souza MLR, de Oliveira Marques D, Claudino-Silva SC.   +16 more
europepmc   +1 more source

Phospholipid Scramblase 1 Is Secreted by a Lipid Raft-dependent Pathway and Interacts with the Extracellular Matrix Protein 1 in the Dermal Epidermal Junction Zone of Human Skin

, 2010
J. Merregaert, Johanna Van Langen, Uwe Hansen, Peter Ponsaerts, Abdoelwaheb El Ghalbzouri, Ellen Steenackers, Xaveer Van Ostade, Sandy Sercu   +7 more
openalex   +1 more source

Amino Acid Directed Helical Assemblies of Natural Berberine for Chirality‐Dependent Photodynamic Antibacterial Therapy

Advanced Science, EarlyView.
Helical nanostructures co‐assembled from berberine (BBR) and Fmoc‐Y display supramolecular‐chirality‐dependent photodynamic antibacterial activity. The molecular chirality of Fmoc‐Y organizes achiral BBR into chiral nanofibers, where supramolecular handedness controls bacterial surface adsorption, membrane penetration, intracellular BBR delivery, and ...
Haoqiang Zhao, Jingyi Jiao, Zhixia Wang, Chengyu Shi, Xinran Huang, Yixuan Lin, Haolin Yang, Haimin Lei, Guanghui Ouyang, Minghua Liu   +9 more
wiley   +1 more source

Mass Spectrometry Imaging Elucidates the Precise Localization and Site-Specific Functions of Skin Lipids. [PDF]

Int J Mol Sci
Tokoro S, Ogawa T, Hayashi S, Igawa K.
europepmc   +1 more source

PDIA3 Inhibition Facilitates Sensitivity of IKE‐Induced Ferroptosis via STAT3/LCN2 Axis to Improve Glioblastoma Therapy

Advanced Science, EarlyView.
In this manuscript, protein disulfide isomerase A3 (PDIA3) is identified as a key factor mediating the susceptibility of ferroptosis in GBM. Inhibition of PDIA3 enhances IKE or cystine starvation‐induced ferroptosis in GBM cells by resulting in the accumulation of lipid peroxidation and a reduction in GSH level.
Jie Zhang, Wei Wang, Xin Liu, Peifen Lu, Xinjing Liu, Qiucheng Nie, Siyuan Xin, Hong Li, Donglin Yu, Xinyue Zhang, Kailong Li, Xiaomin Han, Shuping Zhang, Wei Chong, Lili Sun, Wei Li, Tao Xin, Jin Jiao, Qiang Ma, Yiju Wei   +19 more
wiley   +1 more source