Results 211 to 220 of about 447,971 (300)

Multiplexed Tandem Mass Spectrometry Imaging Enables Large‐Scale Isomer Mapping and Annotation in Tissues

Angewandte Chemie, EarlyView.
Parallel mass spectrometry imaging acquires high mass resolution and tandem mass spectrometry images from 108 isolation windows in a single run. Spatial similarity networking clusters product ions by spatial distribution, enabling annotation of isomers and isobars as demonstrated for phospholipids and oxidized cholesterol in mouse and human brain ...
Varun V. Sharma, Gabor Toth, Robert Martinis, Cathrin E. Hansen, Gijs Kooij, Ingela Lanekoff   +5 more
wiley   +2 more sources

Acute graft thrombosis in a patient with factor V Leiden mutation: A case report and review of literature. [PDF]

World J Transplant
Lekehal B, Ait Youssef N, Lekehal M, Jdar A, El Hassani AEA, Belyazid I, Bakkali T, Bounssir A.   +7 more
europepmc   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Development of a High-Throughput UHPLC-DMS-MS/MS Method for Targeted Quantitation of Pertinent Phospholipid Classes in Colon Cancer. [PDF]

Molecules
Wimmer M, Coleman OI, Sorbie A, Haller D, Somoza V, Dunkel A.   +5 more
europepmc   +1 more source

An siRNA targeting <i>S6k1</i> identifies photoreceptor phospholipid metabolism as a contributor to lipid buildup in age-related macular degeneration. [PDF]

Mol Ther Nucleic Acids
Cheng SY, Giguere D, Kim S, Seddon JM, Caiazzi J, Gross K, McHugh N, Echeverria D, Alterman JF, Gray-Edwards H, Benatti HR, Renner L, Woolard H, Stoddard J, McGill TJ, Neuringer M, Brush RS, Agbaga MP, Khvorova A, Punzo C.   +19 more
europepmc   +1 more source

Lipid scavenging by the Lyme disease spirochete Borrelia burgdorferi. [PDF]

PLoS Pathog
Gwynne PJ, Bourgeois JS, Pandit A, Asara JM, Hu LT.   +4 more
europepmc   +1 more source

Polyfluoralkylierte zellpenetrierende Peptid‐Additive verbessern die intrazelluläre Proteinaufnahme durch eine anhaltende und monomere Lipidinteraktion

Angewandte Chemie, EarlyView.
Wir berichten, dass nicht‐zytotoxische, polyfluoralkylierte zellpenetrierende Peptide (CPPs) als CPP‐Additive die intrazelluläre Proteinaufnahme signifikant verbessern, indem sie die Membranverweildauer der CPP‐Additive erhöhen. Durch die Kombination von biophysikalischen Experimenten und Molekulardynamiksimulationen zeigen wir zudem, dass die ...
Sarah Hansen, Hana Zupan, Ferhat Mutlu, Jan Vincent V. Arafiles, Rubén Cruz, Palina Dubatouka, Kenichi Ataka, Martin Lehmann, Bettina G. Keller, Joachim Heberle, Christian P. R. Hackenberger   +10 more
wiley   +1 more source

Correction to "Martini 3 Limitations in Phospholipid Flip-Flop". [PDF]

J Chem Theory Comput
Kroutil O, Bartoš L, Kabelka I, Vácha R.   +3 more
europepmc   +1 more source

Recent Trends in Metabolomics by NMR Spectroscopy

Angewandte Chemie, EarlyView.
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco, Gaia Meoni, Veronica Ghini, Alessia Vignoli, Leonardo Tenori, Paola Turano, Claudio Luchinat   +6 more
wiley   +1 more source