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A Synergistic Genetic Engineering Strategy Induced Triacylglycerol Accumulation in Potato (Solanum tuberosum) Leaf

open access: yesFrontiers in Plant Science, 2020
Potato is the 4th largest staple food in the world currently. As a high biomass crop, potato harbors excellent potential to produce energy-rich compounds such as triacylglycerol as a valuable co-product. We have previously reported that transgenic potato
Xiao-yu Xu   +14 more
doaj   +1 more source

Human Brain Lipidomics: Investigation of Formalin Fixed Brains

open access: yesFrontiers in Molecular Neuroscience, 2022
Human brain lipidomics have elucidated structural lipids and lipid signal transduction pathways in neurologic diseases. Such studies have traditionally sourced tissue exclusively from brain bank biorepositories, however, limited inventories signal that ...
Aaron W. Beger   +5 more
doaj   +1 more source

Deficiency of MGAT2 increases energy expenditure without high-fat feeding and protects genetically obese mice from excessive weight gain

open access: yesJournal of Lipid Research, 2011
Acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) is thought to be crucial for dietary fat absorption. Indeed, mice lacking the enzyme (Mogat2−/−) are resistant to obesity and other metabolic disorders induced by high-fat feeding.
David W. Nelson   +4 more
doaj   +1 more source

Higher Genetically Predicted Triglycerides, LDL, and HDL Increase the Vitamin D Deficiency: A Mendelian Randomization Study

open access: yesFrontiers in Nutrition, 2022
IntroductionIt has been proven that high body mass index (BMI) levels can cause vitamin D deficiency, but the mechanism is still unclear. Therefore, this study attempts to explain this phenomenon from the perspective of blood lipid by using mendelian ...
Zhe Lu, Yang Jiao, Jun Li
doaj   +1 more source

Functional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemia

open access: yesJournal of Lipid Research, 2010
We have shown that expression of apolipoprotein (apo) C-III promotes VLDL secretion from transfected McA-RH7777 cells under lipid-rich conditions. To determine structural elements within apoC-III that confer to this function, we contrasted wild-type apoC-
Meenakshi Sundaram   +10 more
doaj   +1 more source

Thematic review series: Adipocyte Biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis

open access: yesJournal of Lipid Research, 2007
The majority of eukaryotic cells synthesize neutral lipids and package them into cytosolic lipid droplets. In vertebrates, triacylglycerol-rich lipid droplets of adipocytes provide a major energy storage depot for the body, whereas cholesteryl ester-rich
Dawn L. Brasaemle
doaj   +1 more source

Responsibility of regulatory gene expression and repressed protein synthesis for triacylglycerol accumulation on sulfur-starvation in Chlamydomonas reinhardtii

open access: yesFrontiers in Plant Science, 2014
Triacylglycerol (TG) synthesis is induced for energy and carbon storage in algal cells under nitrogen(N)-starved conditions, and helps prevent reactive oxygen species production through fatty acid synthesis that consumes excessive reducing power.
Atsushi eSato   +7 more
doaj   +1 more source

Lipid modulation contributes to heat stress adaptation in peanut

open access: yesFrontiers in Plant Science, 2023
At the cellular level, membrane damage is a fundamental cause of yield loss at high temperatures (HT). We report our investigations on a subset of a peanut (Arachis hypogaea) recombinant inbred line population, demonstrating that the membrane lipid ...
William W. Spivey   +7 more
doaj   +1 more source

No effects of Korean pine nut triacylglycerol on satiety and energy intake

open access: yesNutrition & Metabolism, 2011
Background Triacylglycerols (TAG) have been shown to have potential appetite suppressing effects. This study examined the effects of 3 g and 6 g Korean pine nut triacylglycerols (PinnoThin) on appetite and energy intake. Methods 130 g Isoenergetic yogurt
Verhoef Sanne PM, Westerterp Klaas R
doaj   +1 more source

An engineered lipid remodeling system using a galactolipid synthase promoter during phosphate starvation enhances oil accumulation in plants

open access: yesFrontiers in Plant Science, 2015
Inorganic phosphate (Pi) depletion is a serious problem for plant growth. Membrane lipid remodeling is a defense mechanism that plants use to survive Pi-depleted conditions.
Mie eShimojima   +11 more
doaj   +1 more source

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