Results 31 to 40 of about 113,283 (337)

Sex differences in the association between plasma copeptin and incident type 2 diabetes: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study [PDF]

, 2012
AIMS/HYPOTHESIS: Vasopressin plays a role in osmoregulation, glucose homeostasis and inflammation. Therefore, plasma copeptin, the stable C-terminal portion of the precursor of vasopressin, has strong potential as a biomarker for the cardiometabolic ...
A Abbasi, A Tanoue, A. Abbasi, AD Pradhan, AH Brantsma, B Balkau, B Buijsse, B Thorand, B Thorand, C Herder, CJ Kirk, D. Postmus, E Kajantie, E Meijer, E. Corpeleijn, E. Meijer, EL Ding, G. Navis, GS Collins, H. L. Hillege, HJ Lambers Heerspink, J Struck, J. Struck, JM Halimi, K McGeechan, K Nakamura, LD Simmler, ME Rhodes, MJ Pencina, NG Morgenthaler, NR Cook, NS Stachenfeld, R. O. B. Gans, R. P. Stolk, R. T. Gansevoort, RL Zerbe, S Enhorning, S Enhorning, S Oertelt-Prigione, S Oshikawa, S. J. L. Bakker, SS Bhandari, T Aoyagi, TB Monster, U Saleem, V Salomaa, W Fenske, Y Fujiwara   +47 more
core   +4 more sources

Characterization of key triacylglycerol biosynthesis processes in rhodococci. [PDF]

, 2016
Oleaginous microorganisms have considerable potential for biofuel and commodity chemical production. Under nitrogen-limitation, Rhodococcus jostii RHA1 grown on benzoate, an analog of lignin depolymerization products, accumulated triacylglycerols (TAGs ...
Amara, Sawsan, Diaz-Salazar, Carlos, Eltis, Lindsay D, Liu, Jie, Otani, Hiroshi, Seghezzi, Nicolas   +5 more
core   +2 more sources

Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol

Diabetologia, 2011
Aims/hypothesisType 2 diabetes is regarded as inevitably progressive, with irreversible beta cell failure. The hypothesis was tested that both beta cell failure and insulin resistance can be reversed by dietary restriction of energy intake.MethodsEleven ...
E. Lim, K. Hollingsworth, Benjamin S. Aribisala, M. Chen, J. Mathers, R. Taylor   +5 more
semanticscholar   +1 more source

Diet Induced Obesity Alters Intestinal Cytoplasmic Lipid Droplet Morphology and Proteome in the Postprandial Response to Dietary Fat

Frontiers in Physiology, 2019
Dietary fat absorption by the small intestine is an efficient, multistep process that regulates the uptake and delivery of essential nutrients and energy. Fatty acids taken up by enterocytes, the absorptive cells of the small intestine, are resynthesized
Theresa D’Aquila, Alyssa S. Zembroski, Kimberly K. Buhman   +2 more
doaj   +1 more source

A simple, rapid, and sensitive fluorescence-based method to assess triacylglycerol hydrolase activity

Journal of Lipid Research, 2021
Lipases constitute an important class of water-soluble enzymes that catalyze the hydrolysis of hydrophobic triacylglycerol (TAG). Their enzymatic activity is typically measured using multistep procedures involving isolation and quantification of the ...
Sujith Rajan, Hazel C. de Guzman, Thomas Palaia, Ira J. Goldberg, M. Mahmood Hussain   +4 more
doaj   +1 more source

Insulin resistance in type 1 diabetes: what is ‘double diabetes’ and what are the risks? [PDF]

, 2013
In this review, we explore the concept of ‘double diabetes’, a combination of type 1 diabetes with features of insulin resistance and type 2 diabetes.
A Caixas, AM Taylor, B Conway, B Teupe, B. M. Fisher, BF Voight, CT Prince, D Williams, D Yazici, DB Savage, DM Maahs, DM Maahs, DM Nathan, EA Nikkila, ER Christ, ES Kilpatrick, G Pambianco, G Perseghin, G Perseghin, G Roglic, G Ruotolo, H. M. Colhoun, HM Colhoun, IE Schauer, J Frystyk, J Guy, J Yip, J-L Selam, J. R. Petrie, JA Edge, JB Ferriss, JC Zgibor, JQ Purnell, JQ Purnell, JR Erbey, JR Petrie, JT Lahtela, KJ Nadeau, L Hodson, LM Thorn, M Kacerovsky, MR Taskinen, MR Taskinen, MR Taskinen, N Chaturvedi, N Sattar, N. Sattar, P Nevalainen, P Petruzzo, R Sinha, RA Heptulla, RW James, S Makimattila, S Norbert, S Vella, S. J. Cleland, SC Bain, SD Sibley, SJ Livingstone, SR Vethakkan, The Diabetes Control and Complications Trial Research Group, TJ Orchard, TJ Wilkin   +62 more
core   +3 more sources

Targeting mitochondrial 18 kDa translocator protein (TSPO) regulates macrophage cholesterol efflux and lipid phenotype [PDF]

, 2014
The aim of the present study was to establish mitochondrial cholesterol trafficking 18 kDa translocator protein (TSPO) as a potential therapeutic target, capable of increasing macrophage cholesterol efflux to (apo)lipoprotein acceptors.
Anne-Marie Allen, Annette Graham, Batarseh, Bird, Borthwick, Borthwick, Brown, Dmitrova-Shumkovska, Engel, Falchi, Farke, Feramisco, Fernandez-Hernando, Gallus, Gerrity, Gut, Hebbachi, Janice M. W. Taylor, Kannel, Khan, Lecanu, Madamanchi, Mercer, Ning, Ning, Ogata, Oram, Pandak, Puddu, Pyper, Rae, Ren, Rigamonti, Rone, Rosenson-Schloss, Rupprecht, Schnoor, Schultz, Taylor, Vanhee, Venkateswaran, Wang, Xu, Yelieev, Zeng, Zeng, Zoltan   +46 more
core   +1 more source

Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver

Journal of Lipid Research, 2012
Intrahepatic lipid accumulation is extremely common in obese subjects and is associated with the development of insulin resistance and diabetes. Hepatic diacylglycerol and triacylglycerol synthesis predominantly occurs through acylation of glycerol-3 ...
Angela M. Hall, Kou Kou, Zhouji Chen, Terri A. Pietka, Mrudula Kumar, Kevin M. Korenblat, Kyuha Lee, Kay Ahn, Elisa Fabbrini, Samuel Klein, Bryan Goodwin, Brian N. Finck   +11 more
doaj   +1 more source

Metabolic regulation of triacylglycerol accumulation in the green algae: identification of potential targets for engineering to improve oil yield

Plant Biotechnology Journal, 2016
Summary The great need for more sustainable alternatives to fossil fuels has increased our research interests in algal biofuels. Microalgal cells, characterized by high photosynthetic efficiency and rapid cell division, are an excellent source of neutral
E. C. Gonçalves, A. Wilkie, M. Kirst, B. Rathinasabapathi   +3 more
semanticscholar   +1 more source

Circulating lipids in men with type 2 diabetes following 3 days on a carbohydrate‐free diet versus 3 days of fasting

Physiological Reports, 2020
Objective We have been interested in determining the effects of dietary changes on fuel metabolism and regulation in men with type 2 diabetes mellitus (T2DM).
Frank Q. Nuttall, Rami M. Almokayyad, Mary C. Gannon   +2 more
doaj   +1 more source