Results 31 to 40 of about 51,896 (299)
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source
Simulation of triacylglycerol ion profiles: bioinformatics for interpretation of triacylglycerol biosynthesis [PDF]
Journal of Lipid Research, 2013 Although the synthesis pathways of intracellular triacylglycerol (TAG) species have been well elucidated, assessment of the contribution of an individual pathway to TAG pools in different mammalian organs, particularly under pathophysiological conditions, is difficult, although not impossible.
Rowland H. Han +3 more
openaire +3 more sources
Frontiers in Physiology, 2019 Dietary fat absorption by the small intestine is an efficient, multistep process that regulates the uptake and delivery of essential nutrients and energy. Fatty acids taken up by enterocytes, the absorptive cells of the small intestine, are resynthesized
Theresa D’Aquila +2 more
doaj +1 more source
Journal of Lipid Research, 2021 Lipases constitute an important class of water-soluble enzymes that catalyze the hydrolysis of hydrophobic triacylglycerol (TAG). Their enzymatic activity is typically measured using multistep procedures involving isolation and quantification of the ...
Sujith Rajan +4 more
doaj +1 more source
Perilipin A Increases Triacylglycerol Storage by Decreasing the Rate of Triacylglycerol Hydrolysis [PDF]
Journal of Biological Chemistry, 2000 The perilipins are the most abundant proteins at the surfaces of lipid droplets in adipocytes and are also found in steroidogenic cells. To investigate perilipin function, perilipin A, the predominant isoform, was ectopically expressed in fibroblastic 3T3-L1 pre-adipocytes that normally lack the perilipins.
D L, Brasaemle +5 more
openaire +2 more sources
The contribution of serum triacylglycerol to hepatic triacylglycerol turnover in the starved rat [PDF]
Biochemical Journal, 1978 The present study was undertaken to evaluate quantitatively the turnover of serum triacylglycerol (triglyceride) in the starved rat and to determine whether serum triacylglycerol recycled to liver contributes a significant fraction of the total hepatic triacylglycerol turnover.
E W, Lipkin, C, Cooper, R A, Shipley
openaire +2 more sources
Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver
Journal of Lipid Research, 2012 Intrahepatic lipid accumulation is extremely common in obese subjects and is associated with the development of insulin resistance and diabetes. Hepatic diacylglycerol and triacylglycerol synthesis predominantly occurs through acylation of glycerol-3 ...
Angela M. Hall +11 more
doaj +1 more source
Physiological Reports, 2020 Objective We have been interested in determining the effects of dietary changes on fuel metabolism and regulation in men with type 2 diabetes mellitus (T2DM).
Frank Q. Nuttall +2 more
doaj +1 more source
Chloroplasts Isolation from Chlamydomonas reinhardtii under Nitrogen Stress
Frontiers in Plant Science, 2017 Triacylglycerols are produced in abundance through chloroplast and endoplasmic reticulum pathways in some microalgae exposed to stress, though the relative contribution of either pathway remains elusive.
Miao Yang +11 more
doaj +1 more source
Biomolecules, 2022 Innate immune cells such as monocytes and macrophages contain high levels of arachidonic acid (AA), part of which can be mobilized during cellular activation for the formation of a vast array of bioactive oxygenated metabolites. Monocytes and macrophages
Miguel A. Bermúdez +3 more
doaj +1 more source