Results 251 to 260 of about 498,126 (336)

Fabrication, Characterization, and Transcriptomic Analysis of Oregano Essential Oil Liposomes for Enhanced Antibacterial Activity and Sustained Release. [PDF]

Foods
Wang Z, Bao Y, Qiu J, Li S, Chen H, Li C.   +5 more
europepmc   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

Molecular mechanisms of CBASS phospholipase effector CapV mediated membrane disruption. [PDF]

Nat Commun
Kong J, Wu W, Ke S, Zhou Z, Xia S, Chen J, Zhu R, Hou Y, Makanyire T, Shan X, Zhuo Z, Li K, Shen H, Yang P, Huang P, Liu J, Li J, Sun X, Dong J, Sun H, Chen M, Lu M, Li Z, Xiao Y.   +23 more
europepmc   +1 more source

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

Advanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen, Yahui Gao, Yulin Wang, Ting Lei, Zheng Qu, Yuhan An, Jiaxu Fu, Xin Li, Fangjun Liu, Yan Li   +9 more
wiley   +1 more source

Downregulation of PCYT2 by increased portal pressure safeguards liver regeneration after partial hepatectomy. [PDF]

Theranostics
Pu G, Song Y, Li Q, Duan J, Wang G, Xiu W, Xu J, Zhao X, Dong W, Lan T, Ai R, Zhang J, Sun W, Kong D, Zhu Y, Zhang X, Liu Y, Wang C.   +17 more
europepmc   +1 more source

Endothelial Cell‐Based Vascular Bandages for Blood–Brain Barrier Repair and Targeted siRNA Delivery

Advanced Science, EarlyView.
mECs restore blood–brain barrier function after cerebral ischemia–reperfusion by simultaneously targeting, supporting, and regulating the damaged vasculature. mECs home to injured cerebral vessels through interactions with highly expressed VLA‐4, reinforce endothelial integrity by forming new junctions, and, upon OGD‐SN treatment, acquire enhanced ...
Yaosheng Li, Yunfei Dong, Yaode He, Juanjuan Zheng, Hui Liu, Lu Li, Xiaoxu Hao, Yanli Zhao, Zefeng Yang, Yuankai Sun, Zhiwei Du, Bo Zhao, Weihang Zhou, Honghui Wu, Tianyuan Zhang, Jiahe Wu, Xiangrui Liu, Xianzhen Yin, Zhicai Chen, Rui Xue, Min Lou, Zhen Gu, Xinchi Jiang, Jianqing Gao   +23 more
wiley   +1 more source

Cerebral phosphorus metabolite as imaging biomarkers in Alzheimer's disease: a ³¹P magnetic resonance spectroscopy study. [PDF]

Neuroimage Clin
Zhao S, Dong Y, Jiang B, Bai Y, Wei W, Wu Y, Li C, Chen J, Wang M.   +8 more
europepmc   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Optimizing Membrane Composition With C15 and Choline: A Novel Hypothesis to Mitigate Cancer Risk. [PDF]

Cureus
Mercola J.
europepmc   +1 more source

Differential effects of human SP-A1 and SP-A2 variants on phospholipid monolayers containing surfactant protein B

, 2007
Guirong Wang, Svetla G. Taneva, Kevin M. W. Keough, Joanna Floros   +3 more
openalex   +1 more source