Results 191 to 200 of about 368,892 (358)

Cholesterol, triglyceride, and phospholipid content of intima, media, and atherosclerotic fatty streak in human thoracic aorta. [PDF]

, 1966
William Insull, Glenn E. Bartsch
openalex   +1 more source

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

Advanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen, Jianqiang Yang, David O. Popoola, Fan Yang, Yajie Liu, Dongsheng Wang, Zhaohui S. Qin, Zhengjia Chen, Nabil F. Saba, Zhuo G. Chen, Yamin Li, Yong Teng   +11 more
wiley   +1 more source

Phospholipid-Cholesterol Membrane Model [PDF]

, 1962
Julian M. Tobias, D. Agin, Raymond Pawlowski   +2 more
openalex   +1 more source

Targeted Dual‐Responsive Liposomes Co‐Deliver Jolkinolide B and Ce6 to Synergistically Enhance the Photodynamic/Immunotherapy Efficacy in Gastric Cancer through the PANoptosis Pathway

Advanced Science, EarlyView.
Schematic model of CJP–TiN liposomes for gastric cancer (GC) treatment. Internalizing RGD peptide (iRGD) targets tumor cells, while Chlorin e6 (Ce6) generates reactive oxygen species (ROS). Jolkinolide B (JB) activates the PANoptosis pathway via caspase‐8, enhancing GC cell death and immune response, transforming “cold tumors” into “hot tumors” by ...
Chenhui Ma, Lei Gao, Kewei Song, Baohong Gu, Bofang Wang, Yang Yu, Xueyan Wang, Xuemei Li, Jike Hu, Weigao Pu, Yunpeng Wang, Na Wang, Dedai Lu, Zhijian Han, Hao Chen   +14 more
wiley   +1 more source

Phosphatidylthreonine is a procoagulant lipid detected in human blood and elevated in coronary artery disease

Journal of Lipid Research
Aminophospholipids (aPL) such as phosphatidylserine are essential for supporting the activity of coagulation factors, circulating platelets, and blood cells.
Ali A. Hajeyah, Majd B. Protty, Divyani Paul, Daniela Costa, Nader Omidvar, Bethan Morgan, Yugo Iwasaki, Beth McGill, P. Vincent Jenkins, Zaheer Yousef, Keith Allen-Redpath, Shin Soyama, Anirban Choudhury, Rito Mitra, Parveen Yaqoob, James H. Morrissey, Peter W. Collins, Valerie B. O'Donnell   +17 more
doaj  

From experimental clues to theoretical modeling: Evolution associated with the membrane-takeover at an early stage of life. [PDF]

PLoS Comput Biol
Ma W, Yu C.
europepmc   +1 more source

EBBP‐Mediated Integrated Stress Response Attenuates Anthracycline‐Induced Cardiotoxicity by Inhibiting the Ferroptosis of Cardiomyocytes

Advanced Science, EarlyView.
EBBP expression is significantly upregulated in DOX‐treated cardiomyocytes. Mechanistically, EBBP interacts with GRP78 to mediate K63‐linked ubiquitination, thereby attenuating the inhibitory GRP78‐PERK interaction and triggering activation of the PERK‐mediated integrated stress response (ISR).
Zilong Chen, Can Chen, Yichen Wu, Yinxue Xia, Ruijie Luo, Jiangcheng Shu, Long Chen, Zhaohui Wang, Cheng Wang, Kai Huang   +9 more
wiley   +1 more source

A New Approach to Detect and Semi-quantify All Molecular Species and Classes of Anionic Phospholipids Simultaneously in Plant Samples. [PDF]

Bio Protoc
Genva M, Mirande-Bret C, Fouillen L.
europepmc   +1 more source

A Study of the Effect of Nordihydroguaiaretic Acid on the Oxygen Absorption of the Phospholipid Fraction of Milk. I. The Effect of Concentration of Antioxidant

, 1951
J.W. Stull, E.O. Herreid, P.H. Tracy
openalex   +1 more source

Phospholipids and their metabolism. [PDF]

Journal of Clinical Pathology, 1973
openaire   +3 more sources