Ten years ago, describing what is new in phospholipid signaling in ten pages of Cell would have been easy; it would have been essentially a summary of the phospho-inositidase C (PIC) story: phosphatidylinositol(4,5)bisphos-phate (Ptdlns(4,5)P2) hydrolysis to inositiol(1,4,5)trisphos-phate (Ins(1",4,5)P3), with the synergistic action of Ca 2÷(mobilized ...
Divecha, Nullin, Irvine, Robin F.
openaire +3 more sources
Determination of Phospholipids in Antarctic Krill by Hydrophilic Interaction Ultra-high Performance Liquid Chromatography-Tandem Mass Spectrometry Using TiO2/KCC-1 Solid Phase Extraction [PDF]
Phosphatidylcholine (PC), phosphatidyl ethanolamine (PE), phosphatidylserine (PS), and phosphatidylinositol (PI) are the four major phospholipids in Antarctic krill.
ZHANG Xintong, TANG Guangzhi, SHEN Qing, LEI Min, TAN Shuping, LIN Biling, ZHOU Ruiqi, LIANG Xiubi, GUO Lianxian, LI Linqiu
doaj +1 more source
Research Advances in Regulatory Effect of Phospholipids on Meat Quality [PDF]
Phospholipids, a class of polar lipids with complex structure and multiple functions, are composed of glycerophospholipids and sphingomyelins. As an important component of cell membranes, phospholipids are involved in many physiological activities, such ...
ZHANG Kaihua, ZANG Mingwu, Wang Shouwei, ZHANG Zheqi, LI Dan, LI Xiaoman, HAO Rui
doaj +1 more source
Substrate-Specific Inhibition Constants for Phospholipase A2 Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics. [PDF]
Assaying lipolytic enzymes is extremely challenging because they act on water-insoluble lipid substrates, which are normally components of micelles, vesicles, and cellular membranes.
Armando, Aaron+2 more
core +6 more sources
A minimal biochemical route towards de novo formation of synthetic phospholipid membranes. [PDF]
All living cells consist of membrane compartments, which are mainly composed of phospholipids. Phospholipid synthesis is catalyzed by membrane-bound enzymes, which themselves require pre-existing membranes for function.
Bhattacharya, Ahanjit+3 more
core +2 more sources
Effect of dipolar-angle on phospholipid assembly [PDF]
We report the effect of lipid head-group dipole orientation on phase behaviour of phospholipid assembly. The work explains molecular-scale mechanism of ion-lipid, anesthetic-lipid interactions where reorientation of dipoles play important role in membrane potential modification. Molecular Dynamics simulations are performed to analyse structure-property
arxiv +1 more source
Three-year tracking of fatty acid composition of plasma phospholipids in healthy children [PDF]
Objectives: The fatty acid composition of plasma phospholipids reflects the dietary fatty acid intake as well as endogenous turnover. We aimed at investigating the potential tracking of plasma phospholipid fatty acid composition in children that ...
Andersson A+35 more
core +1 more source
Opsin Is a Phospholipid Flippase [PDF]
Polar lipids must flip-flop rapidly across biological membranes to sustain cellular life [1, 2], but flipping is energetically costly [3] and its intrinsic rate is low. To overcome this problem, cells have membrane proteins that function as lipid transporters (flippases) to accelerate flipping to a physiologically relevant rate.
Sakmar, TP+9 more
openaire +5 more sources
A mesoscale model for quantitative phospholipid monolayer simulations at the air-water interface [PDF]
A mesoscale model with molecular resolutions is presented for the dipalmitoyl-phosphatidylcholine (DPPC) and 1-palmitoyl-2-oleyl-sn-glycero-3-phosphocholine (POPC) monolayer simulations at the air-water interface using many-body dissipative particle dynamics (MDPD).
arxiv
Ice Formation in Model Biological Membranes in the Presence of Cryoprotectors [PDF]
Ice formation in model biological membranes is studied by SAXS and WAXS in the presence of cryoprotectors: dimethyl sulfoxide and glycerol. Three types of phospholipid membranes: DPPC, DMPC, DSPC are chosen for the investigation as well-studied model biological membranes. A special cryostat is used for sample cooling from 14.1C to -55.4C.
arxiv +1 more source