Results 81 to 90 of about 53,922 (240)

An Anticoagulant Coating Based on a Block Phosphocholine Copolymer for Potential Applications in Blood Contact Devices

open access: yesAdvanced Materials Interfaces, EarlyView.
Anticoagulant properties are critical for blood‐compatible materials, and anticoagulant coatings are a common key issue for blood‐contacting medical devices. In this study, a block copolymer poly(2‐methacrylenoxyethyl phosphocholine‐b‐glycidyl) (PMPC‐b‐GMA) is synthesized, using reversible addition‐fragmentation chain transfer polymerization (RAFT) and
Xinli Lu   +6 more
wiley   +1 more source

Phosphorus NMR analysis of phospholipids in detergents.

open access: yesJournal of Lipid Research, 1979
Various detergents can be used to dissolve phospholipids, resulting in very narrow 31PNMR resonances. The resonances are well resolved, allowing identification and quantitative analysis of phospholipids in a mixture.
E London, G W Feigenson
doaj  

Lipid‐Hybrid Multicompartment Membrane Systems for Controlled, Compartmentalized Encapsulant Release

open access: yesAdvanced Materials Interfaces, EarlyView.
Herein a bio‐inspired, lipid‐hybrid‐based multicompartmental material for scalable (milliliter) microencapsulation (20 – 200 µm) and controlled release of aqueous solutions is presented. The multicompartmental architecture provides non‐mixing environments, spatial patterning of encapsulants, and controlled compartmentalized release by surfactant ...
Tsuyoshi Inaba   +3 more
wiley   +1 more source

Equilibrium insertion of nanoscale objects into phospholipid bilayers [PDF]

open access: yesCurrent Nanoscience, 7(5), pp.721-726 (2011), 2011
Certain membrane proteins, peptides, nanoparticles and nanotubes have rigid structure and fixed shape. They are often viewed as spheres and cylinders with certain surface properties. Single Chain Mean Field theory is used to model the equilibrium insertion of nanoscale spheres and rods into the phospholipid bilayer.
arxiv  

Preferential Membrane Remodeling on Curved Biointerfaces Induced by Conjugated Oligoelectrolyte

open access: yesAdvanced Materials Interfaces, EarlyView.
This study explores how membrane shape influences the interaction of conjugated oligoelectrolytes (COEs) with lipid bilayers. Using a curved biointerface composed of nanobar arrays and supported lipid bilayers, it is revealed that COE intercalation preferentially remodels curved regions, forming distinct structures. These findings highlight the role of
Xinwen Miao   +7 more
wiley   +1 more source

Biomimetic Orthogonal Removal of Arylacyl Protecting Groups from the C‐Terminus of Substituted Amino Acids and Oligopeptides via Flavin N(5)‐iminium Covalent Adducts

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Abstract Flavin co‐factors and other flavin derivatives are traditionally associated with one‐ or two‐electron redox reactions. Flavins also form covalent intermediates with a variety of substrates. While extensive attention has focused on reactions at the C(4a) position of the flavin ring, recent interest has shifted toward the dynamic potential of ...
Tetiana Pavlovska   +3 more
wiley   +1 more source

Antibiotic–Polycationic Peptide Conjugation as an Effective Strategy to Overcome Daptomycin Resistance

open access: yesAdvanced Therapeutics, EarlyView.
Antimicrobial resistance necessitates the development of new antibiotics with “resistance‐breaking” properties. In this study, conjugation of polycationic peptides is proven to represent a versatile strategy for the fast and affordable reactivation of daptomycin.
Sari Rasheed   +21 more
wiley   +1 more source

Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors

open access: yesAdvanced Therapeutics, EarlyView.
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe   +4 more
wiley   +1 more source

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