Results 51 to 60 of about 24,745,339 (132)

Orchid genome evolution and trait innovation

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2577-2607, August 2026.
Orchids became one of the world's most diverse plant groups through genome‐driven innovations, unique relationships with fungi and pollinators, and remarkable adaptability. This review explains the origins of orchids and the evolution of their distinctive life forms, flowers, and ecological strategies and highlights promising directions for future ...
Meng‐Yao Zeng, Cheng‐Yuan Zhou, Linying Wang, Jie Gao, Weilun Yin, Dong‐Hui Peng, Siren Lan, Feng‐Xi Yang, Zhong‐Jian Liu   +8 more
wiley   +1 more source

Phosphomannomutase deficiency (PMM2-CDG): Ataxia and cerebellar assessment [PDF]

, 2015
Background: Phosphomannomutase deficiency (PMM2-CDG) is the most frequent congenital disorder of glycosylation. The cerebellum is nearly always affected in PMM2-CDG patients, a cerebellar atrophy progression is observed, and cerebellar dysfunction is ...
Pérez, Belén, Felipe, Ana, Belén Pérez, Víctor de Diego, Artuch, Rafael, Laura Gort, Jaeken, Jaak, Pérez-Cerdá, Celia, Girós, Marisa, Vall d'Hebron Institut de Recerca (VHIR), Velázquez, Ramón, Velázquez-Fragua, Ramón, Artuch, R., Bernabé Robles, Pérez González, María Belén, Ana Felipe, O'Callaghan, M. Mar, O'Callaghan, Maria del Mar, Briones, Paz, Poo, M. Pilar, Angels García-Cazorla, Belén Pérez-Dueñas, Cuadras, Cristina, Francisco Carratalá, Paz Briones, Macaya, Alfons, Poo, Pilar, García-Cazorla, Angels, Ramón Velázquez, M. Mar O’Callaghan, Cuadras, Daniel, Muchart, Jordi, Celia Pérez-Cerdá, Jordi Muchart, Boix, Cristina, Carmen Fons, Robles, Bernabé, Marisa Girós, Felipe-Rucián, Ana, Cristina Boix, Carratalá, Francisco, Gort, Laura, Fons, Carmen, Mercedes Serrano, M. Pilar Poo, Jaak Jaeken, Macaya Ruiz, Alfons, Rafael Artuch, Alfons Macaya, Daniel Cuadras, De Diego, Víctor, Pérez-Dueñas, Belén, Universitat Autònoma de Barcelona, Serrano, Mercedes   +53 more
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International clinical guidelines for the management of phosphomannomutase 2-congenital disorders of glycosylation: Diagnosis, treatment and follow up

, 2019
© 2019 SSIEM Phosphomannomutase 2 (PMM2-CDG) is the most common congenital disorder of N-glycosylation and is caused by a deficient PMM2 activity. The clinical presentation and the onset of PMM2-CDG vary among affected individuals ranging from a severe ...
Barone, Rita, de Lonlay, Pascale, Coman, David, Cassiman, David, Jaeken, Jaak, Altassan, Ruqaiah, Corral, Javier, Brasil, Sandra, Cechova, Anna, Correia, Joana, Peanne, Romain, de la Morena-Barrio, Maria Eugenia, Bidet, Muad, Borgel, Delphine, et al.   +14 more
core   +1 more source

Targeted disruption of the mouse phosphomannomutase 2 gene causes early embryonic lethality

, 2006
Thiel C, Lübke T, Matthijs G, von Figura K, Körner C. Targeted disruption of the mouse phosphomannomutase 2 gene causes early embryonic lethality. Molecular and Cellular Biology.
Thiel, Christian, Lübke, Torben ; https://orcid.org/, von Figura, Kurt, Koerner, Christian, Matthijs, Gert, Luebke, Torben, Körner, Christian   +6 more
core   +1 more source

Staphylococcus aureus Extracellular Vesicles Enhance PslE‐Mediated Pathogenesis in Pseudomonas aeruginosa

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
PslE is essential for the ability of S. aureus‐derived extracellular vesicles to enhance P. aeruginosa pathogenicity. ABSTRACT Coinfection of Pseudomonas aeruginosa (P. aeruginosa) and Staphylococcus aureus (S. aureus) is frequently observed. Our previous study demonstrated that S. aureus‐derived extracellular vesicles (SaEVs) promote P.
Phawinee Subsomwong, Rojana Sukchawalit, Naoko Watabe, Akio Nakane, Krisana Asano   +4 more
wiley   +1 more source

A comprehensive update of genotype–phenotype correlations in PMM2-CDG: insights from molecular and structural analyses

Orphanet Journal of Rare Diseases
PMM2-CDG (phosphomannomutase 2-deficiency) is the most prevalent N-glycosylation disorder and results from impairments of PMM2 activity. This disease presents a large variety of pathogenic variants, which cause a wide phenotypical spectrum.
Tiago Oliveira, Ricardo Ferraz, Luísa Azevedo, Dulce Quelhas, João Carneiro, Jaak Jaeken, Sérgio F. Sousa   +6 more
doaj   +1 more source

From Powder to Pathogen: A Systematic Review of Detection, Pathogenicity, and Mitigation of Cronobacter sakazakii in Infant Formula

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Cronobacter sakazakii is an emerging foodborne pathogen that has gained increasing global attention due to its association with severe infections in neonates, particularly meningitis, sepsis, and necrotizing enterocolitis. These infections are often associated with contaminated powdered infant formula (PIF), a nonsterile but commonly used alternative ...
Sutapa Bhowmik, Sangita Ahmed, Fatema Hasan Kaifa, Md. Abdullah Al Safi, Supantha Rivu, Md. Latiful Bari, Md. Aminul Islam, Nayan Chandra Mohanto, Shweta Negi   +8 more
wiley   +1 more source

Identification of genomic regions associated with partial resistance to Aphanomyces root rot in pea

The Plant Genome, Volume 18, Issue 4, December 2025.
Abstract Root rot caused by Aphanomyces euteiches is a major concern in pea (Pisum sativum L.). The lack of other effective control strategies makes crucial the development of resistant varieties. Although partial resistance has been reported, its quantitative inheritance, the association of resistance‐linked genomic regions with unfavorable agronomic ...
Sara Rodriguez‐Mena, Maria Carlota Vaz Patto, Susana Trindade Leitão, Diego Rubiales, Mario González   +4 more
wiley   +1 more source

Unveiling Host Interactions and Evolutionary Constraints of a Novel Bacteriophage Infecting Xanthomonas hortorum pv. vitians

Environmental Microbiology Reports, Volume 17, Issue 6, December 2025.
A transposon insertion sequencing approach revealed that the novel phage ΦXhv‐1 targets Xanthomonas hortorum pv. vitians through LPS O‐antigen recognition. Mutations in LPS conferring phage resistance reduce bacterial motility and virulence, highlighting a trade‐off that may naturally constrain resistance development and support the sustainable phage ...
Anaelle Baud, Lucas Morinière, Imane El Idrissi, Fernando Clavijo‐Coppens, Elise Lacroix, Nicolas Taveau, Denis Costechareyre, Franck Bertolla   +7 more
wiley   +1 more source

Mutations in PMM2, a phosphomannomutase gene on chromosome 16p13, in carbohydrate-deficient glycoprotein type I syndrome (Jaeken syndrome)

, 1997
Carbohydrate-deficient glycoprotein syndrome type 1 (CDG1 or Jaeken syndrome) is the prototype of a class of genetic multisystem disorders characterized by defective glycosylation of glycoconjugates(1-4).
Veiga-da-Cunha, Maria, Gert Matthijs, Pardon, Els, Schollen, Els, Jaak Jaeken, Jaeken, Jaak, Els Schollen, Jean-Jacques Cassiman, Emile Van Schaftingen, Maria Veiga-Da-Cunha, Matthijs, Gert, Cassiman, Jean-Jacques, Van Schaftingen, Emile, Els Pardon   +13 more
core   +1 more source