Results 1 to 10 of about 54,708 (161)

Improved Synthesis of a Sub-Nanomolar Vinyl Phosphonate Inhibitor of Dehydroquinate Synthase [PDF]

open access: yesMolecules
In connection with a project aiming at the evaluation of antimicrobial agents, a vinyl phosphonate inhibitor of 3-dehydroquinate synthase was needed. As a result, the original five-step synthesis was reinvestigated resulting in a four-step process with ...
Ella Fitterer, Jean-Luc Montchamp
doaj   +2 more sources

Synthesis of Functionalized Diethyl(pyrrolidin-2-yl)phosphonate and Diethyl(5-oxopyrrolidin-2-yl)phosphonate

open access: yesMolecules, 2021
Short and efficient syntheses of functionalized (pyrrolidin-2-yl)phosphonate and (5-oxopyrrolidin-2-yl)phosphonate have been developed. The synthetic strategy involved the diastereospecific 1,3-dipolar cycloaddition of N-benzyl-C-(diethoxyphosphoryl ...
Iwona E. Głowacka   +3 more
doaj   +1 more source

Influence of Phosphorus Structures and Their Oxidation States on Flame-Retardant Properties of Polyhydroxyurethanes

open access: yesMolecules, 2023
This article focuses on the synthesis of polyhydroxyurethane (PHU) materials containing novel phosphorus flame retardants (FR). Four different phosphorus compounds were grafted onto cyclic carbonate: 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide ...
Maxinne Denis   +4 more
doaj   +1 more source

The facilitating role of phycospheric heterotrophic bacteria in cyanobacterial phosphonate availability and Microcystis bloom maintenance

open access: yesMicrobiome, 2023
Background Phosphonates are the main components in the global phosphorus redox cycle. Little is known about phosphonate metabolism in freshwater ecosystems, although rapid consumption of phosphonates has been observed frequently.
Liang Zhao   +14 more
doaj   +1 more source

Diethyl [(2,5-diiodo-4-methylphenyl)methyl]phosphonate

open access: yesIUCrData, 2021
The title compound, C12H17I2O3P, was prepared in three steps from p-xylene. Heterodimers between nearly identical molecules are connected via three hydrogen bonds from benzylic and ester methylene groups to phosphonate. The dimers form chains along the a-
Dieter Schollmeyer   +2 more
doaj   +1 more source

A Novel Biosynthetic Gene Cluster Across the Pantoea Species Complex Is Important for Pathogenicity in Onion

open access: yesMolecular Plant-Microbe Interactions, 2023
Onion center rot is caused by at least four species of genus Pantoea (P. ananatis, P. agglomerans, P. allii, and P. stewartii subsp. indologenes). Critical onion pathogenicity determinants for P.
Mei Zhao   +8 more
doaj   +1 more source

A Novel Durable Flame Retardant with Phosphonate Groups and Reactive Ammonium Phosphorus Acid Groups for Cotton Fabrics

open access: yesJournal of Natural Fibers, 2022
A novel flame retardant, tetraethylene pentamine heptamethylene tetraphosphonate dimethyl ester ammonium triphosphorus acid (TPHTDEAT), was synthesized and characterized by NMR.
Peiyi Zhao   +4 more
doaj   +1 more source

Diethyl(benzamido(diisopropoxyphosphoryl)methyl) phosphonate

open access: yesMolbank, 2022
Bisphosphonates are widely used in medicine and related areas, mainly for the treatment of bone diseases, such as osteoporosis. However, their synthesis is usually performed under harsh reaction conditions.
Adrián López-Francés   +3 more
doaj   +1 more source

Room-Temperature Alternative to the Arbuzov Reaction: The Reductive Deoxygenation of Acyl Phosphonates [PDF]

open access: yes, 2010
The reductive deoxygenation of acyl phosphonates using a Wolff−Kishner-like sequence is described. This transformation allows direct access to alkyl phosphonates from acyl phosphonates at room temperature. The method can be combined with acyl phosphonate
Dougherty, Dennis A.   +1 more
core   +2 more sources

Synthesis of 5-substituted 2'-deoxyuridine-5'-phosphonate analogues and evaluation of their antiviral activity [PDF]

open access: yes, 2012
A small series of 5-(hetero)aryl-modified nucleoside phosphonates was synthesized via an 8-step procedure including a Wittig reaction and Suzuki-Miyaura coupling.
Balzarini, Jan   +4 more
core   +1 more source

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