Results 1 to 10 of about 54,708 (161)
Improved Synthesis of a Sub-Nanomolar Vinyl Phosphonate Inhibitor of Dehydroquinate Synthase [PDF]
In connection with a project aiming at the evaluation of antimicrobial agents, a vinyl phosphonate inhibitor of 3-dehydroquinate synthase was needed. As a result, the original five-step synthesis was reinvestigated resulting in a four-step process with ...
Ella Fitterer, Jean-Luc Montchamp
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Short and efficient syntheses of functionalized (pyrrolidin-2-yl)phosphonate and (5-oxopyrrolidin-2-yl)phosphonate have been developed. The synthetic strategy involved the diastereospecific 1,3-dipolar cycloaddition of N-benzyl-C-(diethoxyphosphoryl ...
Iwona E. Głowacka +3 more
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This article focuses on the synthesis of polyhydroxyurethane (PHU) materials containing novel phosphorus flame retardants (FR). Four different phosphorus compounds were grafted onto cyclic carbonate: 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide ...
Maxinne Denis +4 more
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Background Phosphonates are the main components in the global phosphorus redox cycle. Little is known about phosphonate metabolism in freshwater ecosystems, although rapid consumption of phosphonates has been observed frequently.
Liang Zhao +14 more
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Diethyl [(2,5-diiodo-4-methylphenyl)methyl]phosphonate
The title compound, C12H17I2O3P, was prepared in three steps from p-xylene. Heterodimers between nearly identical molecules are connected via three hydrogen bonds from benzylic and ester methylene groups to phosphonate. The dimers form chains along the a-
Dieter Schollmeyer +2 more
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Onion center rot is caused by at least four species of genus Pantoea (P. ananatis, P. agglomerans, P. allii, and P. stewartii subsp. indologenes). Critical onion pathogenicity determinants for P.
Mei Zhao +8 more
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A novel flame retardant, tetraethylene pentamine heptamethylene tetraphosphonate dimethyl ester ammonium triphosphorus acid (TPHTDEAT), was synthesized and characterized by NMR.
Peiyi Zhao +4 more
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Diethyl(benzamido(diisopropoxyphosphoryl)methyl) phosphonate
Bisphosphonates are widely used in medicine and related areas, mainly for the treatment of bone diseases, such as osteoporosis. However, their synthesis is usually performed under harsh reaction conditions.
Adrián López-Francés +3 more
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Room-Temperature Alternative to the Arbuzov Reaction: The Reductive Deoxygenation of Acyl Phosphonates [PDF]
The reductive deoxygenation of acyl phosphonates using a Wolff−Kishner-like sequence is described. This transformation allows direct access to alkyl phosphonates from acyl phosphonates at room temperature. The method can be combined with acyl phosphonate
Dougherty, Dennis A. +1 more
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Synthesis of 5-substituted 2'-deoxyuridine-5'-phosphonate analogues and evaluation of their antiviral activity [PDF]
A small series of 5-(hetero)aryl-modified nucleoside phosphonates was synthesized via an 8-step procedure including a Wittig reaction and Suzuki-Miyaura coupling.
Balzarini, Jan +4 more
core +1 more source

