Results 11 to 20 of about 54,764 (213)

Phosphonate and Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthases: A Structure-Guided Perspective

open access: yesFrontiers in Chemistry, 2021
Phosphonates and bisphosphonates have proven their pharmacological utility as inhibitors of enzymes that metabolize phosphate and pyrophosphate substrates. The blockbuster class of drugs nitrogen-containing bisphosphonates represent one of the best-known
Jaeok Park   +3 more
doaj   +1 more source

Structural basis of the chiral selectivity of Pseudomonas cepacia lipase [PDF]

open access: yes, 1998
To investigate the enantioselectivity of Pseudomonas cepacia lipase, inhibition studies were performed with SC- and RC-(RP,SP)-1,2-dialkylcarbamoylglycero-3-O-p-nitrophenyl alkylphosphonates of different alkyl chain lengths. P.
Dijkstra, Bauke W.,   +4 more
core   +2 more sources

Nanocomposites and methods for synthesis and use thereof [PDF]

open access: yes, 2009
Nanocomposite compositions and methods of synthesis of the compositions are described. In particular, liquid crystal-functionalized nanoparticles, liquid crystal-templated nanoparticles, nanocomposite compositions including the nanoparticles, and ...
Furman, Benjamin R.   +3 more
core   +1 more source

A Pyrene- and Phosphonate-Containing Fluorescent Probe as Guest Molecule in a Host Polymer Matrix

open access: yesMolecules, 2013
New host-guest materials have been prepared by incorporation of a home-made organic probe displaying a pyrene motif and a phosphonate function into a regular amphiphilic copolymer. Using powder X-Ray diffraction, photoluminescence and FT-IR spectroscopy,
Jacqueline Marchand-Brynaert   +3 more
doaj   +1 more source

Variation of benzyl anions in MgAl-layered double hydroxides: Fire and thermal properties in PMMA [PDF]

open access: yes, 2009
Magnesium aluminum layered double hydroxides (MgAl-LDHs) intercalated with a range of benzyl anions were prepared using the coprecipitation method. The benzyl anions differ in functionality (i.e.
Chen, Dan   +3 more
core   +2 more sources

Organophosphorus Chemistry for the Synthesis of Dendrimers

open access: yesMolecules, 2012
Dendrimers are multifunctional, hyperbranched and perfectly defined macromolecules, synthesized layer after layer in an iterative manner. Besides the nature of the terminal groups responsible for most of the properties, the nature of the internal ...
Jean-Pierre Majoral   +3 more
doaj   +1 more source

Phosphorus Modified Cardanol: A Greener Route to Reduce VolaTile Organic Compounds and Impart Flame Retardant Properties to Alkyd Resin Coatings

open access: yesMolecules, 2022
Novel phosphorylated cardanol molecules based on phosphonate (PO3CR) and phosphate (PO4CR) functions were synthetized. Those molecules have two main actions which are described in this article: the reduction in volatile organic compounds (VOC) and the ...
Maxinne Denis   +5 more
doaj   +1 more source

Divergent strategy for the synthesis of α-aryl-substituted fosmidomycin analogues [PDF]

open access: yes, 2007
Fosmidomycin is the first representative of a new class of antimalarial drugs acting through inhibition of 1-deoxy-D-xylulose 5-phosphate ( DOXP) reductoisomerase (DXR), an essential enzyme in the non-mevalonate pathway for the synthesis of isoprenoids ...
Devreux, Vincent   +5 more
core   +2 more sources

The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis

open access: yesNature Communications, 2019
Phosphonate modifications can be present on microbial cell surfaces. Here the authors perform bioinformatics analyses and observe a widespread occurrence of nucleotidyltransferase-encoding genes in bacterial phosphonate biosynthesis and functionally ...
Kyle Rice   +14 more
doaj   +1 more source

Acclimation responses of Arabidopsis thaliana to sustained phosphite treatments [PDF]

open access: yes, 2013
Phosphite () induces a range of physiological and developmental responses in plants by disturbing the homeostasis of the macronutrient phosphate. Because of its close structural resemblance to phosphate, phosphite impairs the sensing, membrane transport,
Berkowitz, O.   +7 more
core   +2 more sources

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