Results 101 to 110 of about 91,004 (275)

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor, E. N. Chow, M. Thomas, L. Johnson, A. Siefert, B. Wagner, J. B. Engiles, H. L. Reesink   +7 more
wiley   +1 more source

PAPE (Prefractionation-Assisted Phosphoprotein Enrichment): A Novel Approach for Phosphoproteomic Analysis of Green Tissues from Plants

Proteomes, 2013
Phosphorylation is an important post-translational protein modification with regulatory roles in diverse cellular signaling pathways. Despite recent advances in mass spectrometry, the detection of phosphoproteins involved in signaling is still ...
Ines Lassowskat, Kai Naumann, Justin Lee, Dierk Scheel   +3 more
doaj   +1 more source

Ca2+ Uptake, Ca2+‐ATPase Activity, Phosphoprotein Formation and Phosphate Turnover in a Microsomal Fraction of Smooth Muscle

, 1981
Vesicles capable of phosphate-stimulated calcium uptake were isolated from the microsomal fraction of the smooth muscle of the pig stomach according to a previously described procedure which consists in increasing the density of the vesicles by loading ...
Hasselbach, W., Raeymaekers, L.
core   +1 more source

Spatial distribution of DARPP-32 in dendritic spines.

PLoS ONE, 2013
The phosphoprotein DARPP-32 (dopamine and cyclic adenosine 3´, 5´-monophosphate-regulated phosphoprotein, 32 kDa) is an important component in the molecular regulation of postsynaptic signaling in neostriatum.
Hans Blom, Daniel Rönnlund, Lena Scott, Linda Westin, Jerker Widengren, Anita Aperia, Hjalmar Brismar   +6 more
doaj   +1 more source

Pre-crisis mouse cells show strain-specific covariation in the amount of 54-kilodalton phosphoprotein and in susceptibility to transformation by simian virus 40. [PDF]

, 1983
We have used several inbred mouse strains to examine the role of the 54-kilodalton (kDa) cellular phosphoprotein in transformation by the papovavirus simian virus 40.
S. Chen, Chen, S, Blanck, G, Pollack, R E, G. Blanck, R. E. Pollack, Chen, S., Blanck, G., Pollack, Robert   +8 more
core   +1 more source

Deletion of FAST (Fas activated serine/threonine phosphoprotein) ameliorates immune complex arthritis in mice

, 2017
Fas-activated serine/threonine phosphoprotein (FAST) is a multifunctional protein localized in the nucleus, cytoplasm, and mitochondria.
Chen, Mei, Eirós, José M., Orduña, Antonio, Anderson, Paul, Fuente, Miguel A. de la, Simarro-Grande, María   +5 more
core   +1 more source

Majorbio Cloud 2026 Update: An End‐to‐End Solution for Proteomics Research

iMetaMed, EarlyView.
The recent upgrade of Majorbio Cloud facilitates a more streamlined and accurate research process, aiding researchers across the various proteomics subfields. Furthermore, it propels the advancement of multi‐layered, multi‐omics scientific investigations centered around proteins.
Caiping Shi, Chang Han, Jichen Han, Bing Yang, Yachen Dong, Jianhua Zhao, Binxu Liu, Rundong Fang, Wenyao Fu, Jiawen Ma, Meng Luo, Lixing Feng, Yitong Feng, Huimin Cui, Mengxi Li, Huasheng Huang, Xianglin Zhang, Kegang Yu   +17 more
wiley   +1 more source

Hepatocyte‐Centered Regulation of MASH Fibrosis: From Animal Models to Molecular Mechanisms and Targeted Therapies

iNew Medicine, EarlyView.
This review highlights hepatocytes as active regulators of MASH fibrosis through secreted proteins, metabolites, and extracellular vesicles that modulate hepatic stellate cell activation. These hepatocyte–stellate cell communication pathways provide a mechanistic framework for developing targeted antifibrotic therapies, including hepatocyte‐directed ...
Eui Jung Jung, Xiaobo Wang
wiley   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

DS_10.1177_0022034518784260 – Supplemental material for Hydrogen Peroxide Might Bleach Natural Dentin by Oxidizing Phosphoprotein

, 2018
Supplemental material, DS_10.1177_0022034518784260 for Hydrogen Peroxide Might Bleach Natural Dentin by Oxidizing Phosphoprotein by T. Jiang, Y.R. Guo, X.W. Feng, Y. Sa, X. Yang, M. Wang, P. Li and Y.N.
M. Wang (14838), P. Li (1413397), Y.N. Wang (5505089), Y.R. Guo (5505086), Y. Sa (5505095), X. Yang (2201716), T. Jiang (5505098), X.W. Feng (5505092)   +7 more
core   +1 more source