Results 111 to 120 of about 81,959 (297)

Immunoblot analysis of FLAG-BrBRI1 kinase phosphoprotein production over a time course.

open access: yes, 2015
Immunoblot analysis of FLAG-BrBRI1 kinase phosphoprotein production over a time course.
Vignesh Dhandapani (829058)   +6 more
core   +1 more source

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino   +3 more
wiley   +1 more source

Association between the expression of secreted phosphoprotein - related genes and prognosis of human cancer

open access: yesBMC Cancer, 2019
Background While many studies have assessed the predictive value of secreted phosphoprotein (SPP) genes in cancer, the findings have been inconsistent. To resolve these inconsistencies, we systematically analyzed the available data to determine whether ...
Yaqin Tu, Cai Chen, Guorun Fan
doaj   +1 more source

Innate immunity shapes the persistent transmission of plant viruses by insect vectors

open access: yesNew Plant Protection, EarlyView.
In this review, we focus on two key aspects of the virus–vector interplay: (1) persistently transmitted viruses utilize host factors to overcome transmission barriers; and (2) molecular recognition activates antiviral immunity and subsequent viral counter‐defense. Understanding these interactions offers critical insights for developing novel strategies
Gang Lu, Chuanxi Zhang, Junmin Li
wiley   +1 more source

Dimerization of Rabies Virus Phosphoprotein and Phosphorylation of Its Nucleoprotein Enhance Their Binding Affinity

open access: yesViruses
The dynamic interplay between a multimeric phosphoprotein (P) and polymeric nucleoprotein (N) in complex with the viral RNA is at the heart of the functioning of the RNA-synthesizing machine of negative-sense RNA viruses of the order Mononegavirales.
Euripedes de Almeida Ribeiro   +3 more
doaj   +1 more source

Phosphoprotein staining of two-dimensional electrophoresis gels (pH 5–8) indicates phosphorylated αA-crystallins

open access: yes, 2011
Numbers identify the equivalent αA-crystallin spots on gels stained with the total protein stain () and the phosphoprotein-specific stain (). Labels and arrows indicate α-crystallin spots that were not detected by the phosphoprotein stain.Copyright ...
Mason Posner (46038)   +5 more
core   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

Phosphoprotein phosphatase activity of sea urchin spermatozoa

open access: yes, 1982
Spermatozoa of the sea urchin Strongylocentrotus purpuratus were shown to contain phosphoprotein phosphatases capable of dephosphorylating phosphohistones and phosphorylase a.
Swarup, Ghanshyam, Garbers, David L.
core   +1 more source

The Replication Function of Rabies Virus P Protein Is Regulated by a Novel Phosphorylation Site in the N-Terminal N Protein-Binding Region

open access: yesViruses
The rabies virus (RABV) phosphoprotein (P protein) has multiple functions, including acting as the essential non-catalytic cofactor of the viral polymerase (L protein) for genome replication and transcription; the principal viral antagonist of the ...
Ericka Tudhope   +8 more
doaj   +1 more source

Modular Organization of Rabies Virus Phosphoprotein

open access: yes, 2009
International audienceA phosphoprotein (P) is found in all viruses of the Mononegavirales order These proteins form homo-oligomers, fulfil similar roles in the replication cycles of the various viruses, but differ in their length and oligomerization ...
Longhi, Sonia   +7 more
core   +1 more source

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