Results 171 to 180 of about 87,699 (269)

Endogenous Bornavirus‐Like Nucleoprotein 1 Regulates Cellular Processes and DNA Double‐Strand Breaks in U‐87 MG Glioblastoma Cells

open access: yesCancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Glioblastoma (GBM) is a common brain cancer with a poor prognosis and a high recurrence rate. DNA damage repair plays a crucial role in GBM carcinogenesis and treatment resistance. Human endogenous bornavirus‐like nucleoprotein 1 (EBLN1) regulates cellular processes and genetic stability. However, the biological role of EBLN1 in GBM
Jing Liang   +6 more
wiley   +1 more source

Dysregulated circRNA expression profile and associated miRNA sponging in abnormal lung development in congenital diaphragmatic hernia

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Circular RNAs (circRNAs) are stable, stage‐ and tissue‐specific regulators of gene expression warranting their study in abnormal fetal lung development in congenital diaphragmatic hernia (CDH). We present a CDH‐specific circRNA biosignature in the nitrofen rat model (E15/E21) using orthogonal validation with human comparison and discovered conserved ...
Marietta Jank   +16 more
wiley   +1 more source

Tryptophan metabolism in colorectal cancer: From mechanistic insights to novel therapeutic strategies

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Tryptophan metabolism modulates CRC via three microbiota‐regulated pathways with distinct dual‐mode effects. The kynurenine pathway provides biomarkers, serotonin pathway supports SSRI‐combined immunotherapy, indole pathway yields immunostimulatory metabolites, collectively offering translational prospects.
Ran Wang   +5 more
wiley   +1 more source

Oxidized phosphatidylcholines inhibit airway smooth muscle β2-adrenergic receptors via protein kinase C. [PDF]

open access: yesAm J Respir Cell Mol Biol
Vaghasiya J   +12 more
europepmc   +1 more source

Spatiotemporal immune heterogeneity and precision immunotherapy for ovarian cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Graphical Highlights Spatiotemporal immune heterogeneity shapes distinct and evolving immune ecosystems in ovarian cancer. Multimodal biomarkers enable biologically informed patient stratification beyond static single‐marker approaches. Precision immunotherapy should match dominant immune barriers across lesions and treatment stages.
Xinfeng Yang   +9 more
wiley   +1 more source

Proteogenomic decoding of chemotherapy resistance in patients with triple-negative breast cancer. [PDF]

open access: yesGenome Biol
Lee DK   +20 more
europepmc   +1 more source

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