Results 171 to 180 of about 91,004 (275)

Integrating ANP32A expression with Ann Arbor stage refines prognostic stratification in extranodal NK/T-cell lymphoma. [PDF]

Diagn Pathol
Huo Y, Zhang Z, Liu E, Wang G, Zhao W, Zhang D, Zhang Y, Shang Y, Du H, Yu J, Zhang C, Lu S, Li W.   +12 more
europepmc   +1 more source

Dissecting the Radioresponse Heterogeneity of Lung Adenocarcinoma Cells From the Perspective of Transcriptional and Regulatory Landscape

MedComm, Volume 7, Issue 11, November 2026.
Radiation‐associated transcriptional and regulatory cell states drive heterogeneous radioresponses in isogenic lung adenocarcinoma cells. ABSTRACT Radioresistance severely compromises radiotherapy efficacy for lung adenocarcinoma (LUAD), yet the intrinsic heterogeneity of cellular radioresponses among isogenic tumor cells remains poorly characterized ...
Huan Tao, Yaru Li, Leixin Ge, Lu Chen, Yang Zheng, Feiyue Ma, Changhui Ge, Hanjiang Fu, Yu Sun, Longteng Wang, Junting Wang, Xuemei Bai, Hao Li, Xiaochen Bo, Hebing Chen, Xiaofei Zheng   +15 more
wiley   +1 more source

Identification and validation of SPP1 as a prognostic biomarker in interstitial lung disease subtypes by single-cell sequencing. [PDF]

Respir Res
Ji T, Li Y, Zhang S, Zhang C, Xie W, Wang S, Liu Q, Xu H, Dai J.   +8 more
europepmc   +1 more source

Histone Deacetylase 3‐Progesterone Receptor Cooperation Regulates Progesterone Responsiveness in the Uterus

MedComm, Volume 7, Issue 11, November 2026.
HDAC3 and PGR exhibit coordinated expression and chromatin occupancy in the receptive endometrium. Loss of HDAC3‐PGR cooperation in endometriosis disrupts progesterone‐responsive gene regulation and impairs uterine receptivity. ABSTRACT Endometriosis affects a substantial proportion of women of reproductive age, with 30%–50% affected by infertility.
Sohyeon Yun, Rong Li, Soo Lim Kim, Loan Thi Kim Nguyen, Shamsun Nahar, Keun Cheon Kim, DaHye Kang, Eunhee M. Jeong, Lisa Brennaman, Mistie P. Mills, Steven L. Young, Bruce A. Lessey, Tae Hoon Kim, Jung‐Yoon Yoo, Jae‐Wook Jeong   +14 more
wiley   +1 more source

A comprehensive proteome and the first phosphoproteome reveal extensive phosphorylation of carbohydrate metabolism in Cryptosporidium parvum sporozoites. [PDF]

Parasit Vectors
Wang D, Li M, Wang C, Li H, Yin J, Zhu G.   +5 more
europepmc   +1 more source

Mitochondria in Viral Infections: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 11, November 2026.
Viral infections remodel mitochondrial function through direct viral regulation and infection‐induced changes in host cellular processes. These alterations affect OXPHOS, mitochondrial metabolism, calcium homeostasis, membrane potential, redox regulation, dynamics, and apoptosis, with distinct effects on viral replication and host antiviral responses ...
Ha Young Oh, Hye Jin Shin
wiley   +1 more source

Statement of Retraction: Metformin suppresses lung adenocarcinoma by downregulating long non-coding RNA (lncRNA) AFAP1-AS1 and secreted phosphoprotein 1 (SPP1) while upregulating miR-3163. [PDF]

Bioengineered
europepmc   +1 more source

Ephrin B2 and Ephrin B3 are receptors for a novel putative henipavirus with zoonotic potential. [PDF]

PLoS Negl Trop Dis
Dai G, Yao S, Chen W, Zhang J, Du X, Zhao Y, Jin Z, Zhang G.   +7 more
europepmc   +1 more source

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

Medicinal Research Reviews, Volume 46, Issue 6, Page 1735-1752, November 2026.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino, Manuela Bartolini, Rudolf Andrys, Kamil Musilek   +3 more
wiley   +1 more source

Advances in Cytosolic dsRNA Sensing of Viral Infections

Immunology &Cell Biology, Volume 104, Issue 10, Page 975-986, November‐December 2026.
Activation of cytosolic dsRNA sensors by viral infection generates multiple outcomes. dsRNA generated during viral infection, either of viral origin or from endogenous sources, can activate multiple cytosolic dsRNA sensors. Activation of PKR critically induces protein translation shutdown via phosphorylation of eukaryotic translation initiation factor ...
Sofia Maceratessi, Natalia G. Sampaio
wiley   +1 more source