Results 181 to 190 of about 81,959 (297)

Exosomal miR‐4644 Targets SPRY3 to Promote Proliferation and Invasion of Pancreatic Cancer

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Tumor‐derived exosomes (TDEs) can carry diverse genetic material that modulates pancreatic cancer (PC) proliferation and invasion. Despite this, the involvement of microRNAs (miRNAs) in TDE‐mediated tumor progression in PC remains inadequately explored. Methods Ultracentrifugation was used to isolate exosomes derived from AsPC‐1 and
Xiangyu Chu, Dongqi Li, Fusheng Zhang, Yongsu Ma, Yongqi Deng, Chen Wang, Xiaodong Tian, Yanlian Yang, Yinmo Yang   +8 more
wiley   +1 more source

Phylogenetic and motif-based genomic analysis of Mokola virus: implications for regional divergence and data gaps. [PDF]

BMC Genom Data
Oladipo EK, Ogunniran JA, Akinpelu OS, Ajadi KA, Andy BO, Awobiyi HO, Iwalokun BA, Kolawole OM, Onyeaka H, Oloke JK.   +9 more
europepmc   +1 more source

Exosome‐mediated miR‐4660 delivery inhibits OPN promoted hepatoma cells aggression through targeting LGALS3BP

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
miR‐4660 was found to be downregulated in exosomes derived from SMMC‐OPN cells, a stable HCC cell line that overexpresses OPN. LGALS3BP has been identified as a direct target of miR‐4660, with its expression levels elevated in both SMMC‐OPN cells and their secreted exosomes.
Cuihua Liu, Riwen An, Ting Lin, Lei Qu, Xiaopeng Zheng, Jingkun Lu, Mei Hong, Pengwei Zhao, Fangxin Zhao, Xuan Zhang   +9 more
wiley   +1 more source

Molecular prevalence, genomic characterization, and zoonotic potential of novel paramyxovirus and hepacivirus in Alexandromys fortis, Republic of Korea. [PDF]

Vet Res
Pangestu HS, Yang I, Natasha A, Rajoriya S, Hennisa H, Park J, Park K, Kim J, Kim SG, Klein TA, Kim HC, Oh Y, Song JW, Kim WK.   +13 more
europepmc   +1 more source

Proline‐Rich Transmembrane Protein 2 Is Variably Expressed Across Excitatory and Inhibitory Neurons in Mouse Motor Circuits

Journal of Comparative Neurology, Volume 534, Issue 6, June 2026.
Prrt2, a causal gene for paroxysmal kinesigenic dyskinesia, was sparsely expressed in nigrostriatal dopaminergic neurons, but alternatively in excitatory (within the cerebral cortex and cerebellum) or inhibitory (within the basal ganglia) neurons in a region‐dependent manner, suggesting that Prrt2 functions in both the basal ganglia and cerebellar ...
Daisuke Hatta, Kaori Watanabe, Akira Kinoshita, Koh‐Ichiro Yoshiura, Naohiro Kurotaki, Keiro Shirotani, Nobuhisa Iwata   +6 more
wiley   +1 more source

Harnessing Cytomegalovirus DNAemia and CMV-Specific Cell-Mediated Immunity in Pediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients. [PDF]

J Korean Med Sci
Lee S, Kim G, Kim JH, Choi ES, Kang SH, Kim H, Koh KN, Im HJ, Lee J.   +8 more
europepmc   +1 more source

Unveiling Candidate Markers for Drug Resistance or Synthetic Lethality in Cervical Cancer: Integrative Analysis of Genetic and Pharmacoprofiling

Cancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Introduction Systemic cervical cancer management continues to be challenging. Numerous chemotherapies have been approved, but predicting response is difficult due to the lack of biomarkers. Here, we analyze the genetic and protein profiles of 20 cervical cancer cell lines (CCCLs) and explore their correlation with drug response patterns to ...
Suzy Scholl, Elaine Del Nery, Pierre Gestraud, Maral Halladjian, Elodie Girard, Adèle Soria, Elodie Anthony, Leanne De Koning, Nicolas Servant, Els Berns, Maud Kamal   +10 more
wiley   +1 more source

Clinical significance of differential plasma proteins levels in the diagnosis of epithelial ovarian cancer. [PDF]

World J Exp Med
Ibrahim NH, Abdellateif MS, Serag DS, Laymouna A, Elaguizy MS, Halim RMA.   +5 more
europepmc   +1 more source

Clinical significance of urinary SPP1 as a potential new diagnostic marker for oesophageal squamous cell carcinoma

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
In this study, we investigate the potential of urinary secreted phosphoprotein 1 (SPP1) levels as a noninvasive diagnostic biomarker for oesophageal squamous cell carcinoma (ESCC). Our study suggests that urinary SPP1 may serve as a novel biomarker for the detection of ESCC. Abstract Background Urinary proteins could be useful as noninvasive biomarkers
Bingrong Guo, Jiawei Zhang, Jianpeng Che, Yuan Zhong, Linlin Ji, Wei Li   +5 more
wiley   +1 more source

Causal relationships between antibody-induced immune responses and sepsis: Evidence from genetic studies. [PDF]

Medicine (Baltimore)
Li L, Liu L, Yan J, Tan J, Xie S.
europepmc   +1 more source