Results 201 to 210 of about 87,699 (269)

Supraphysiological 25‐Hydroxyvitamin D3 and Calcipotriol Induce Reactive Oxygen Species, Mitochondrial Dysfunction and Apoptosis in HeLa Cervical Cancer Cells

FASEB BioAdvances, Volume 8, Issue 9, September 2026.
Supraphysiological 25(OH)D3 and calcipotriol induced ROS accumulation or redox disturbance, increased mitochondrial membrane depolarization, reduced antioxidant enzyme activity, and caused apoptotic cell death in HeLa cells. ABSTRACT Cervical cancer remains a major global health challenge, necessitating continued advances in therapeutic strategies ...
Hoi Ching Cherry Chan, Sachin Bhoora, Esther Zhou, Sumari Marais, Tahir S. Pillay, Rivak Punchoo   +5 more
wiley   +1 more source

Nucleolar targeting of lyssavirus P-protein is isoform- and phylogroup-specific. [PDF]

J Gen Virol
Moseley GW, Zhang Y, David CT, Rawlinson SM.   +3 more
europepmc   +1 more source

Phosphoprotein Profile [PDF]

, 2020
openaire   +1 more source

Twisting the End Game: How Telomere Chromatin Modifications Shape Telomere Maintenance

Aging Cell, Volume 25, Issue 9, September 2026.
Chromatin modifications on telomeres are linked to the mode of telomere DNA replication. A coupled feedforward loop model is proposed based on these to lock the ALT cancer cells in this alternative mode of telomere replication. ABSTRACT Cell division inevitably shortens telomeric DNA owing to the end‐replication problem.
Jie Wang, Yuehui Su, Chao Chen, Yueying Li, Jiajia Han, Liping Du, Liyun Zheng, Ya‐Long Dang, Ying Peng   +8 more
wiley   +1 more source

Lipopolysaccharide-binding proteins and vasodilator-stimulated phosphoproteins as novel screening biomarkers for advanced adenoma and colorectal cancer. [PDF]

Discov Oncol
Tan C, Wang QQ, Zhou YC, Qin G, Yao SK.
europepmc   +1 more source

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

British Journal of Pharmacology, Volume 183, Issue 17, Page 5315-5335, September 2026.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah, Joshua Richard, Suvankar Ghosh, Jillian Jerwick, Joice T. Gavali, Raymond B. Penn, Alexander D. MacKerell Jr, Deepak A. Deshpande   +7 more
wiley   +1 more source

Conserved Phosphoprotein Networks Identify Actionable Adhesion/Wnt and Metallothionein Modules in Cholangiocarcinoma. [PDF]

Med Sci (Basel)
Sitthirak S, Roytrakul S, Wangwiwatsin A, Namwat N, Klanrit P, Dokduang H, Sa-Ngiamwibool P, Titapun A, Jareanrat A, Thanasukarn V, Khuntikeo N, Tean TB, Boulter L, Murakami Y, Loilome W.   +14 more
europepmc   +1 more source

Modeling the Histogenetic Switch Between Enameloid and Enamel

Evolution &Development, Volume 28, Issue 3, September 2026.
This evo–devo exploration of ~550,000 histogenetic simulations forming dentine, enameloid, and enamel identifies 38 independent ways to induce the enameloid–enamel transition, with delayed matrix vesicle secretion (SVO‐) emerging as the key modification, providing new insights into the origin of enamel in early osteichthyans.
Guillaume Houée, Jérémie Bardin, Damien Germain, Nicolas Goudemand   +3 more
wiley   +1 more source

The¹H, ¹⁵N and¹³C backbone resonance assignments of an intrinsically disordered region (124-270) of BRCA1 associated RING domain 1 (BARD1). [PDF]

Biomol NMR Assign
Dinh HH, Jasper AM, Baudin A, Sung P, Libich DS.   +4 more
europepmc   +1 more source

Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk

International Endodontic Journal, Volume 59, Issue 9, Page 1743-1759, September 2026.
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar, M. Huang, M. M. Abdalla, P. Neelakantan, C. K. Y. Yiu   +4 more
wiley   +1 more source