Results 91 to 100 of about 18,289 (229)
A Mass Spectrometry-Based Approach to Identify Phosphoprotein Phosphatases and their Interactors. [PDF]
J Vis Exp, 2022 Smolen KA, Kettenbach AN.
europepmc +1 more source
14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses
The Journal of Physiology, EarlyView.Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley +1 more source
Affinity-based profiling of endogenous phosphoprotein phosphatases by mass spectrometry. [PDF]
Nat Protoc, 2021 Brauer BL +5 more
europepmc +1 more source
Phosphatase Regulation of CFTR [PDF]
, 2003 The cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is tightly regulated by the opposing actions of protein kinases and phosphatases. Its phosphorylation and activation by protein kinases A (PKA) and C (PKC) have been studied
Hanrahan, John W. +2 more
core
The Journal of Physiology, EarlyView.Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley +1 more source
The role of phosphoprotein phosphatases catalytic subunit genes in pancreatic cancer. [PDF]
Biosci Rep, 2021 Hang J +6 more
europepmc +1 more source
Protein and Peptide Inhibitors of Mineralization: A Systematic Review of In Vitro Studies
Journal of Peptide Science, Volume 32, Issue 7, July 2026.In vitro evidence from crystallization assays demonstrates that peptides inhibit mineral nucleation and crystal growth through sequence‐dependent interactions (acidic residues and phosphorylation) with mineral surfaces. In cell cultures, these molecules reduce calcium deposition and ALP activity and modulate the expression of biomineralization‐related ...
Alberto Mimila‐Cortes +7 more
wiley +1 more source
Loss of SHP-1 in CD11c+ cells impairs anti-tumor immunity
Frontiers in ImmunologyBackgroundTyrosine kinases and phosphatases regulate protein phosphorylation and maintain cellular homeostasis. The phosphoprotein tyrosine phosphatase SHP-1 (encoded by the Ptpn6 gene) has been proposed as an immune checkpoint in CD8+ T cells in ...
Miguel Galán +16 more
doaj +1 more source
Targeting ATM pathway for therapeutic intervention in cancer [PDF]
, 2012 The Ataxia Telangiectasia Mutated gene encodes the ATM protein, a key element in the DNA damage response (DDR) signalling pathway responsible for maintaining genomic integrity within the cell.
Chakarov, Stoyan +4 more
core +3 more sources
Advanced Materials Interfaces, Volume 13, Issue 11, 9 June 2026.Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido +6 more
wiley +1 more source