Results 91 to 100 of about 40,005 (218)
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Integrated quantitative proteomic, phosphoproteomic, and transcriptomic analyses of human trophoblast stem cells identify stage‐specific kinase signaling networks that regulate trophoblast self‐renewal and differentiation into syncytiotrophoblasts and extravillous trophoblasts.
Rajnish Kumar +3 more
wiley +1 more source
Selective dephosphorylationo of proteins containing phosphotyrosine by alkaline phosphatases
, 1981 Histones specifically phosphorylated at either tyrosine (phospho-Tyr-histones) or serine and threonine (phospho-Ser-histones) were prepared and tested as substrates for so-called alkaline and protein phosphatases. Three different preparations of alkaline
Swarup, Ghanshyam +2 more
core +1 more source
Phosphoprotein phosphatase activity of sea urchin spermatozoa
, 1982 Spermatozoa of the sea urchin Strongylocentrotus purpuratus were shown to contain phosphoprotein phosphatases capable of dephosphorylating phosphohistones and phosphorylase a.
Swarup, Ghanshyam, Garbers, David L.
core +2 more sources
Role of serine-threonine phosphoprotein phosphatases in smooth muscle contractility
The degree of phosphorylation of Myosin Light Chain 20 (MLC20) is a major determinant of force generation in smooth muscle. Myosin phosphatases (MP) all contain Protein Phosphatase 1 as catalytic subunits and are the major enzymes that dephosphorylate ...
Paul J +4 more
core +4 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Loss of SHP-1 in CD11c+ cells impairs anti-tumor immunity
Frontiers in ImmunologyBackgroundTyrosine kinases and phosphatases regulate protein phosphorylation and maintain cellular homeostasis. The phosphoprotein tyrosine phosphatase SHP-1 (encoded by the Ptpn6 gene) has been proposed as an immune checkpoint in CD8+ T cells in ...
Miguel Galán +16 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, Volume 600, Issue 17, Page 2420-2436, September 2026.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Advanced Science, Volume 13, Issue 52, 18 September 2026.The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud +12 more
wiley +1 more source
The structure and mode of action of the dinoflagellate toxins
Iranian South Medical Journal, 2016 Background: Dinoflagellates are the major causative agents of harmful algal blooms. In different studies, it has been shown that many dinoflagellate species produce various natural toxins.
Akram Najafi, Iraj Nabipour
doaj
Advanced Science, Volume 13, Issue 53, 24 September 2026.Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu +9 more
wiley +1 more source