Results 81 to 90 of about 40,005 (218)
Rab11-FIP3 is a cell cycle-regulated phosphoprotein [PDF]
<b>BACKGROUND:</b> Rab11 and its effector molecule, Rab11-FIP3 (FIP3), associate with recycling endosomes and traffic into the furrow and midbody of cells during cytokinesis.
Xinzi Yu +49 more
core +1 more source
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley +1 more source
A Mass Spectrometry-Based Approach to Identify Phosphoprotein Phosphatases and their Interactors. [PDF]
Smolen KA, Kettenbach AN.
europepmc +1 more source
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires +15 more
wiley +1 more source
QUANTITATIVE PROTEOMIC STRATEGIES TO DETERMINE SUBSTRATE SPECIFICITIES OF PHOSPHOPROTEIN PHOSPHATASES [PDF]
Reversible phosphorylation is a crucial regulatory mechanism of cellular signaling pathways. Being the most prevalent post-translational modification (PTM) in the cells, with over 75% of all proteins detected to be phosphorylated, phosphorylation ...
Nguyen, Hieu Trung
core
Affinity-based profiling of endogenous phosphoprotein phosphatases by mass spectrometry. [PDF]
Brauer BL +5 more
europepmc +1 more source
Background and Purpose In contrast to neurons in the central nervous system, neurons in the peripheral nervous system can regenerate axons after injury via activation of a pro‐regenerative transcriptional programme. Pathogenic mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, and several small ...
Eun‐Hae Jang +11 more
wiley +1 more source
Dephosphorylation of perilipin by protein phosphatases present in rat adipocytes [PDF]
By incubating 32P-labelled adipocytes, and extracts from these cells, in the presence or absence of specific inhibitors, we evaluated the contribution of protein phosphatases PP1, PP2A and PP2C, to the dephosphorylation of perilipin, an acutely hormone ...
Londos, Constantine +9 more
core +1 more source
The role of phosphoprotein phosphatases catalytic subunit genes in pancreatic cancer. [PDF]
Hang J +6 more
europepmc +1 more source
Cardioprotective hormone relaxin‐2 showed relevant effects on rat skeletal muscle by altering proteins linked to muscle function, regeneration, differentiation, mitochondrial function, glucose metabolism, and structural integrity and organization. Specifically, relaxin‐2 reduced the expression of 95 proteins, increased 32, and elicited unique proteins ...
Xocas Vázquez‐Abuín +11 more
wiley +1 more source

