Results 111 to 120 of about 19,090 (263)

Hypoxia and the cytoskeleton

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

The Properties of Particulate Phosphoprotein Phosphatase

open access: yesJournal of Biological Chemistry, 1958
The very high metabolic activity of protein-bound phosphorus was first discovered by Davidson et al. (1) in P32 uptake experiments and subsequently confirmed in other laboratories. A possible explanation of these findings is that the primary step in oxidative phosphorylation results in the formation of a phosphorylated protein with subsequent transfer ...
openaire   +2 more sources

Sex Hormones Attenuate Pro‐Inflammatory Gene Expression in Nucleus Pulposus and Annulus Fibrosus Cells in a Cell‐Type Specific Manner

open access: yesJOR SPINE, Volume 9, Issue 1, March 2026.
Methodological overview of primary bovine NP and AF cell culture. Pro‐ and anti‐inflammatory gene and protein expression analyses were performed after 24 h of pro‐inflammatory stimulus, followed by 3 days of cotreating cells with sex hormones in addition to pro‐inflammatory cytokines.
Jeffrey L. Hutchinson   +2 more
wiley   +1 more source

Association Between Abnormal DNA Methylation and Altered Transcriptome in Muscle Five Years After Critical Illness

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Critically ill patients requiring intensive care unit (ICU) admission suffer from muscle weakness that persists for years. Recently, altered RNA expression was documented in muscle of former ICU patients 5 years after critical illness that suggested disrupted mitochondrial function, disturbed lipid metabolism and fibrosis, of which ...
Ceren Uzun Ayar   +4 more
wiley   +1 more source

Phycobilisome linker proteins are phosphorylated in Synechocystis sp. PCC 6803 [PDF]

open access: yes, 2005
The controversial issue of protein phosphorylation from the photosynthetic apparatus of Synechocystis sp. PCC 6803 has been reinvestigated using new detection tools that include various immunological and in vivo labeling approaches.
Ajlani, Ghada   +2 more
core   +1 more source

Differences in Src phosphorylation of PSD‐93 and PSD‐95 drive differences in scaffolding activity

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Scaffold proteins contain multiple binding modules that allow for co‐localization of proteins that lack a direct interaction. Evolution resulted in different combinations of binding modules that rewired existing signal transduction pathways.
Frank A. Mindlin   +3 more
wiley   +1 more source

Deficiency of Microglial‐Derived Spp1 Exacerbates Age‐Related Memory Decline by Impairing Mitochondrial Complex I Function

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Microglia‐derived Spp1 regulates OXPHOS via the AKT/Complex I pathway to mitigate age‐related memory decline. (Graphical Abstract was created using BioRender). ABSTRACT Age‐related memory decline is a hallmark of brain aging and a primary risk factor for neurodegenerative disorders.
Meiling Wang   +9 more
wiley   +1 more source

Proteomic profiling of porcine seminal extracellular vesicles reveals potential in vivo fertility biomarkers

open access: yesAndrology, Volume 14, Issue 2, Page 555-570, February 2026.
Abstract Background Predicting male fertility in farm animals remains a challenge. Seminal plasma (SP) contains a high amount of heterogeneous seminal extracellular vesicles (sEVs), believed involved in reproductive processes and maybe key to understanding male fertility.
Isabel Barranco   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy