Results 271 to 280 of about 73,329 (379)

Top‐Down Proteomics Study of Aging and Sexual Dimorphism of Zebrafish Brains

Journal of Mass Spectrometry, Volume 61, Issue 1, January 2026.
ABSTRACT Aging significantly impacts brain function and increases susceptibility to neurodegenerative diseases, with notable sex dimorphism observed in aging‐related dementia, such as Alzheimer's disease. To better understand the molecular mechanisms of aging and dementia, it is essential to globally and accurately characterize biomolecules (e.g ...
Mehrdad Falamarzi Askarani, William Poulos, Maryam Rahimzadeh Dashtaki, Seyed Amirhossein Sadeghi, Jose B. Cibelli, Fei Fang, Liangliang Sun   +6 more
wiley   +1 more source

Sex-specific phosphoproteome responses to calorie restriction and insulin in skeletal muscle from older rats. [PDF]

J Gerontol A Biol Sci Med Sci
Wang H, Madsen S, Needham EJ, Humphrey SJ, Zheng A, Arias EB, Stöckli J, Cutler HB, James DE, Cartee GD.   +9 more
europepmc   +1 more source

High-Throughput Phosphorylation Screening and Validation through Ti(IV)-Nanopolymer Functionalized Reverse Phase Phosphoprotein Array

, 2018
Ying Zhang, Chunzhao Zhao, Li Li, Chuan‐Chih Hsu, Jian‐Kang Zhu, Anton Iliuk, W. Andy Tao   +6 more
openalex   +2 more sources

Organoids in Cancer Research and Regenerative Medicine: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 1, January 2026.
The management of cancer and tissue regeneration remains a substantial challenge to global health. Organoids, which are stem cell‐derived three‐dimensional multicellular structures, are revolutionizing biomedical research. Therefore, this review highlights their applications in cancer research and regenerative medicine, while discussing current ...
Ruiyang Li, Yuezhou Wu, Zhu'anzhen Zheng, Fengjin Zhou, Ke Xu, Jiacan Su   +5 more
wiley   +1 more source

Type One Protein Phosphatase 4aD Negatively Regulates Cotton (<i>Gossypium hirsutum</i>) Salt Tolerance by Inhibiting the Phosphorylation of Kinases That Respond to Abscisic Acid. [PDF]

Int J Mol Sci
Cao P, Zhao M, Liu J, Du M, Tian X, Li F, Li Z.   +6 more
europepmc   +1 more source

Fibroblast‐specific palladin drives kidney fibrosis via MRTF–SRF signaling

The Journal of Pathology, Volume 268, Issue 1, Page 40-53, January 2026.
Abstract Fibrosis is a common end‐stage pathway of progressive chronic kidney diseases. Previously we demonstrated that myocardin‐related transcription factor (MRTF)–serum response factor (SRF) signaling drives the expression of fibrosis‐related molecules through actin cytoskeleton dynamics in renal fibroblasts.
Naoki Yamamoto, Norihiko Sakai, Yuta Yamamura, Daichi Kaikoi, Daiki Hayashi, Takahiro Matsuno, Akihiko Koshino, Keisuke Sako, Keisuke Horikoshi, Takahiro Yuasa, Akira Tamai, Taichiro Minami, Megumi Oshima, Shiori Nakagawa, Shinji Kitajima, Akinori Hara, Miho Shimizu, Jumpei Terakawa, Shin‐ichi Horike, Takiko Daikoku, Atsushi Mizokami, Hiroko Ikeda, Moeno Kadoguchi, Hiroshi Arakawa, Sumio Ohtsuki, David Lagares, Takashi Wada, Yasunori Iwata   +27 more
wiley   +1 more source

Tonic signaling of the B-cell antigen-specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages. [PDF]

Mol Oncol
Díez P, Juanes-Velasco P, García-Vaquero ML, Droste C, Landeira-Viñuela A, Alcoceba M, Fidalgo-Gómez H, Misiego-Herrero S, Navarro-Bailón A, Baile M, Bastida JM, Sanchez-Santos JM, Góngora R, Almeida J, Gonzalez-Diaz M, Orfao A, De Las Rivas J, Fuentes M.   +17 more
europepmc   +1 more source

A chemical-genetic approach to elucidate protein kinase function in planta [PDF]

, 2007
Böhmer, M., Romeis, T.
core   +1 more source

Dopamine- and cAMP-regulated phosphoprotein DARPP-32: phosphorylation of Ser-137 by casein kinase I inhibits dephosphorylation of Thr-34 by calcineurin.

, 1995
Frédéric Desdouits, Julio C. Siciliano, Paul Greengard, Jean‐Antoine Girault   +3 more
openalex   +2 more sources

PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation

Nature Cell Biology, 2009
J. Wu, J. Y. Guo, Wanli Tang, Chih-Sheng Yang, C. Freel, Cheng Chen, A. Nairn, S. Kornbluth   +7 more
semanticscholar   +1 more source