Results 301 to 310 of about 73,329 (379)

TRIM52 Protects Against Doxorubicin‐Induced Cardiac Inflammation, Oxidative Stress and Cardiac Injury

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Tripartite motif 52 (TRIM52) has been identified as a key regulator of inflammatory responses. However, its involvement in doxorubicin (DOX)‐induced cardiotoxicity (DIC) and the underlying molecular mechanisms remain poorly understood. To investigate the functional role of TRIM52, we employed an adeno‐associated virus serotype 9 (AAV9 ...
Zhaoxia Zhang   +8 more
wiley   +1 more source

Unveiling the Proteomic Landscape of Extracellular Vesicles: Implications for Neurodegeneration and Neuroprotection

open access: yesJournal of Neurochemistry, Volume 170, Issue 1, January 2026.
Extracellular vesicles (EVs) are tiny, membrane‐covered packets that cells naturally release to send molecular information to one another. In the brain, they function as couriers that move proteins, lipids, and other signals between neurons, glial cells, and the blood–brain barrier.
Berenice N. Bernal‐Vicente   +4 more
wiley   +1 more source

Adipose‐Derived Extracellular Vesicles and Intercellular Crosstalk With Skeletal Muscle: Implications for Sarcopenic Obesity and Metabolic Dysregulation

open access: yesObesity Reviews, Volume 27, Issue 1, Page 1-22, January 2026.
ABSTRACT Sarcopenic obesity, characterized by the concurrent presence of excess adiposity and diminished skeletal muscle mass and function, is closely linked to frailty, chronic inflammation, and insulin resistance. The increasing prevalence of sarcopenic obesity is driven by the global aging population, widespread adoption of sedentary lifestyles, and
Michael Macleod   +5 more
wiley   +1 more source

The Role of Innate Lymphoid Cells in the Pathogenesis of Hepatic Echinococcosis: A Literature Review

open access: yesParasite Immunology, Volume 48, Issue 1, January 2026.
ABSTRACT Hepatic echinococcosis (HE), a major zoonotic disease, remains endemic in pastoral regions of Western China, where its incidence is closely linked to geographical, livestock and sanitary conditions. The disease presents a significant clinical challenge due to the complexity of host–parasite interactions and a high recurrence rate. To date, the
Wei Ma   +3 more
wiley   +1 more source

Dietary nitrate supplementation mitigates age‐related changes at the neuromuscular junction in mice

open access: yesThe Journal of Physiology, Volume 604, Issue 2, Page 886-916, 15 January 2026.
Abstract figure legend Ageing is associated with a decline in muscle mass and strength, namely sarcopenia, significantly impacting the quality of life in older individuals. Different strategies are being explored to counteract these detrimental effects. In the present study, we investigated a non‐invasive nutritional approach: the impact of 2 months of
Maira Rossi   +9 more
wiley   +1 more source

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