Results 11 to 20 of about 24,002 (153)

Microvascular and systemic responses to novel PEGylated carboxyhaemoglobin-based oxygen carrier in a rat model of vaso-occlusive crisis

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Hypoxia drives sickle cell disease (SCD) by inducing sickle cell haemoglobin to polymerize and deform red blood cells (RBC) into the sickle shape.
William H. Nugent, Ronald Jubin, Peter J. Buontempo, Friedericke Kazo, Bjorn K. Song   +4 more
doaj   +1 more source

Data from Multiphoton Phosphorescence Quenching Microscopy Reveals Kinetics of Tumor Oxygenation during Antiangiogenesis and Angiotensin Signaling Inhibition

, 2023
<div>AbstractPurpose:<p>The abnormal function of tumor blood vessels causes tissue hypoxia, promoting disease progression and treatment resistance. Although tumor microenvironment normalization strategies can alleviate hypoxia globally, how local oxygen levels change is not known because of the inability to longitudinally assess vascular ...
Rakesh K. Jain, Dai Fukumura, Timothy P. Padera, Edward B. Brown, Dan G. Duda, Moungi G. Bawendi, Triantafyllos Stylianopoulos, Hang Lee, Hee-Sun Han, Walid S. Kamoun, Ahmed S. Mousa, Margaret R. Martin, Vikash P. Chauhan, Ryan M. Lanning, John D. Martin   +14 more
openaire   +1 more source

Supplementary Data from Multiphoton Phosphorescence Quenching Microscopy Reveals Kinetics of Tumor Oxygenation during Antiangiogenesis and Angiotensin Signaling Inhibition

, 2023
Supplementary Data from Multiphoton Phosphorescence Quenching Microscopy Reveals Kinetics of Tumor Oxygenation during Antiangiogenesis and Angiotensin Signaling ...
Rakesh K. Jain, Dai Fukumura, Timothy P. Padera, Edward B. Brown, Dan G. Duda, Moungi G. Bawendi, Triantafyllos Stylianopoulos, Hang Lee, Hee-Sun Han, Walid S. Kamoun, Ahmed S. Mousa, Margaret R. Martin, Vikash P. Chauhan, Ryan M. Lanning, John D. Martin   +14 more
openaire   +1 more source

Towards Water Soluble Mitochondria-Targeting Theranostic Osmium(II) Triazole-Based Complexes

Molecules, 2016
The complex [Os(btzpy)2][PF6]2 (1, btzpy = 2,6-bis(1-phenyl-1,2,3-triazol-4-yl)pyridine) has been prepared and characterised. Complex 1 exhibits phosphorescence (λem = 595 nm, τ = 937 ns, φem = 9.3% in degassed acetonitrile) in contrast to its known ...
Salem A. E. Omar, Paul A. Scattergood, Luke K. McKenzie, Helen E. Bryant, Julia A. Weinstein, Paul I. P. Elliott   +5 more
doaj   +1 more source

Oxygenation through oral Ox66 in a two-hit rodent model of respiratory distress

Artificial Cells, Nanomedicine, and Biotechnology
Acute respiratory distress syndrome (ARDS) is a complication of pulmonary disease that produces life-threatening hypoxaemia. Despite ventilation and hyperoxic therapies, undetected hypoxia can manifest in capillary beds leading to multi-organ failure ...
Bjorn K. Song, Danuel A. Carr, Erica D. Bruce, William H. Nugent   +3 more
doaj   +1 more source

Efficient triplet exciton phosphorescence quenching from a rhenium monolayer on silicon

Journal of Materials Chemistry C
Using phosphorescence lifetime image microscopy (PLIM) measurements we report up to 95% efficient triplet exciton energy transfer from a rhenium(i) fac-tricarbonyl bipyridine complex deposited as a Langmuir–Blodgett monolayer to crystalline silicon.
W. Banks, Michael P. Coogan, T. Markvart, L. Danos   +3 more
semanticscholar   +1 more source

[Imaging of In Vivo Oxygen Tension Based on Phosphorescence Lifetime Microscopy].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
Molecular oxygen plays essential roles in aerobic organisms as a terminal electron acceptor in the electron transport chain in mitochondria. The intracellular oxygen concentration of the entire body is strictly regulated by a balance between the supply ...
Toshitada Yoshihara
semanticscholar   +1 more source

Frequency Multiplexed In Vivo Multiphoton Phosphorescence Lifetime Microscopy

Nature Photonics, 2012
Multiphoton microscopy (MPM) is widely used in vivo for optical sectioning deep inside scattering tissue1,2. Phosphorescence lifetime imaging microscopy (PLIM)3 is a powerful technique for obtaining biologically relevant chemical information through ...
S. Howard, A. Straub, N. Horton, D. Kobat, Chris Xu   +4 more
semanticscholar   +1 more source

Harnessing the Orientation of Columnar Discotic Liquid Crystals for Narrowband Blue Emission with Enhanced Out‐Coupling Efficiency Toward Improvement of SP‐OLEDs Performance

Advanced Functional Materials, EarlyView.
Solution‐processed OLEDs containing discotic liquid‐crystalline MR‐TADF emitters are reported. Supramolecular self‐assembly induces homeotropic columnar alignment, enforcing preferential horizontal orientation of the emitter transition dipole moment in spin‐coated films, which leads to an enhancement in the device light outcoupling efficiency while ...
Joydip De, Abhishek Kumar Gupta, Džiugas Litvinas, Francisco Tenopala‐Carmona, Matthias Lehmann, Malte C. Gather, Eli Zysman‐Colman   +6 more
wiley   +1 more source

Thermally Activated Delayed Fluorescence in Phase‐Separated Nanostructures

Advanced Functional Materials, EarlyView.
A supramolecular, phase‐separation driven strategy yields charge transfer (CT) complexes from alternating electron‐deficient pyromellitic diimide and electron‐rich 4,5‐dibromoveratrole. The resulting CT complexes self‐assemble into lamellar nanosheets with nanometer‐sized domains that exhibit thermally activated delayed fluorescence (TADF) at room ...
Bart W.L. van den Bersselaar, Giovanni M. Beneventi, Philip M. Greißel, Lukas A. Mai, Stefan J. D. Maessen, Bas F.M. de Waal, E.W. Meijer, Dirk M. Guldi, Ghislaine Vantomme   +8 more
wiley   +1 more source