Results 21 to 30 of about 2,907 (91)

Unveiling the Immunopharmacological Mechanisms of Biejiajian Pills (BJJP) Underlying the Treatment of Hepatic Fibrosis: Insights From Network Pharmacology and Experimental Validation

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
This study employed an integrated workflow combining network pharmacology, machine learning, molecular docking, UHPLC‐HRMS, and in vivo validation. The core design aimed to identify key compounds and signature genes of BJJP against HF, explore their immune‐related mechanisms, and verify the therapeutic targets and pathways through experimental ...
Chan Mo, Zhuolin Wei, Jinnan He, Yuan Liu, Jiaorong Zheng, Min Hong, Yuhong Song   +6 more
wiley   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, Volume 13, Issue 11, 23 February 2026.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Beer Production With Umbu (Spondias tuberosa) Using Conventional and Nonconventional Yeast

Journal of Food Science, Volume 91, Issue 1, January 2026.
ABSTRACT This study evaluated the fermentation performance and bioactive properties of beers produced by Pichia kluyveri L131 and commercial Saccharomyces pastorianus, individually and in coculture, in wort enriched with umbu pulp. Fermentation profiles were assessed over 12 days, focusing on yeast population dynamics, carbohydrate consumption, and ...
Diego Pádua de Almeida, Hygor Lendell Silva de Souza, Ana Luiza Dozol, Mariana Moysés Delorme, Vanessa Naciuk Castelo‐Branco, Adriene Ribeiro Lima, Alexandre Soares dos Santos, Nadia Nara Batista, Rosane Freitas Schwan, Gustavo Molina, Cintia Lacerda Ramos   +10 more
wiley   +1 more source

The Interplay between the Gut and Ketogenic Diets in Health and Disease

Advanced Science, Volume 12, Issue 36, September 25, 2025.
This review synthesizes current knowledge on the interaction between ketogenic diets and the gut, covering gut physiology, intestinal immunity, and the gut microbiome. It explores innovative methods for tailoring the diet to maximize benefits while reducing side effects. Emphasis is placed on gut‐mediated mechanisms as a critical interface between diet
Chunlong Mu, Jong M. Rho, Jane Shearer
wiley   +1 more source

The GmGDPD family regulates phosphorus efficiency in soybean and enables precision breeding with domestication‐lost alleles

The Plant Genome, Volume 18, Issue 3, September 2025.
Abstract Phosphorus (P) deficiency severely limits soybean productivity, yet the genetic basis of P efficiency remains underexplored. Here, we systematically identified 27 GmGDPD genes in soybean (Glycine max), revealing that family expansion was driven by segmental/tandem duplication events, accompanied by functional diversification through ...
Huifang Zuo, Huanhuan Gao, Mengying Huo, Mengshi He, Mengjun Xu, Lina Zhang, Qiqi Huang, Haiyan Lü, Shanshan Chu, Erhui Xiong, Jinying Li, Dandan Hu, Dan Zhang   +12 more
wiley   +1 more source

A Hypothesis: Metabolic Contributions to 16p11.2 Deletion Syndrome

BioEssays, Volume 47, Issue 3, March 2025.
16p11.2 Deletion syndrome is associated with brain, body, and behavioral symptoms. A majority of 16p11.2 genes relate to metabolism, involving amino acids/proteins, DNA, RNA, catabolism, lipids, and carbohydrates. Additional contributions include changes in cell structure, signaling, development, immune system, nervous system, and localization.
Brandon Kar Meng Choo, Sarah Barnes, Hazel Sive   +2 more
wiley   +1 more source

Genome‐wide association mapping reveals novel genes and genomic regions controlling root‐lesion nematode resistance in chickpea mini core collection

The Plant Genome, Volume 18, Issue 1, March 2025.
Abstract Root‐lesion nematodes (RLN) pose a significant threat to chickpea (Cicer arietinum L.) by damaging the root system and causing up to 25% economic losses due to reduced yield. Worldwide commercially grown chickpea varieties lack significant genetic resistance to RLN, necessitating the identification of genetic variants contributing to natural ...
Ashish Kumar, Yogesh Dashrath Naik, Vedant Gautam, Sunanda Sahu, Vinod Valluri, Sonal Channale, Jayant Bhatt, Stuti Sharma, R. S. Ramakrishnan, Radheshyam Sharma, Himabindu Kudapa, Rebecca S. Zwart, Somashekhar M. Punnuri, Rajeev K. Varshney, Mahendar Thudi   +14 more
wiley   +1 more source

The Food Contaminants Chloropropanols and Chloropropanol Esters: A Review

Journal of Food Biochemistry, Volume 2025, Issue 1, 2025.
Chloropropanols and chloropropanol esters are major food pollutants. Free chloropropanols are found in foods such as soy sauce, infant formula, edible vegetable oils, bread and margarine, whereas chloropropanol esters are found primarily in processed oils and fats.
Jinghui Fan, Jingnan Zhang, Xin Gao, Yang Zhou, Charalampos Proestos   +4 more
wiley   +1 more source

The genome‐wide response of Dermatophagoides pteronyssinus to cystatin A, a peptidase inhibitor from human skin, sheds light on its digestive physiology and allergenicity

Insect Molecular Biology, Volume 33, Issue 6, Page 662-677, December 2024.
The genome of Dermatophagoides pteronyssinus was screened for genes encoding peptidases (n = 320), glycosylases (n = 77), lipases and esterases (n = 320), peptidase inhibitors (n = 65) and allergen‐related proteins (n = 52). Ingestion of cystatin A caused the regulation of cysteine endopeptidases and glycosylases, genes acquired by horizontal gene ...
José Cristian Vidal‐Quist, Félix Ortego, Stephane Rombauts, Pedro Hernández‐Crespo   +3 more
wiley   +1 more source

Biological implications and therapeutic potential of phosphodiesterase inhibitors: A review. [PDF]

Medicine (Baltimore)
Alnazari M, Bakhsh A, Abdullah S, Al Qahtani S, Borhan W, Rajih E, Alshehri AM.   +6 more
europepmc   +1 more source