Results 101 to 110 of about 3,382 (177)

Continuous Imaging of the Cardiac Cycle Metabolism With Hyperpolarized [1‐13C]Pyruvate

open access: yesNMR in Biomedicine, Volume 39, Issue 11, November 2026.
We present a continuous hyperpolarized 13C MRI framework for phase‐resolved imaging of myocardial metabolism throughout the entire cardiac cycle. By combining spectral‐spatial bicarbonate excitation with frequency‐shifted reconstruction of residual pyruvate signal, both metabolites are obtained from a single acquisition.
Mohsen Redda   +5 more
wiley   +1 more source

Biosynthesis and Genetic Tuning of Guanine Crystals via Metabolic Engineering of Yeast

open access: yesAngewandte Chemie, Volume 138, Issue 40, 28 September 2026.
We demonstrate how yeast cells can be harnessed as cellular factories for the synthesis of optically functional guanine crystals, where genetic editing is used to tune crystal size, order and optical properties. This demonstrates a powerful new biosynthetic approach for the development of sustainable and biocompatible optical pigments, which utilizes ...
Jerome N. Janssen   +11 more
wiley   +2 more sources

The GH130 family of mannoside phosphorylases contains glycoside hydrolases that target beta-1,2 mannosidic linkages in Candida mannan

open access: yes, 2015
The depolymerization of complex glycans is an important biological process that is of considerable interest to environmentally relevant industries. Bêta-mannose is a major component of plant structural polysaccharides and eukaryotic N-glycans.
Baslé, Arnaud   +4 more
core   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, Volume 20, Issue 10, Page 2466-2489, October 2026.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Effects of Roasting on the Antioxidant and Lipid‐Modulating Activities of Argania spinosa Oil Under Diabetic Conditions

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
Roasted and non‐roasted Argania spinosa seed oils were evaluated in streptozotocin‐induced diabetic rats. Biochemical and histopathological analyses assessed glucose regulation, lipid metabolism, oxidative stress, liver enzymes, glycogen content, and tissue architecture.
Nour Elhouda Daoudi   +9 more
wiley   +1 more source

Thermostable alpha-glucan phosphorylases : characteristics and industrial applications

open access: yes, 2018
alpha-Glucan phosphorylases (alpha-GPs) catalyze the reversible phosphorolysis of alpha-1,4-linked polysaccharides such as glycogen, starch, and maltodextrins, therefore playing a central role in the usage of storage polysaccharides.
Ubiparip, Zorica   +4 more
core   +1 more source

Turning up the heat: Can thermal therapy really protect muscle health in older adults?

open access: yes
Experimental Physiology, EarlyView.
Franck Brocherie   +2 more
wiley   +1 more source

A Post–NGP Mitsuokella jalaludinii as a Therapeutic Candidate for Gout

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Schematic summary of the therapeutic mechanisms and evaluation of the post–NGP strain M. jalaludinii PMC73 for gout. PMC73 demonstrated uric acid–lowering efficacy through purine catabolism and hypoxanthine utilization, along with intracellular uric acid reduction in macrophages.
Mohammed Solayman Hossain   +13 more
wiley   +1 more source

Triazole‐Linked Pyrimidine Nucleoside Dimers: Design, Synthesis, and Applications in Medicinal and Nucleic Acid Chemistry. Part IV

open access: yesChemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
A series of 18 pyrimidine nucleoside dimers analogues with a short 1,4‐disubstituted 1,2,3‐triazole linkage were synthesized using a click chemistry approach (CuAAC). Analysis of the obtained products was conducted utilizing 1D/2D NMR spectroscopy (1H, 13C, 19F, 15N, and 29Si), mass spectrometry (ESI‐MS), and high‐performance liquid chromatography ...
Dagmara Baraniak   +2 more
wiley   +1 more source

MOESM2 of In vitro and in vivo exploration of the cellobiose and cellodextrin phosphorylases panel in Ruminiclostridium cellulolyticum: implication for cellulose catabolism

open access: yes, 2019
Additional file 2. Sequence alignment of all modeled phosphorylases CdpA, CdpB, CdpC and CbpA from R. cellulolyticum and C. thermocellum cellodextrin phosphorylase (5NZ8).
Clara Kampik (7341998)   +7 more
core   +1 more source

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