Results 111 to 120 of about 3,382 (177)

Efficient whole-cell biocatalytic synthesis of 2′-deoxy-2′-fluoroadenosine, a key building block for nucleic acid drugs

Synthetic and Systems Biotechnology
2′-Deoxy-2′-fluoroadenosine (2′-F-dA) is a nucleoside analogue used as a key building block for oligonucleotide drugs. It can be biosynthesized from a low-cost 2′-deoxy-2′-fluorouridine via one-pot transglycosylation catalyzed by a thymidine ...
Dandan Feng, Tianshu Zhang, Guan Zhou, Yanli Cao, Quan Luo, Huifang Xu, Xuefeng Lu   +6 more
doaj   +1 more source

Pleural Mesothelioma With Unusual Squamous Differentiation: A Clinicopathological Case Report With Molecular Insights From Whole‐Exome Sequencing

Pathology International, Volume 76, Issue 10, October 2026.
This case report highlights a rare histological variant of pleural mesothelioma with partially squamous differentiation in an 81‐year‐old man with occupational asbestos exposure. In addition to histological, immunohistochemical and fluorescence in situ hybridization analyses, indicating a common mesothelial origin of both tumor components, whole‐exome ...
Julius Bodemeyer, Mara Elisa Mierzwa, Jörg Seraphin, Rizkallah Maroun, Wolfgang Körber, Christoph Engelke, Felix Bremmer, Tessa Rosenthal, Tim Heißenberg, Kirsten Reuter‐Jessen, Philipp Ströbel, Alexander Marx, Hanibal Bohnenberger   +12 more
wiley   +1 more source

Exploring glycoside phosphorylases for the production of functional carbohydrates and glycosides

, 2022
Carbohydrates are omnipresent molecules with a somewhat negative reputation since the conventional high carbohydrate diet can increase the risk of obesity and related chronic diseases.
Ubiparip, Zorica
core  

Use of specific glycoside phosphorylases for the implementation of phosphorolysis or reverse phosphorolysis reactions

, 2014
Use of specific glycoside phosphorylases for the implementation of phosphorolysis or reverse phosphorolysis ...
Veronese, Gabrielle, Henrissat, Bernard, Laville, Elisabeth, Monsan, Pierre, Ladeveze, Simon, Tarquis, Laurence   +5 more
core  

Structure-functional studies of bacterial glycoside phosphorylases

, 2010
Disaccharide phosphorylases are interesting enzymes for use in glycoside synthesis since they pose a number of advantages over glycoside hydrolases and glycosyltransferases, enzymes more traditionally used for this purpose: they require no expensive ...
Van Hoorebeke, Annelies
core  

Galactosylation reactions catalyzed by disaccharide phosphorylases

, 2012
Galactosylation, as one of the main types of glycosylation reactions, is of particular importance both in vivo and in vitro. The goal of this PhD research is to explore and exploit galactosylation reactions catalyzed by disaccharide phosphorylases.
Chen, Chao
core  

Diversification of 4′-Methylated Nucleosides by Nucleoside Phosphorylases

The growing demand for 4′-modified nucleoside analogs in medicinal and biological chemistry is contrasted by the challenging synthetic access to these molecules and the lack of efficient diversification strategies.
Gert Bange (811040), Daniel B. Werz (1393828), Patrick Pausch (811039), Anett Schallmey (1418380), Christoph Köllmann (4824759), Peter Neubauer (1754), Margarita Seeger (11284329), Sarah Westarp (11284332), Sebastian Kemper (2383831), Felix Kaspar (8176371), Anna P. Lehmann (11284335), Anke Kurreck (10755533)   +11 more
core   +1 more source

Oligomeric Symmetry of Purine Nucleoside Phosphorylases

Many enzymes are composed of several identical subunits, which are arranged in a regular fashion and usually comply with some definite symmetry. This symmetry may be approximate or exact and may or may not coincide with the symmetry of crystallographic ...
Boris Gomaz, Zoran Štefanić
core   +1 more source

Two purine nucleoside phosphorylases in Bacillus subtilis. Purification and some properties of the adenosine-specific phosphorylase.

, 1978
Udgivelsesdato: 1978 AugTwo purine nucleoside phosphorylases (purine-nucleoside:orthophosphate ribosyltransferase, EC 2.4.2.1) were purified from vegetative Bacillus subtilis cells.
Jensen, Kaj Frank
core   +1 more source

Late Stage Mannan Metabolism in Cellvibrio japonicus Requires the Combined Action of a Mannosyl-Glucose Phosphorylase and a Mannobiose Epimerase. [PDF]

Mol Microbiol
Novak JK, Gardner JG.
europepmc   +1 more source