Results 261 to 270 of about 1,642,696 (345)
GLUCOSE PHOSPHORYLATION AND OXIDATION IN CELL-FREE TISSUE EXTRACTS
Sidney P. Colowick +2 more
openalex +1 more source
Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng +10 more
wiley +1 more source
PTPN22-CD45 dual phosphatase retrograde feedback enhances TCR signaling and autoimmunity. [PDF]
Yang S +20 more
europepmc +1 more source
A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers +10 more
wiley +1 more source
The Hippo signaling pathway as a therapeutic target in Alzheimer's disease. [PDF]
Chen D +2 more
europepmc +1 more source
PHOSPHORYLATION OF MONOACETONE ADENOSINE AND OF DIACETYL ADENOSINE
P.A. Levene, R. Stuart Tipson
openalex +1 more source
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee +12 more
wiley +1 more source
STK-mediated FadR phosphorylation regulates the acid resistance and virulence of Streptococcus suis. [PDF]
Li S +6 more
europepmc +1 more source
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar +6 more
wiley +1 more source

