Results 281 to 290 of about 2,046,842 (395)

Manganese mediates antiviral effects by driving an ATM -TBK1 phosphorylation signaling pathway. [PDF]

Front Immunol
Sui H, Wiscovitch-Russo R, Cachaco S, Yang J, Bruchey W, Laverdure S, Chen Q, Imamichi T.   +7 more
europepmc   +1 more source

Extracellular vesicles from hiPSC-derived NSCs protect human neurons against Aβ-42 oligomers induced neurodegeneration, mitochondrial dysfunction and tau phosphorylation [PDF]

Shama Rao, Leelavathi N. Madhu, Roshni Sara Babu, Goutham Shankar, Sanya Kotian, Advaidhaa Nagarajan, Raghavendra Upadhya, Esha Narvekar, James J. Cai, Ashok K. Shetty   +9 more
openalex   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

FSH-Induced Nuclear Exclusion of FOXO1 Mediated by PI3K/Akt Signaling Pathway in Granulosa Cells Is Associated with Follicle Selection and Growth of the Hen Ovary. [PDF]

Cells
Yan C, Ou Y, Sun X, Sun Y, Zhao J, Qin N, Xu R.   +6 more
europepmc   +1 more source

Suppression of Vimentin Phosphorylation by the Avian Reovirus p17 through Inhibition of CDK1 and Plk1 Impacting the G2/M Phase of the Cell Cycle

, 2016
Hung‐Chuan Chiu, Wei‐Ru Huang, Tsai‐Ling Liao, Hung‐Yi Wu, Muhammad Munir, Wing-Ling Shih, Hung‐Jen Liu   +6 more
openalex   +2 more sources

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Research advances in epigenetic modifications and post-translational modifications in endothelial-mesenchymal transition. [PDF]

Epigenetics Chromatin
Shen Z, Yang S, Zhang Q, Liu Q, Wang H, Tao J, Li Z, Wang C, Nie Y, Xu X, Guo H, Cui L.   +11 more
europepmc   +1 more source

A quantitative atlas of mitotic phosphorylation

Proceedings of the National Academy of Sciences of the United States of America, 2008
Noah E. Dephoure, Chunshui Zhou, J. Villén, S. Beausoleil, C. Bakalarski, S. Elledge, S. Gygi   +6 more
semanticscholar   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Survival strategies of mycoplasmas: the critical role of post-translational modifications. [PDF]

Front Cell Infect Microbiol
Li T, Yuan H, Zhang W, Guo F.
europepmc   +1 more source