Results 31 to 40 of about 107,533,269 (165)
Altered expression of genes involved in the serine synthesis pathway (SSP) in patients with acute myeloid leukemia [PDF]
Journal of Kerman University of Medical SciencesBackground: Acute myeloid leukemia (AML) is characterized by the uncontrolled proliferation of malignant cells, which rely on various metabolic pathways to sustain their survival and growth.
Parinaz Khadem +4 more
doaj +1 more source
Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome
Frontiers in Molecular Biosciences, 2021 Background: Fragile X-associated tremor/ataxia syndrome (FXTAS) is an adult-onset neurodegenerative disorder associated with premutation CGG-repeat expansions (55–200 repeats) in the 5′ non-coding portion of the fragile X mental retardation 1 (FMR1) gene.
Katharine Nichole Holm +14 more
doaj +1 more source
Amino Acid and Lipid Metabolism in Cancer: Mechanisms and Therapeutic Opportunities. [PDF]
MedComm (2020)Amino Acid and lipid metabolism in cancer: (A) Regulation of Amino acid transportation and metabolism in cancer. (B) The core organization of lipid metabolic reprogramming in cancer and their functional consequences. ABSTRACT Metabolic reprogramming is a defining feature of cancer and a major contributor to immune escape.
Wang Z, Fu X, Bai J, Liu Y, Huang K.
europepmc +2 more sources
Expressions and roles of key enzymes in serine synthesis pathway in NaAsO2-treated HaCaT cells
环境与职业医学, 2022 BackgroundThe key enzymes of serine synthesis pathway (SSP) play an important role in tumor growth, proliferation, and invasion, but their roles in arsenic carcinogenesis are unclear.ObjectiveTo observe the effects of NaAsO2 treatment on the expressions ...
Fengmin LI +5 more
doaj +1 more source
Scientific Reports, 2020 Phosphoenolpyruvate carboxykinase (PEPCK) is a gluconeogenic enzyme with a cytosolic (Pck1/PEPCK-C) and mitochondrial (Pck2/PEPCK-M) isoform. Here we investigate the effect of 3-mercaptopicolinic acid (3-MPA), a PEPCK inhibitor, on C2C12 muscle cells. We
Madelaine C. Brearley +4 more
doaj +1 more source
Transcriptome analysis of primary human oral keratinocytes stimulated with Prevotella melaninogenica
口腔疾病防治, 2022 Objective To investigate the transcriptomic changes in primary human oral keratinocytes (pHOKs) after coculture with Prevotella melaninogenica (P.m) and to verify the changes in human oral keratinocyte (HOK) cell lines.
GUO Yiting +4 more
doaj +1 more source
Targeting PSAT1 to mitigate metastasis in tumors with p53-72Pro variant
Signal Transduction and Targeted Therapy, 2023 The single-nucleotide polymorphism (SNP) of p53, in particular the codon 72 variants, has recently been implicated as a critical regulator in tumor progression. However, the underlying mechanism remains elusive.
Jingwen Jiang +14 more
doaj +1 more source
Structural Analysis of a Putative Phosphoserine Aminotransferase from C.Hutchinsonii
, 2015 Structural analysis results for a putative phosphoserine aminotransferase from Cytophaga Hutchinsonii.
Saman Ehsan (645533)
core +1 more source
An integrated pan-cancer analysis of PSAT1: A potential biomarker for survival and immunotherapy
Frontiers in Genetics, 2022 Phosphoserine aminotransferase 1 (PSAT1) may be an oncogene that plays an important role in various cancer types. However, there are still many gaps in the expression of PSAT1 gene and its biological impact in different types of tumors.
Mingtao Feng +10 more
doaj +1 more source
, 2011 Copyright information:Taken from "Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells"http://www.molecular-cancer.com/content/7/1/14Molecular Cancer 2008;7():14-14.Published ...
Céline Gongora (86934) +12 more
core +1 more source