Results 71 to 80 of about 107,533,269 (165)

Engineering a Synthetic Formatotrophic Yeast With Enhanced Growth Capacity on Formate

open access: yesAdvanced Energy and Sustainability Research, Volume 7, Issue 5, May 2026.
Engineering Yeast for Growth on Formate and Methanol via Serine‐Centered C1 Coupling. By engineering serine metabolism and remodeling the rGly pathway, we rendered yeast growth strictly dependent on formate. This synthetic formatotrophy enables growth on dual‐C1 substrates by channeling formate into the central metabolism via serine deaminases and ...
Shuyuan Guo   +11 more
wiley   +1 more source

Cooperativity of Glucocorticoid Response Elements Located Far Upstream of the Tyrosine Aminotransferase Gene [PDF]

open access: yes, 1987
Two glucocorticoid response elements (GREs) located 2.5 kb upstream of the transcription initiation site of the tyrosine aminotransferase gene were identified by gene transfer experiments and shown to bind to purified glucocorticoid receptor.
Strähle, Uwe   +7 more
core   +1 more source

PSAT1 regulates hair follicle growth and stem cell behavior in cashmere goats

open access: yesBMC Veterinary Research
Background The Arbas Cashmere Goat from Inner Mongolia is renowned for its superior-quality cashmere, which is primarily produced by secondary hair follicles (SHFs).
Xiao-yu Han   +11 more
doaj   +1 more source

A Novel Multimodal LC–MS/MS Panel for the Comprehensive Diagnosis of Neurometabolic Disorders in CSF

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Metabolic testing of cerebrospinal fluid (CSF) is essential for early diagnosis of neurometabolic disorders. However, the large number of differential diagnoses, the phenotypic variance within a clinical picture, and the disease rarity complicate targeted metabolic diagnostics.
Stine Christ   +8 more
wiley   +1 more source

Mapping the effects of specific radiation damage and solvent radiolysis in buffers and crystals with online UV–Vis absorption spectroscopy

open access: yesActa Crystallographica Section D, Volume 82, Issue 5, Page 504-515, May 2026.
Radiation‐induced changes during X‐ray crystallographic data collection can compromise concurrent spectroscopic studies. Suitable protocols to detect and identify spectral artefacts from crystallization buffers and cryoprotectants are essential for the reliable analysis of chromophoric ligands in macromolecules.Online UV–Vis absorption spectroscopy is ...
Jack Stubbs   +8 more
wiley   +1 more source

Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells-6

open access: yes, 2011
Copyright information:Taken from "Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells"http://www.molecular-cancer.com/content/7/1/14Molecular Cancer 2008;7():14-14.Published ...
Céline Gongora (86934)   +12 more
core   +1 more source

Cysteine biosynthesis in trichomonas vaginalis involves cysteine synthase utilizing o-phosphoserine

open access: yes, 2006
Trichomonas vaginalis is an early divergent eukaryote with many unusual biochemical features. It is an anaerobic protozoan parasite of humans that is thought to rely heavily on cysteine as a major redox buffer, because it lacks glutathione.
Coombs, G.H.   +3 more
core   +3 more sources

Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells-0

open access: yes, 2011
Copyright information:Taken from "Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells"http://www.molecular-cancer.com/content/7/1/14Molecular Cancer 2008;7():14-14.Published ...
Céline Gongora (86934)   +12 more
core   +1 more source

Chromatin Structures of the Rat Tyrosine Aminotransferase Gene Relate to the Function of Its cis-Acting Elements [PDF]

open access: yes, 1990
The relationship between DNase I-hypersensitive sites (HSs) and transcriptional enhancers of the rat tyrosine aminotransferase (TAT) gene was examined by comparing HSs in and around the TAT gene with the activity of the corresponding DNA sequences in ...
Boshart, Michael   +5 more
core   +1 more source

Curcuminoid supplementation alters proteomic profiles and clinical outcomes in canine primary epilepsy: A pilot study

open access: yesVeterinary and Animal Science
Background: In dogs, primary epilepsy syndrome (PES) requires lifelong pharmacological management. Curcuminoids possess anti-inflammatory and antioxidant properties with potential neuroprotective effects.
Boonrat Chantong   +6 more
doaj   +1 more source

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