Results 91 to 100 of about 107,533,269 (165)

Histone lactylation-boosted AURKB facilitates colorectal cancer progression by inhibiting HNRNPM-mediated PSAT1 mRNA degradation

Journal of Experimental & Clinical Cancer Research
Background Aurora kinase B (AURKB), a key regulator of mitosis, is frequently upregulated in various malignancies, including colorectal cancer (CRC), and is associated with poor prognosis.
Yuyi Li, Jinjin Peng, Di Wu, Qingxin Xie, Yichao Hou, Linjing Li, Xintian Zhang, Yu Liang, Jing Feng, Jiaqing Chen, Wangshuang Chen, Che Xu, Han Yao, Xiangjun Meng   +13 more
doaj   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

Effect of 5mM PBA on the expression of thapsigargin-inducible (ER-stress) genes in C2C12 myotubes.

, 2018
(A) mRNA abundance of Phosphoserine aminotransferase 1 (PSAT1), Phosphoserine phosphatase (PSPH), 3-Phosphoglycerate dehydrogenase (PHGDH), asparagine synthetase (ASNS), mitochondrial phosphoenolpyruvate carboxykinase (PCK2), Activating transcription ...
Zoe C. T. R. Daniel (5566262), Tim Parr (668636), Francis J. P. Ebling (160811), Madelaine C. Brearley (5566265), Jo E. Lewis (3779404), Sarah Jones (400393), David M. Brown (475802), John M. Brameld (668635)   +7 more
core   +1 more source

LMTK3 regulation of EV biogenesis and cargo sorting promotes tumour growth by reducing monocyte infiltration and driving pro-tumourigenic macrophage polarisation in breast cancer

Molecular Cancer
Background Lemur Tail Kinase 3 (LMTK3) promotes cell proliferation, invasiveness and therapy resistance, and its expression correlates with poor survival in several different malignancies, including breast cancer. Crosstalk through extracellular vesicles
Mark Samuels, Christos Karakostas, Simoni Besta, Andrea Lauer Betrán, Katerina Tsilingiri, Charlotte Turner, Reza Shirazi Nia, Niloufar Poudine, Richard Goodyear, William Jones, Apostolos Klinakis, Georgios Giamas   +11 more
doaj   +1 more source

Human L-3-phosphoserine phosphatase: sequence, expression and evidence for a phosphoenzyme intermediate

, 1997
We report the sequence of the cDNA encoding human L-3-phosphoserine phosphatase. The encoded polypeptide contains 225 residues and shows 30% sequence identity with the Escherichia coli enzyme.
Isabelle Gerin, Jean-François Collet, Mark H Rider, Emile Van Schaftingen, Veiga-da-Cunha, Maria, Gerin, Isabelle, Collet, Jean-François, Van Schaftingen, Emile, Maria Veiga-da-Cunha, Rider, Mark   +9 more
core   +1 more source

Structural and Mechanistic Studies of Phosphoserine Aminotransferase

, 2015
Phosphoserine aminotrasferase (PSAT: EC 2.6.1.52) is a vitamin B6-dependent enzyme and a member of the subgroup IV in the aminotransferase superfamily.
Ali, Fawad
core  

Overexpression of Phosphoserine Aminotransferase (PSAT)-Enhanced Cadmium Resistance and Accumulation in Duckweed (Lemna turionifera 5511)

Cadmium (Cd) hampers plant growth and harms photosynthesis. Glutamate (Glu) responds to Cd stress and activates the Ca2+ signaling pathway in duckweed, emphasizing Glu’s significant role in Cd stress.
Yuanyuan Liu, Yumeng Jiang, Ziyang Qu, Wenqian Han, Yunwen Yang, Yuman He, Yiqi Yu, Wenqiao Wang, Lin Yang, Xu Ma, Qiqi Di, Yong Wang, Ximeng Luo   +12 more
core   +1 more source

Serine biosynthetic pathway inhibitors

The present invention relates to serine biosynthetic pathway inhibitors such as phosphoglycerate dehydrogenase inhibitors and phosphoserine aminotransferase 1 inhibitors, and to theses inhibitors for use as a medicament, more in particular for the ...
Corbet, Cyril, Ravez, Séverine, Frédérick, Raphaël, Spillier, Quentin, Feron, Olivier   +4 more
core  

NapR Regulates the Expression of Phosphoserine Aminotransferase SerC to Modulate Biofilm Formation and Resistance to Serine Stress of Mycobacteria

Mycobacterium tuberculosis is a formidable pathogen capable of establishing persistent infections within macrophages. To survive and thrive within the host environment, it has evolved intricate regulatory networks, including a diverse array of ...
Xiaocui Ling, Weihui Li, Minhao Guo, Yukuo Gou, Linzhao He, Zhun Li   +5 more
core   +1 more source

The effect of phosphoserine aminotransferase-1 dependent fluctuation on timing of embryonic stem cell differentiation

, 2016
학위논문 (박사)-- 서울대학교 대학원 : 의과학과, 2016. 8. 윤홍덕.Embryonic stem cells (ESCs) undergo coordinated epigenetic and metabolic changes to differentiate properly.
황인영
core