Results 31 to 40 of about 4,347 (134)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, Volume 599, Issue 23, Page 3417-3443, December 2025.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Structural and functional insights into Mimivirus ORFans [PDF]

, 2007
Background Mimivirus isolated from A. polyphaga is the largest virus discovered so far. It is unique among all the viruses in having genes related to translation, DNA repair and replication which bear close homology to eukaryotic genes.
Fischer, Daniel, Saini, Harpreet Kaur
core   +3 more sources

Structures of two LarA‐like nickel‐pincer nucleotide cofactor‐utilizing enzymes with a single catalytic histidine residue

Protein Science, Volume 34, Issue 12, December 2025.
Abstract The nickel‐pincer nucleotide (NPN) cofactor catalyzes the racemization/epimerization of α‐hydroxy acids in enzymes of the LarA family. The established proton‐coupled hydride transfer mechanism requires two catalytic histidine residues that alternately act as general acids and general bases. Notably, however, a fraction of LarA homologs (LarAHs)
Santhosh Gatreddi, Sundharraman Subramanian, Dexin Sui, Tianqi Wang, Julian Urdiain‐Arraiza, Benoît Desguin, Robert P. Hausinger, Kristin N. Parent, Jian Hu   +8 more
wiley   +1 more source

Unveiling the Potential of Lentilactobacillus hilgardii in Malolactic Fermentation: Comparative Genomics and Fermentation Dynamics

Microbial Biotechnology, Volume 18, Issue 12, December 2025.
This study explores the metabolic potential of Lentilactobacillus hilgardii for malolactic fermentation in winemaking. Genomic and in silico analyses, combined with experimental validation, reveal its resilience at low temperatures and unique enzymatic traits. Comparative insights with Oenococcus oeni highlight L.
Giacomo Mantegazza, Nicola Mangieri, Elnaz Vojoudi Yazdi, Pasquale Russo, Diego Mora, Giorgio Gargari   +5 more
wiley   +1 more source

On the enzymatic mechanism of 2-hydroxyisocaproyl-CoA dehydratase from Clostridium difficile [PDF]

, 2004
Die Gene ldhA und hadA aus Clostridium difficile (DSMZ 1296T) wurden kloniert und in Escherichia coli exprimiert. Die erhaltenen Proteine wurden gereinigt und als D-2-Hydroxyisocaproat-Dehydrogenase (LdhA) und 2-Hydroxyisocaproat-CoA-Transferase (HadA)
Buckel Wolfgang (Prof. Dr.), Kim Ji-Hoe
core   +1 more source

A Novel Agro‐Waste Formulated Medium Enhanced the Growth of Electrogenic Enterobacter Species Isolated Using Microbial Fuel Cell System: Response Surface Methodology Approach

Environmental Microbiology Reports, Volume 17, Issue 6, December 2025.
Electrogenic isolate, Enterobacter sp. DSAAI‐4 exhibited broad substrate range utilisation ability and high salt tolerance. Use of agro‐industrial waste barley bran for culture growth was promising and low cost. ABSTRACT Our study aims to identify electrogenic bacteria and optimise culture conditions using different commercial and agro‐industrial ...
Getachew Bantihun, Andualem Mekonnen, Venkata Kotakadi, Seid Mohammed   +3 more
wiley   +1 more source

The Gfr Uptake System Provides a Context‐Dependent Fitness Advantage to Salmonella Typhimurium SL1344 During the Initial Gut Colonization Phase

Molecular Microbiology, Volume 124, Issue 6, Page 507-520, December 2025.
Diet–microbiota interactions shape colonization resistance. While the microbiota restricts pathogens like Salmonella through nutrient competition, Salmonella can exploit private nutrients such as fructoselysine (FL), abundant in processed foods but inaccessible to most microbes.
Lea Fuchs, Cora Lisbeth Dieterich, Elena Melgarejo Ros, Philipp Keller, Anna Sintsova, Leanid Laganenka, Thomas A. Scott, Christopher Schubert, Shinichi Sunagawa, Julia A. Vorholt, Jörn Piel, Wolf‐Dietrich Hardt, Bidong D. Nguyen   +12 more
wiley   +1 more source

Bacterial fitness for plant colonization is influenced by plant growth substrate

New Phytologist, Volume 248, Issue 6, Page 3168-3190, December 2025.
Summary Despite advances in our understanding of bacterial plant colonization, the extent to which growth substrate influences the molecular mechanisms enabling bacteria to efficiently colonize plants remains poorly understood. To address this, we used randomly barcoded transposon mutagenesis sequencing (RB‐TnSeq) in Paraburkholderia graminis OAS925 ...
Marta Torres, Morgan N. Price, Albina Khasanova, Suzanne M. Kosina, Kateryna Zhalnina, Trent R. Northen, Adam M. Deutschbauer   +6 more
wiley   +1 more source

The structure and function of human brain hexokinase [PDF]

, 1996
An ATP binding site model for human brain hexokinase was established based on the similarity of the ATP-binding domains among actin, heat shock protein, glycerol kinase and brain hexokinase.
Zeng, Chenbo
core   +2 more sources

Simultaneous Knockout of Tk1‐SST and Tk1‐FFT via CRISPR/Cas9 Enhances the Natural Rubber Accumulation in Taraxacum kok‐saghyz

Plant Biotechnology Journal, Volume 23, Issue 12, Page 5654-5676, December 2025.
ABSTRACT Taraxacum kok‐saghyz (TKS) synthesises natural rubber (NR) and inulin using sucrose as a carbon source. However, molecular mechanisms regulating inulin and NR accumulation remain largely unclear. Here, we report the generation of double‐gene homozygous mutants, 1‐sst1‐fft, by simultaneously knocking out two key genes responsible for inulin ...
Bi Qin, Xue Hou, Songle Fan, Chuang Li, Xiaoxiao Wang, Qiuhui Chen, Yushuang Yang, Pin Lin, Liang RuiNan Lu, Canni Fu, Ning Yang, Qiaoli Gao, Shanshan Zheng, Shizhong Liu   +13 more
wiley   +1 more source