Lipid phosphate phosphatase 3 participates in transport carrier formation and protein trafficking in the early secretory pathway [PDF]
, 2013 The inhibition of phosphatidic acid phosphatase (PAP) activity by propanolol indicates that diacylglycerol (DAG) is required for the formation of transport carriers at the Golgi and for retrograde trafficking to the ER.
Alderton +77 more
core +2 more sources
Molecular fingerprints for a novel enzyme family in actinobacteria with glucosamine kinase activity [PDF]
, 2019 Actinobacteria have long been the main source of antibiotics, secondary metabolites with tightly controlled biosynthesis by environmental and physiological factors.
Empadinhas, N +4 more
core +1 more source
Nucleotide Sugars in Chemistry and Biology [PDF]
, 2022 Nucleotide sugars have essential roles in every living creature. They are the building blocks of the biosynthesis of carbohydrates and their conjugates.
Satu Mikkola
core +1 more source
Self-Resistance During Muraymycin Biosynthesis: A Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order [PDF]
, 2018 Muraymycins are antibacterial natural products from Streptomyces spp. that inhibit translocase I (MraY), which is involved in cell wall biosynthesis. Structurally, muraymycins consist of a 5′-C-glycyluridine (GlyU) appended to a 5″-amino-5″-deoxyribose ...
Cui, Zheng +8 more
core +2 more sources
Beyond protein modification: the rise of non-canonical ADP-ribosylation [PDF]
, 2022 ADP-ribosylation has primarily been known as post-translational modification of proteins. As signalling strategy conserved in all domains of life, it modulates substrate activity, localisation, stability or interactions, thereby regulating a variety of ...
Ahel, Ivan, Schuller, Marion
core +2 more sources
Molecular mechanism of dietary phospholipid requirement of Atlantic salmon, Salmo salar, fry [PDF]
, 2015 The phospholipid (PL) requirement in fish is revealed by enhanced performance when larvae are provided PL-enriched diets. To elucidate the molecular mechanism underlying PL requirement in Atlantic salmon, Salmo salar, were fed a minimal PL diet and ...
Carmona-Antoñanzas, Greta +3 more
core +1 more source
On the enzymatic mechanism of 2-hydroxyisocaproyl-CoA dehydratase from Clostridium difficile [PDF]
, 2004 Die Gene ldhA und hadA aus Clostridium difficile (DSMZ 1296T) wurden kloniert und in Escherichia coli exprimiert. Die erhaltenen Proteine wurden gereinigt und als D-2-Hydroxyisocaproat-Dehydrogenase (LdhA) und 2-Hydroxyisocaproat-CoA-Transferase (HadA)
Buckel Wolfgang (Prof. Dr.), Kim Ji-Hoe
core +1 more source
Singular Features of Trypanosomatids' Phosphotransferases Involved in Cell Energy Management [PDF]
, 2011 Trypanosomatids are responsible for economically important veterinary affections and severe human diseases. In Africa,Trypanosoma bruceicauses sleeping sickness or African trypanosomiasis, while in America,Trypanosoma cruziis the etiological agent of ...
Claudio A. Pereira +3 more
core +2 more sources
Glycomimicry: Display of the GM3 sugar epitope on Escherichia coli and Salmonella enterica sv Typhimurium [PDF]
, 2017 Oligosaccharides present on the surface of pathogenic bacteria play an important role in their interaction with their host. Bacteria with altered cell surface structures can be used to study these interactions, and glycoengineering represents a tool to ...
Aebi, Markus +4 more
core
Structure and function of enzymes involved in the anaerobic degradation of L-threonine to propionate [PDF]
, 2007 In Escherichia coli and Salmonella typhimurium, L-threonine is cleaved non-oxidatively to propionate via 2-ketobutyrate by biodegradative threonine deaminase, 2-ketobutyrate formate-lyase (or pyruvate formate-lyase), phosphotransacetylase and propionate ...
Chittori, Sagar +3 more
core +1 more source