Results 31 to 40 of about 9,938,953 (126)

Phage Display on the Anti-infective Target 1-Deoxy-d-xylulose-5-phosphate Synthase Leads to an Acceptor-Substrate Competitive Peptidic Inhibitor [PDF]

, 2017
Enzymes of the 2-C-methyl-d-erythritol-4-phosphate pathway for the biosynthesis of isoprenoid precursors are validated drug targets. By performing phage display on 1-deoxy-d-xylulose-5-phosphate synthase (DXS), which catalyzes the first step of this ...
Alessio Marcozzi, Hirsch, Anna Katharina Herta, Markus Fischer, Hirsch, Anna K. H., Fischer, Markus, Di Zhu, Anna K. H. Hirsch, Zhu, Di, Pesce, Diego, Herrmann, Andreas, Tiziana Masini, Diego Pesce, Boris Illarionov, Marcozzi, Alessio, Andreas Herrmann, Masini, Tiziana, Illarionov, Boris   +16 more
core   +1 more source

Recent and Promising Strategies for Robust, Sustainable, and Cost‐Friendly Production of Yogurt With Superior Quality

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT Yogurt is one of the most technologically mature fermented dairy products on the market, traditionally prepared using the two lactic acid bacteria (LAB) Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus. Global demand for yogurt continues to rise, driven by consumer interest in healthy, high‐protein diets with as few ...
Shuangqing Zhao, Belay Tilahun Tadesse, Christian Solem   +2 more
wiley   +1 more source

Mechanistic insights into HapC: A key enzyme in prodiginine biosynthesis in Hahella chejuensis

The FEBS Journal, Volume 293, Issue 17, Page 5303-5317, September 2026.
HapC catalyzes prodiginine biosynthesis through coordinated movements of its ATP‐binding, substrate‐binding, and catalytic‐swivel domains. The enzyme shows tolerance toward short‐chain MAP analogs, and docking analyses reveal key residues and structural features underlying its substrate flexibility.
Yueh‐Te Chan, Aden Dhana Rizkita, Hsin‐Ju Hsieh, Shu‐Fang Hsu, Tony Eight Lin, Wei‐Jan Huang, Kai‐Cheng Hsu, Sheila Nathan, Peiching Chang, Andrew H.‐J. Wang, Cheng‐Chung Lee   +10 more
wiley   +1 more source

Monitoring of uranium-phosphate biomineralisation with Serratia.

, 2015
(a) With glycerol phosphate as the electron donor and fumarate as the electron acceptor, increasing optical density and U mineral precipitation. Each point represents the average of three replicates with error bars ± 1 standard deviation.
Katherine Morris (634208), Jonathan. R. Lloyd (763473), Laura Newsome (763472)   +2 more
core   +1 more source

Titanium-containing bioactive phosphate glasses [PDF]

, 2012
The use of biomaterials has revolutionized the biomedical field and has received substantial attention in the last two decades. Among the various types of biomaterials, phosphate glasses have generated great interest on account of their remarkable ...
Knowles, Jonathan C., Kiani, Azadeh, Salih, Vehid, Newport, Robert J., Lakhkar, Nilay J., Smith, Mark E., Smith, M.E., Kiani, A., Hanna, John V., Knowles, J. C., Lakhkar, N.J., Knowles, J.C., Salih, V., Newport, R. J., Pickup, D.M., Pickup, D. M., Pickup, David M., Lakhkar, N. J., Hanna, J.V.   +18 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, Volume 600, Issue 15, Page 2154-2174, August 2026.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Stage‐Specific Metabolic and Proteomic Dynamics Underlying Ripening and Quality Formation in Tropical Evergreen Pomegranate

eFood, Volume 7, Issue 4, August 2026.
Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang, Ling Wei, Kaibing Zhou, Qin Deng, Muhammad Mobeen Tahir, Hongxia Wu, Minjie Qian   +6 more
wiley   +1 more source

Proposed mechanism for the conversion of 6PG to R5P.

, 2021
Oxidant could be an electron acceptor such as oxygen or Fe(III) generated in situ. X could be a lewis acid like Fe2+ or protonated amino group from the amino acid.
Julian L. Griffin (152780), Lukasz Szyrwiel (11306205), Gabriel Piedrafita (155328), Sreejith J. Varma (11790831), Cecilia Castro (538966), Christoph B. Messner (1295217), Markus Ralser (46782)   +6 more
core   +1 more source

Understanding of Molecular Mechanisms and Breeding Strategies for Enhancing Oleic Acid Biosynthesis in Oil Crops

Food Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Oleic acid (C18:1), a monounsaturated fatty acid, is a key determinant of nutritional value and oxidative stability of vegetable oils. Increasing its concentration has therefore become a central objective in oilseed crop improvement. This review summarizes current knowledge on the molecular mechanisms and breeding strategies underlying oleic ...
Muhammad Jawad Umer, Yuanxiao Zhu, Qing Lu, Hao Liu, Shaoxiong Li, Haifen Li, Runfeng Wang, Qianxia Yu, Yanbin Hong, Xuanqiang Liang, Lu Huang, Shengchun Zhang, Xiaoping Chen   +12 more
wiley   +1 more source

Enhanced Rice Yellow Mottle Virus Resistance via CRISPR/Cas9‐Targeted Mutagenesis of the Rice eIF(iso)4G Gene

Molecular Plant Pathology, Volume 27, Issue 7, July 2026.
Using CRISPR/Cas9 to edit the susceptibility gene in rice eIF(iso)4G helped to lower the infection of rice yellow mottle virus in mutated lines of the Indica rice cultivar IR2793‐80‐01. ABSTRACT Rice is a staple crop primarily recognised for its high content of carbohydrates and proteins.
Antony Kigaru, Elijah M. Ateka, Hanu R. Pappu, Everlyne M. Nganga, Rosemary Murori, Mary Esther Toili, Steven Runo   +6 more
wiley   +1 more source