Results 61 to 70 of about 1,180,081 (224)

Monitoring photodynamic therapy with photoacoustic microscopy [PDF]

Journal of Biomedical Optics, 2015
Abstract. We present our work on examining the feasibility of monitoring photodynamic therapy (PDT)-induced vasculature change with acoustic-resolution photoacoustic microscopy (PAM). Verteporfin, an FDA-approved photosensitizer for clinical PDT, was utilized.
Peng, Shao, David W, Chapman, Ronald B, Moore, Roger J, Zemp   +3 more
openaire   +2 more sources

Photoacoustic imaging of squirrel monkey cortical and subcortical brain regions during peripheral electrical stimulation

Photoacoustics, 2022
The investigation of neuronal activity in non-human primate models is of critical importance due to their genetic similarity to human brains. In this study, we tested the feasibility of using photoacoustic imaging for the detection of cortical and ...
Kai-Wei Chang, Yunhao Zhu, Heather M. Hudson, Scott Barbay, David J. Guggenmos, Randolph J. Nudo, Xinmai Yang, Xueding Wang   +7 more
doaj   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Photoacoustic shadow-casting microscopy

Optics Letters, 2019
We present photoacoustic shadow-casting microscopy (PASM), a technique that allows high-resolution imaging of weakly absorbing biological samples with unprecedented sensitivity. In PASM, a uniform optical absorbing layer is placed in contact with the samples and is excited by the light transmitted through the sample, producing photoacoustic (PA) waves ...
Jorge Tordera, Mora, Xiaohua, Feng, Liang, Gao   +2 more
openaire   +2 more sources

Photoacoustic microscopy of nanoparticles in cells and tissues [PDF]

, 2013
textMolecular photoacoustic imaging is an exciting new field that promises to visualize molecular indicators of disease. The objective of this dissertation is to progress molecular imaging by providing a photoacoustic microscopy platform to better ...
Cook, Jason Ray
core  

Easy Access to Experimental Bond Dissociation Energies in Solution Using 2D‐IR Spectroscopy

Angewandte Chemie, EarlyView.
How strong is a chemical bond? The answer is hidden in the spacing of vibrational levels. This anharmonic fingerprint yields the energy needed to break an X─H bond from a single measurement, turning an ultrafast observable into a thermochemical quantity directly in the solvent of interest.
Joseph Kölbel, Laurent Sévery, Ricardo J. Fernández‐Terán   +2 more
wiley   +2 more sources

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

Advanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu, Priyanka G. Bhosale, Vishal Kumar, Jeyrroy Gabriel, Shiyue Liu, Ciro Chiappini, Richard J. Cook, Mads S. Bergholt   +7 more
wiley   +1 more source

Photoacoustic microscopy in tissue engineering

Materials Today, 2013
Photoacoustic tomography (PAT) is an attractive modality for noninvasive, volumetric imaging of scattering media such as biological tissues. By choosing the ultrasonic detection frequency, PAT enables scalable spatial resolution with desired imaging depth up to ~7 cm while maintaining a high depth-to-resolution ratio of ~200 and consistent optical ...
Cai, Xin, Zhang, Yu Shrike, Xia, Younan, Wang, Lihong V.   +3 more
openaire   +4 more sources

Deconvolution-enhanced self-supervised learning for photoacoustic microscopy denoising

Journal of Innovative Optical Health Sciences
Optical-resolution photoacoustic microscopy is an emerging imaging technique that enables high-resolution visualization of biological structures. However, the presence of system noise significantly degrades image quality. As a key post-processing step in
Tingting Li, Jialin Li, Cailing Lin, Hongyang Zhao, Yifei Chen, Sung-Liang Chen, Mingjian Sun   +6 more
doaj   +1 more source