Results 81 to 90 of about 20,149 (224)

Super-resolution photoacoustic imaging via flow induced absorption fluctuations

, 2017
In deep tissue photoacoustic imaging the spatial resolution is inherently limited by the acoustic wavelength. We present an approach for surpassing the acoustic diffraction limit by exploiting temporal fluctuations in the sample absorption distribution ...
Arnal, Bastien, Bossy, Emmanuel, Chaigne, Thomas, Katz, Ori, Vilov, Sergey   +4 more
core   +3 more sources

Three-dimensional Optical-resolution Photoacoustic Microscopy [PDF]

Journal of Visualized Experiments, 2011
Optical microscopy, providing valuable insights at the cellular and organelle levels, has been widely recognized as an enabling biomedical technology. As the mainstays of in vivo three-dimensional (3-D) optical microscopy, single-/multi-photon fluorescence microscopy and optical coherence tomography (OCT) have demonstrated their extraordinary ...
Hu, Song, Maslov, Konstantin, Wang, Lihong V.   +2 more
openaire   +4 more sources

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Photoacoustic microscopy with meta-optics

Communications Physics
Recent advances in the miniaturization of optical elements have led to the emergence of imaging systems used for industrial and consumer-based applications.
Dorian S. H. Brandmüller, David Grafinger, Robert Nuster, Andreas Hohenau, Marcus Ossiander, Peter Banzer   +5 more
doaj   +1 more source

Multi-scale molecular photoacoustic tomography of gene expression.

PLoS ONE, 2012
Photoacoustic tomography (PAT) is a molecular imaging technology. Unlike conventional reporter gene imaging, which is usually based on fluorescence, photoacoustic reporter gene imaging relies only on optical absorption. This work demonstrates several key
Xin Cai, Li Li, Arie Krumholz, Zijian Guo, Todd N Erpelding, Chi Zhang, Yu Zhang, Younan Xia, Lihong V Wang   +8 more
doaj   +1 more source

Quickly Alternating Green and Red Laser Source for Real-time Multispectral Photoacoustic Microscopy

Photoacoustics, 2020
Multispectral photoacoustic microscopy uses a wavelength-dependent absorption difference as a contrast mechanism to image the target molecule. In this paper, we present a novel multispectral pulsed fiber laser source, which selectively alternates the ...
Sang Min Park, Do Yeon Kim, Soon-Woo Cho, Beop-Min Kim, Tae Geol Lee, Chang-Seok Kim, Sang-Won Lee   +6 more
doaj   +1 more source

Mitigation of artifacts due to isolated acoustic heterogeneities in photoacoustic computed tomography using a variable data truncation-based reconstruction method [PDF]

, 2017
Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue.
Anastasio, Mark A., Li, Lei, Matthews, Thomas P., Poudel, Joemini, Wang, Lihong V.   +4 more
core   +2 more sources

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Continuous-wave photoacoustic microscopy [PDF]

SPIE Proceedings, 2007
We have built a photoacoustic microscope (PAM) using an amplitude-modulated continuous-wave (CW) laser source, which is an inexpensive 120-mW laser diode. By using a bowl-shaped piezoelectric transducer, whose numerical aperture is 0.85 and resonance frequency is 2.45 MHz, we have experimentally demonstrated a lateral resolution of 600 mm, an axial ...
Maslov, Konstantin, Wang, Lihong V.
openaire   +2 more sources

Real‐Time In Vivo Visualization of Tumor‐Associated Macrophage Reprogramming Using a Nitric Oxide‐Activatable NIR‐II Nanoinducer

Advanced Science, EarlyView.
Reprogramming tumor‐associated macrophages is a promising therapeutic strategy for solid tumors. Here, a nitric oxide (NO)‐activatable NIR‐II fluorescence/photoacoustic nanoinducer (I/E@M2pep) that simultaneously facilitates and visualizes the repolarization of TAMs to an M1‐like phenotype is reported, thereby enhancing anti‐tumor efficacy through M1 ...
Qian Chen, Meng Li, Tuanwei Li, Chen Yang, Xiaohu Yang, Hongchao Yang, Yejun Zhang, Chunyan Li, Qiangbin Wang   +8 more
wiley   +1 more source