Results 81 to 90 of about 10,844 (210)

Functional photoacoustic microscopy [PDF]

, 2009
This dissertation focuses on laser-based noninvasive photoacoustic microscopy of subsurface structures in vivo. Photoacoustic microscopy is a hybrid imaging modality that combines the high-resolution advantage of ultrasonic imaging in deep tissue with ...
Zhang, Hao
core  

Synergistic Probe Combining Lysosome Anchoring and Tumor Defense System Targeting for Precise Tumor Visualization

Advanced Science, EarlyView.
A new generation of high‐precision fluorescent probes based on the lysosomal characteristics in tumor metabolic reprogramming and overexpressed tumor markers. The probe (CN‐D‐GGT) selectively label cancer cells in co‐culture systems and distinguish tumor lesions from inflamedand normal tissues in vivo, enabling precise tumor imaging.
Yang Shen, Jiawei Li, Ruixi Yi, Ling Shi, Wei Li, Sulai Liu, Lin Yuan   +6 more
wiley   +1 more source

Single Element-Based Dual Focused Photoacoustic Microscopy

Photonics, 2015
We present a single element-based dual focused photoacoustic microscopy (PAM) that shows improved signal-to-noise ratio and lateral resolution compared to conventional single focused PAM in the out-of-focus region.
Jianbo Tang, Huabei Jiang
doaj   +1 more source

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

Advanced Intelligent Discovery, EarlyView.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu, Rujia Liu, Xinyan Zhang, Xun Chen, Shuhua Yue   +4 more
wiley   +1 more source

Laser Photoacoustic Microscopy

The Review of Laser Engineering, 1983
We have performed photoacoustic micro-imaging using a microphone detection technique. A microcomputer controlled photoacoustic imaging system is developed. A sample on a sensitive photoacoustic cell is scanned mechanically and photoacoustic signals generated by a focused laser beam are detected with a condenser microphone and a lock-in amplifier.
YATAGAI, Toyohiko, ITOH, Masahide, HINO, Makoto, TAKAHASHI, Ichirou, SAITO, Hiroyoshi, KIM, Pil Hyon, NAMBA, Susumu   +6 more
openaire   +2 more sources

Unsupervised inter-domain transformation for virtually stained high-resolution mid-infrared photoacoustic microscopy using explainable deep learning

Nature Communications
Mid-infrared photoacoustic microscopy can capture biochemical information without staining. However, the long mid-infrared optical wavelengths make the spatial resolution of photoacoustic microscopy significantly poorer than that of conventional confocal
Eunwoo Park, Sampa Misra, Dong Gyu Hwang, Chiho Yoon, Joongho Ahn, Donggyu Kim, Jinah Jang, Chulhong Kim   +7 more
doaj   +1 more source

Multi-scale molecular photoacoustic tomography of gene expression.

PLoS ONE, 2012
Photoacoustic tomography (PAT) is a molecular imaging technology. Unlike conventional reporter gene imaging, which is usually based on fluorescence, photoacoustic reporter gene imaging relies only on optical absorption. This work demonstrates several key
Xin Cai, Li Li, Arie Krumholz, Zijian Guo, Todd N Erpelding, Chi Zhang, Yu Zhang, Younan Xia, Lihong V Wang   +8 more
doaj   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

A review of clinical photoacoustic imaging: Current and future trends

Photoacoustics, 2019
Photoacoustic imaging (or optoacoustic imaging) is an upcoming biomedical imaging modality availing the benefits of optical resolution and acoustic depth of penetration. With its capacity to offer structural, functional, molecular and kinetic information
Amalina Binte Ebrahim Attia, Ghayathri Balasundaram, Mohesh Moothanchery, U.S. Dinish, Renzhe Bi, Vasilis Ntziachristos, Malini Olivo   +6 more
doaj   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source