Results 61 to 70 of about 8,074 (200)

Unravelling polyphenol skin permeation: A comparative study using full‐thickness 3D in vitro and ex vivo human skin models

International Journal of Cosmetic Science, EarlyView.
This study demonstrates that full‐thickness 3D in vitro skin models reliably assess the permeation of cosmetic polyphenols, revealing compound‐specific transport profiles and bridging the gap between conventional cell models and ex vivo human skin, while offering an ethical and robust alternative for dermal absorption screening. Abstract The evaluation
Mariana Marques, Filipa Teixeira, Mónica Vieira, M. Helena Amaral, Paulo C. Costa, Stefano Dall'Acqua, Francisca Rodrigues   +6 more
wiley   +1 more source

Peptide CyRL-QN15 alleviates UVB-induced skin aging by promoting the repair of barrier

Ecotoxicology and Environmental Safety
Skin photoaging, a process with substantial physical and psychological impacts, is also a recognized risk factor for skin cancer. Despite advancements in dermatological research, effective prevention and reversal of photoaging remain challenging.
Zijian Kang, Saige Yin, Xiaoya Han, Xin Liu, Ying Peng, Qiuye Jia, Zhe Fu, Yuansheng Li, Yutong Wu, Zhaoxun Xiao, Zhiruo Li, Ying Wang, Mingying Luo, Xinwang Yang   +13 more
doaj   +1 more source

Protective effects of extracellular vesicle‐like nanoparticles derived from Cannabis sativa adventitious roots against UVB‐induced damage in human keratinocytes

International Journal of Cosmetic Science, EarlyView.
Cannabis sativa root‐derived extracellular vesicle‐like nanoparticles (CA‐NPs) were isolated from adventitious root cultures and subjected to physicochemical characterization. Upon UVB exposure, keratinocytes exhibited increased ROS generation, apoptosis and MAPK activation, leading to oxidative stress and skin damage.
Dong Ho Bak, Su Hyun Park, Young Bae Ryu, Cha Young Kim, Jae Cheol Jeong, Woo Sik Kim   +5 more
wiley   +1 more source

Curcumin: a potential anti-photoaging agent

Frontiers in Pharmacology
Turmeric, also referred to as Curcuma longa, is a commonly used spice, recognized for its demonstrated effects in reducing inflammation, combating microbes, providing antioxidant benefits, slowing the aging process, and exhibiting anticancer potential ...
Yuhong Nie, Yiming Li
doaj   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Enhancing Transdermal Delivery: The Role of Gecko-Derived Cathelicidin Peptide G3CY-10 in UV-Induced Skin Photoaging

Biomolecules
Ultraviolet (UV) radiation-induced skin photoaging impacts both appearance and skin health, potentially leading to disorders and cancer. Unlike traditional sunscreens, natural antioxidants can target photoaging at its source.
Yunjiao Wang, Zicheng Ma, Fengshuo Li, Xuanzeng Li, Ningyang Gao, Junhan Wang, Shasha Cai   +6 more
doaj   +1 more source

Identification of A Novel Antioxidant Tripeptide Ameliorating Skin Photoaging [PDF]

J Cosmet Dermatol
ABSTRACT Background Skin photodamage induced by ultraviolet (UV) exposure is the primary factor of photoaging, and developing bioactive molecules targeting this process represents a key focus in dermatology and cosmetic biotechnology. However, a comprehensive screening strategy combining combinatorial library construction with multi‐target validation ...
Lu J, Li J, wang L, Xia L, Wan Y, Li Q.
europepmc   +2 more sources

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson, Catalina Silva‐Hirschberg, Liliana Freeland, Kristen L. Chen, Nagore I. Marín‐Ramos, Axel H. Schönthal, Thomas C. Chen   +6 more
wiley   +1 more source

Exploring natural sunscreens: UVB protection and antioxidant properties in gadusol‐rich fish roes extracts

Photochemistry and Photobiology, EarlyView.
Gadusol‐rich extracts provide effective UVB protection and antioxidant activity in HaCaT cells and C. elegans, highlighting their potential as natural photochemoprotective agents for pharmaceutical and cosmetic applications. It also demonstrates remarkable in vitro antioxidant capacity and thermal stability over time.
Rocío Isla Naveira, Gabriela Hollmann, José María Monserrat, Ana Paula S. Votto, Julie Medeiros da Silveira, Andressa Mai Matsumoto, Lais Zortéa, Andy Joel Taipe Huisa, Agueda E. Massa, M. Sandra Churio   +9 more
wiley   +1 more source

How to Prevent Photoaging? [PDF]

Journal of Investigative Dermatology, 2005
There are several theories on photoaging and its etiology. At this time, however, the only defenses commonly believed to prevent photoaging are the use of sunscreens to reduce the amount of ultraviolet (UV) that reaches the skin, the use of retinoids to prevent production of collagenase and stimulate collagen production, and the use of antioxidants to ...
openaire   +2 more sources