Results 61 to 70 of about 23,948 (255)

Allergen Content of Inactive Ingredients in Best‐Selling Sunscreens: A Comparison of Key Product Features

open access: yesContact Dermatitis, EarlyView.
Allergenic risk of sunscreen active ingredients is well known, but that of inactive ingredients remains understudied. We identified and quantified allergens found in inactive ingredients of best‐selling sunscreens and developed a free tool (www.NAC80.com) that helps dermatologists recognise higher‐risk products and counsel patients prone to allergic or
Emily J. Levin   +4 more
wiley   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

open access: yesThe FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Skin Changes in the Elderly People – How Strong is the Influence of the UV Radiation on Skin Aging? [PDF]

open access: yes, 2010
Just like every other part of the organism, the skin ages as a result of the passage of time. That process is called chronologic or intrinsic aging. However, skin is also exposed to external insults, such as UV radiation, which is the most influential ...
Ivan Krolo   +5 more
core   +1 more source

Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice [PDF]

open access: yes, 2018
Microalgae represent a source of bio-active compounds such as carotenoids with potent anti-inflammatory and antioxidant properties. We aimed to investigate the effects of fucoxanthin (FX) in both in vitro and in vivo skin models.
Cózar Bernal, María José   +6 more
core   +1 more source

UVB-mediated DNA damage induces matrix metalloproteinases to promote photoaging in an AhR- and SP1-dependent manner

open access: yesJCI Insight, 2022
It is currently thought that UVB radiation drives photoaging of the skin primarily by generating ROS. In this model, ROS purportedly activates activator protein-1 to upregulate MMPs 1, 3, and 9, which then degrade collagen and other extracellular matrix ...
Daniel J. Kim   +3 more
semanticscholar   +1 more source

3D Monte Carlo radiation transfer modelling of photodynamic therapy [PDF]

open access: yes, 2015
We acknowledge the support of the UK Engineering and Physics Sciences Research Council (EPSRC) for funding through a studentship for C L Campbell as well as the Alfred Stewart Trust.The effects of ageing and skin type on Photodynamic Therapy (PDT) for ...
Brown, C Tom A   +5 more
core   +1 more source

An update on the landscape of collagen bioactive fragments

open access: yesThe FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Antioxidants in Photoaging: From Molecular Insights to Clinical Applications

open access: yesInternational Journal of Molecular Sciences
Photoaging (PA) is considered a silent disease affecting millions of people globally and is defined as skin damage due to prolonged exposure to ultraviolet radiation (UVR) from the sun.
María J. Calvo   +8 more
semanticscholar   +1 more source

Sunscreens and Photoaging: A Review of Current Literature

open access: yesAmerican Journal of Clinical Dermatology, 2021
Sunscreens have been on the market for many decades as a means of protection against ultraviolet-induced erythema. Over the years, evidence has also shown their efficacy in the prevention of photoaging, dyspigmentation, DNA damage, and ...
L. Guan, H. Lim, T. Mohammad
semanticscholar   +1 more source

Moringia oleifera Lam. seeds isothiocyanate against skin photoaging by regulating p38 MAPK-dependent autophagy signalling pathway

open access: yesFood Science and Human Wellness
People living long-term in areas with UV will cause premature photoaging. An abnormal reduction in autophagy is a key feature of photoaging, and p38 MAPK has been regarded as a key regulator of autophagy.
Min Yang   +9 more
doaj   +1 more source

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