Results 111 to 120 of about 53,053 (260)

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

Advanced Science, EarlyView.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic, Zachary M. Geisterfer, Akshita Chhabra, Vladimir M. Jovanovic, Ian Seim, Christian Hoffmann, Antonela Condric, Gerard Aguilar Pérez, Rinse de Boer, Lars T. Hofstede, Jingao Sun, Kiara Freitag, Katja Nowick, Marina Jendrach, Frank L. Heppner, Vladimir Despic, Michaela Müller‐McNicoll, Stephan Sigrist, Geert van den Bogaart, Sofiia Reshetniak, Amy S. Gladfelter, Dragomir Milovanovic   +21 more
wiley   +1 more source

Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation

Advanced Science, EarlyView.
Using a newly developed Droplet Interface Bilayer‐Pipette assay, the authors show that two segments of the CyaA toxin cross membranes by distinct mechanisms. One segment translocates spontaneously, whereas the translocation of the other depends on membrane potential.
Gaia Scilironi, Nicolas Carvalho, Jacinthe Frangieh, Corentin Léger, Dorothée Raoux‐Barbot, J. Iñaki Guijarro, Daniel Ladant, Sophie Cribier, Nicolas Rodriguez, Alexandre Chenal   +9 more
wiley   +1 more source

Photobleaching of Imidazole Brown Carbon in Single Levitated Aerosol Particles. [PDF]

J Phys Chem A
Zhang X, Meehan PE, Knight JW, Orr-Ewing AJ, Cotterell MI.   +4 more
europepmc   +1 more source

Photocatalytic Recovery of Aromatic Chemicals from Waste Plastics

Advanced Science, EarlyView.
This Review summarizes recent advances in the photocatalytic recovery of aromatic chemicals from plastic waste, with emphasis on fundamental mechanism, representative catalytic systems, and future challenges and development directions, which is expected to provide in‐depth and valuable insights and references into the key role of sustainable catalysis ...
Lizhen Liu, Jutarat Jitrada, Jun Huang
wiley   +1 more source

Accessibility of telomeric overhangs to stabilizing small-molecule ligands. [PDF]

Nucleic Acids Res
Alfehaid J, Surasinghe V, Kodikara SG, Kabir ML, Shiekh S, Tera M, Nagasawa K, Portman JJ, Balci H.   +8 more
europepmc   +1 more source

Responsive Membrane Antenna Enables Adaptive Biohybrid Interface for Photosynthesis Promotion, Stress Reporting and Modulation

Advanced Science, EarlyView.
An environmentally responsive antenna assembled onto the algal cell membrane creates a biohybrid with a responsive interface that promotes photosynthesis under normal conditions and shifts to H2O2‐triggered stress reporting and modulation upon stress onset, boosting environmental sensing and adaptive response.
Bing Liu, Gongmeiyue Su, Jingyi Shi, Hang Yao, Yuchun Han, Zhao Li, Chengcheng Zhou   +6 more
wiley   +1 more source

Photobleaching-based autofluorescence mapping reveals distinct patterns in sporadic basal cell carcinoma, nevoid basal cell carcinoma syndrome-associated basal cell carcinoma and squamous cell carcinoma. [PDF]

Front Med (Lausanne)
Plorina EV, Lihacova I, Boostani M, Bozsányi S, Kiss N, Bliznuks D, Skrastina M, Lihachev A.   +7 more
europepmc   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

A Standardized Prism-Based TIRF Platform for Quantitative Single-Molecule Fluorescence Studies of Biomolecular Dynamics. [PDF]

Biosensors (Basel)
Patra A, Melton L, Sawyer LS, King T, Ray S.   +4 more
europepmc   +1 more source

RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites

Advanced Science, EarlyView.
At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo, Yonghyeon Kim, Nangyeong Hwang, Gwanho Sung, Sujin Jo, Yeonhu Lee, Ho‐Chul Kang, Jae‐Ho Lee, Yong Won Choi, Hyeseong Cho, Sunwoo Min   +10 more
wiley   +1 more source