Results 201 to 210 of about 110,959 (369)

ADA2 Forms Nuclear Condensates with GCN5 and ATP‐Citrate Lyase (ACL) to Modulate H3K9 Acetylation at Genes Functioning in Rice Meristems

Advanced Science, EarlyView.
This study unveils a novel GAA (GCN5‐ADA2‐ACL) complex that forms nuclear condensates to boost local acetyl‐CoA, facilitating histone acetylation and gene transcription in rice meristems. The research underscores the role of ADA2's disordered region in complex condensation and ACL's role in acetyl‐CoA production.
Yaping Yue, Tingting Lu, Xiaoyuan Guo, Biao Liu, Shiteng Lv, Heba A. M. Abdalla, Xuelei Lai, Ruihui Zhang, Jianpin Guo, Yu Zhao, Dao‐Xiu Zhou, Shaoli Zhou   +11 more
wiley   +1 more source

Imaging protoporphyrin IX photoproduct accumulation as a dosimetry reporter for monitoring photodynamic therapy of oral cancer. [PDF]

J Biomed Opt
Liboy C, Khan S, Song B, Vega D, Saad MA, Liang R, Hasan T, Celli JP.   +7 more
europepmc   +1 more source

Flash Photodynamic Therapy – How the Saturation of Photosensitizer Absorption Enables Selective and Deeper Tumor Treatments

Advanced Science, EarlyView.
FLASH‐PDT uses strongly‐absorbing photosensitizers and pulsed lasers to saturate the photosensitizer absorption at ≈1‐cm tissue depths. This allows for the generation of [ROS] above the necrosis threshold level for tumors, while maintaining [ROS] in peritumoral tissues below that threshold, even when the tumor‐to‐peritumoral tissue ratio is as low as 2.
Luis G. Arnaut, Fábio A. Schaberle, José Sereno, Lígia C. Gomes‐da‐Silva   +3 more
wiley   +1 more source

PolyQ Expansion Controls Biomolecular Condensation and Aggregation of the N-Terminal Fragments of Ataxin-2. [PDF]

Int J Mol Sci
Liu YH, Duan HT, Jiang LL, Hu HY.
europepmc   +1 more source

Disordered Glass Nanowire Substrates Produce in Vivo‐Like Astrocyte Morphology Revealed by Low‐Coherence Holotomography

Advanced Science, EarlyView.
Low‐coherence holotomography reveals that disordered nanowire substrates guide astrocyte morphology toward branched, in vivo–like star‐shaped morphology, emphasizing the role of biophysical cues in shaping neural cell behavior. The developed nanostructured platform offers a new route to study astrocytes for neurobiology studies. Abstract Astrocytes are
Pooja Anantha, Anoushka Gupta, Joo Ho Kim, Emanuela Saracino, Piyush Raj, Ivano Lucarini, Swati Tanwar, Jessica Chen, Luo Gu, Jay Agrawal, Annalisa Convertino, Ishan Barman   +11 more
wiley   +1 more source

Human liver and pancreas innervation: resolving 3D neurohistological challenges and advancing insights. [PDF]

J Biomed Sci
Lee CY, Hsiao FT, Chen CC, Tang SC.
europepmc   +1 more source

LITE microscopy: Tilted light-sheet excitation of model organisms offers high resolution and low photobleaching [PDF]

, 2018
Tanner Fadero, Therese M. Gerbich, Kishan Rana, Aussie Suzuki, Matthew DiSalvo, Kristina N. Schaefer, Jennifer K. Heppert, Thomas E. Boothby, Bob Goldstein, Mark Peifer, Nancy L. Allbritton, Amy S. Gladfelter, Amy Shaub Maddox, Paul S. Maddox   +13 more
openalex   +1 more source

Axial superresolution via multiangle TIRF microscopy with sequential imaging and photobleaching

Proceedings of the National Academy of Sciences of the United States of America, 2016
YAN-ZHE Fu, Peter W. Winter, R. Rojas, Victor Wang, M. McAuliffe, G. Patterson   +5 more
semanticscholar   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

The Combined Photosensitizers in Antimicrobial Photodynamic Therapy: The Case of Methylene Blue and Photodithazine Against <i>Klebsiella pneumoniae</i>. [PDF]

Int J Mol Sci
Yerra KR, Soares JM, Bagnato VS.
europepmc   +1 more source