Results 131 to 140 of about 17,338 (213)

Depth of DNA photodamage in human corneas exposed to 222 nm or 254 nm UV

Photochemistry and Photobiology, EarlyView.
Representative confocal 3D image of a section of a human cornea showing nuclei in blue (Hoechst 33342) and green, which was assigned to cells exhibiting Alexa555 conjugated to anti‐CPD antibody. The depth of photodamage was measured in Z‐stacks of the human corneal epithelium after exposure of the anterior surface to 50 or 100 mJ/cm2 at 222 or 254 nm ...
Manuela Buonanno, Istvan R. Boldogh, Raabia Hashmi, Camryn Petersen, David Welch, Theresa C. Swayne, David J. Brenner   +6 more
wiley   +1 more source

Klotho Protein as a Topical Therapy for Facial Photoaging Using Combined Delivery Technologies. [PDF]

Plast Reconstr Surg Glob Open
Yoelin SG, Xu M, Lam JC, Harrington GL, Humble GM.   +4 more
europepmc   +1 more source

Super-sensitive chemical imaging by high energy low photodamage Coherent Anti-stokes Raman Scattering (HELP-CARS)

We introduce a high-energy, low-photodamage CARS (HELP-CARS) imaging platform using high-energy extensively chirped excitation pulse to enable bio-imaging with micromolar sensitivity.
Guangrui Ding, Ji-Xin Cheng
core   +1 more source

Platelet‐activating factor‐receptor signaling mediates solar‐simulated light‐induced extracellular vesicle release in human keratinocytes

Photochemistry and Photobiology, EarlyView.
Solar‐simulated light (SSL) promotes extracellular vesicle (EV) release from keratinocytes through a UVB‐driven, oxidative stress‐dependent pathway. SSL‐induced reactive oxygen species (ROS) generate oxidized glycerophosphocholines with PAF agonistic activity, which activate the Platelet‐activating factor receptor (PAFR), leading to acid ...
Divyanshu Aggarwal, Anita Thyagarajan, Michael G. Kemp, Ravi P. Sahu   +3 more
wiley   +1 more source

Revisiting the action spectrum of DNA damage: Chemiexcitation and the expanded biological spectrum of cyclobutane pyrimidine dimer formation

Photochemistry and Photobiology, EarlyView.
UVB and UVA generate cyclobutane pyrimidine dimers (CPDs) during irradiation (purple). After exposure ends, chemiexcitation in pigmented melanocytes continues to generate delayed CPDs (yellow), even as repair removes some pre‐existing lesions. Consequently, total CPD burden can rise while visible erythema fades.
Jyoti Srivastava, Marcus S. Cooke, Sanjay Premi   +2 more
wiley   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Author Correction: B7-H3 promotes skin photodamage through ITGA2-NRF2-TFAM-mediated mitochondrial oxidative stress. [PDF]

Commun Biol
Jia Y, Zhang Q, Su F, Zhu Y, Chen S, Yang J, Mao Q, Zhang Y, Yang Y, Ding S, Liu C, Zhang X, Luo D, Min W, Cao L.   +14 more
europepmc   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Predicting the Risk of Proteinuria Based on Blood Plasma Fourier‐Transform Infrared Spectroscopy and Machine Learning Algorithms From Pregnant Women and Newborns

Analytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT Proteinuria, defined by an abnormally elevated concentration of proteins in the urine, serves as a critical biomarker for the early detection and diagnosis of preeclampsia. Elevated proteinuria levels adversely affect both maternal and foetal health, increasing the risk of preterm birth and low birth weight.
Camila Lopes Ferreira, Sara Maria Santos Dias da Silva, Luma Martins Aleixo de Oliveira, Vitórya Carvalho Pádua de Magalhães, Simone Lima Silva, Sheila Cavalca Cortelli, Rodrigo Augusto Silva, Jaqueline Maria Brandão Rizzato, Marcelo Saito Nogueira, Luís Felipe Das Chagas e Silva de Carvalho   +9 more
wiley   +1 more source

Neutrophil Extracellular Traps Exacerbate UVB-Induced Photodamage in HaCaT Cells and Mouse Skin via CCDC25/MAPK Pathway. [PDF]

Aging Cell
Zou Y, Li J, Peng Y, Hu R, Li R, Chen A.
europepmc   +1 more source