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The photodynamic and non-photodynamic actions of porphyrins [PDF]
Brazilian Journal of Medical and Biological Research, 1999 Porphyrias are a family of inherited diseases, each associated with a partial defect in one of the enzymes of the heme biosynthetic pathway. In six of the eight porphyrias described, the main clinical manifestation is skin photosensitivity brought about ...
S.G. Afonso +2 more
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Biomedicines, 2022 In 1903, Von Tappeiner and Jesionek [...]
Kyungsu Kang, Stefano Bacci
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Drug Delivery, 2022 Thrombosis occurs in both macrovasculature and microvasculature, causing various cardio-cerebral vascular diseases. The lack of effective and safe antithrombotic drugs leads to a public health crisis.
Dan Chen +6 more
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Scientific Reports, 2021 Cancer can develop into a recurrent metastatic disease with latency periods of years to decades. Dormant cancer cells, which represent a major cause of recurrent cancer, are relatively insensitive to most chemotherapeutic drugs and radiation.
Taku Nakayama +8 more
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Accelerating skin regeneration and wound healing by controlled ROS from photodynamic treatment
Inflammation and Regeneration, 2022 Cellular metabolisms produce reactive oxygen species (ROS) which are essential for cellular signaling pathways and physiological functions. Nevertheless, ROS act as “double-edged swords” that have an unstable redox balance between ROS production and ...
Khatereh Khorsandi +5 more
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Biomedicines, 2022 We have previously shown that a radioactive (123I)-analog of methyl 3-(1′-(iodobexyloxy) ethyl-3-devinylpyropheophorbide-a (PET-ONCO), derived from chlorophyll-a can be used for positron emission tomography (PET) imaging of a variety of tumors, including
Joseph C. Cacaccio +3 more
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Nanomaterial-based photodynamic therapy for antibacterial applications: a comprehensive review
Frontiers in Materials, 2023 Microbial infections continue to pose a significant health challenge, especially with an increase in drug-resistant bacteria. Conventional antibiotic treatments show limited efficacy, prompting researchers to explore alternative treatments.
Yujie Gao +6 more
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JNCI Journal of the National Cancer Institute, 1998 Photodynamic therapy involves administration of a tumor-localizing photosensitizing agent, which may require metabolic synthesis (i.e., a prodrug), followed by activation of the agent by light of a specific wavelength. This therapy results in a sequence of photochemical and photobiologic processes that cause irreversible photodamage to tumor tissues ...
T J, Dougherty +7 more
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Immunomodulatory Effects by Photodynamic Treatment of Glioblastoma Cells In Vitro
Molecules, 2022 Multimodal treatment adding immunotherapy and photodynamic treatment (PDT) to standard therapy might improve the devastating therapeutic outcome of glioblastoma multiforme patients.
Friederike Rothe +3 more
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A Transcriptomic Approach to the Metabolism of Tetrapyrrolic Photosensitizers in a Marine Annelid
Molecules, 2021 The past decade has seen growing interest in marine natural pigments for biotechnological applications. One of the most abundant classes of biological pigments is the tetrapyrroles, which are prized targets due their photodynamic properties; porphyrins ...
Maria Leonor Santos +4 more
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