Results 11 to 20 of about 91,005 (304)
The photodynamic and non-photodynamic actions of porphyrins [PDF]
Brazilian Journal of Medical and Biological Research, 1999 Porphyrias are a family of inherited diseases, each associated with a partial defect in one of the enzymes of the heme biosynthetic pathway. In six of the eight porphyrias described, the main clinical manifestation is skin photosensitivity brought about ...
S.G. Afonso +2 more
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Drug Delivery, 2022 Thrombosis occurs in both macrovasculature and microvasculature, causing various cardio-cerebral vascular diseases. The lack of effective and safe antithrombotic drugs leads to a public health crisis.
Dan Chen +6 more
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Scientific Reports, 2021 Cancer can develop into a recurrent metastatic disease with latency periods of years to decades. Dormant cancer cells, which represent a major cause of recurrent cancer, are relatively insensitive to most chemotherapeutic drugs and radiation.
Taku Nakayama +8 more
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Accelerating skin regeneration and wound healing by controlled ROS from photodynamic treatment
Inflammation and Regeneration, 2022 Cellular metabolisms produce reactive oxygen species (ROS) which are essential for cellular signaling pathways and physiological functions. Nevertheless, ROS act as “double-edged swords” that have an unstable redox balance between ROS production and ...
Khatereh Khorsandi +5 more
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Biomedicines, 2022 We have previously shown that a radioactive (123I)-analog of methyl 3-(1′-(iodobexyloxy) ethyl-3-devinylpyropheophorbide-a (PET-ONCO), derived from chlorophyll-a can be used for positron emission tomography (PET) imaging of a variety of tumors, including
Joseph C. Cacaccio +3 more
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Frontiers in Bioengineering and Biotechnology, 2021 Melanin, as a natural product, has been used as an extraordinary ingredient for nanomedicine due to its great biocompatibility and light responsive property.
Ding Liu +3 more
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JNCI Journal of the National Cancer Institute, 1998 Photodynamic therapy involves administration of a tumor-localizing photosensitizing agent, which may require metabolic synthesis (i.e., a prodrug), followed by activation of the agent by light of a specific wavelength. This therapy results in a sequence of photochemical and photobiologic processes that cause irreversible photodamage to tumor tissues ...
T J, Dougherty +7 more
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SYNTHESIS OF DYNAMIC RIBOFLAVIN DERIVATIVES AND THE STUDY OF THEIR ABILITY TO UREASE PHOTOINACTIVATION [PDF]
Annals of Mechnikov's Institute, 2019 Introduction. In one patents demonstrated the riboflavin ability to inactivate vaccine strains of viruses and bacteria, as well as cancer cells during the production of vaccines .
Martynov, A.V. +4 more
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Targeted Nanoparticles for Fluorescence Imaging of Folate Receptor Positive Tumors
Biomolecules, 2020 This report presents the synthesis and folate receptor target-specificity of amino-functionalized polyacrylamide nanoparticles (AFPAA NPs) for near-infrared (NIR) fluorescence imaging of cancer. For the synthesis of desired nano-constructs, the AFPAA NPs
Aimee J. Marko +7 more
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Advanced Science, 2023 Glutathione S‐transferase (GST), which is a key enzyme in the conjugation reaction of glutathione (GSH), is overexpressed in cancer cells, leading to cisplatin deactivation and ultimately drug resistance. In addition, many tumors are immune “cold tumors,”
Qinxin Zhao +8 more
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