Results 11 to 20 of about 193,535 (345)
The photodynamic and non-photodynamic actions of porphyrins [PDF]
Brazilian Journal of Medical and Biological Research, 1999 Porphyrias are a family of inherited diseases, each associated with a partial defect in one of the enzymes of the heme biosynthetic pathway. In six of the eight porphyrias described, the main clinical manifestation is skin photosensitivity brought about ...
S.G. Afonso +2 more
doaj +5 more sources
Carrier-Free Stimulus-Responsive Theranostic Nanoprodrug Enabling GSH-Consumption-Promoted Chemo-Photodynamic Cancer Therapy. [PDF]
Adv Sci (Weinh)Leveraging the critical role of glutathione (GSH) in mediating drug resistance and scavenging reactive oxygen species (ROS) in cancer cells, a carrier‐free GSH‐consuming theranostic nanoprodrug, consisting of a BODIPY photosensitizer and the chemotherapeutic drug paclitaxel linked through a GSH‐consuming drug linker, is developed to deeply explore the ...
Huang H, Sui B.
europepmc +2 more sources
JNCI Journal of the National Cancer Institute, 1998 Photodynamic therapy involves administration of a tumor-localizing photosensitizing agent, which may require metabolic synthesis (i.e., a prodrug), followed by activation of the agent by light of a specific wavelength. This therapy results in a sequence of photochemical and photobiologic processes that cause irreversible photodamage to tumor tissues ...
T J, Dougherty +7 more
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A Transcriptomic Approach to the Metabolism of Tetrapyrrolic Photosensitizers in a Marine Annelid
Molecules, 2021 The past decade has seen growing interest in marine natural pigments for biotechnological applications. One of the most abundant classes of biological pigments is the tetrapyrroles, which are prized targets due their photodynamic properties; porphyrins ...
Maria Leonor Santos +4 more
doaj +1 more source
Nanomaterials for the treatment of bacterial infection by photothermal/photodynamic synergism
Frontiers in Bioengineering and Biotechnology, 2023 In the past few decades, great progress has been made in the field of nanomaterials against bacterial infection. However, with the widespread emergence of drug-resistant bacteria, people try their best to explore and develop new antibacterial strategies ...
Zhaochen Yan, Danqiu Wang, Yun Gao
doaj +1 more source
Photodynamic Therapy Review: Principles, Photosensitizers, Applications, and Future Directions
Pharmaceutics, 2021 Photodynamic therapy (PDT) is a minimally invasive therapeutic modality that has gained great attention in the past years as a new therapy for cancer treatment.
J. H. Correia +4 more
semanticscholar +1 more source
Targeted Nanoparticles for Fluorescence Imaging of Folate Receptor Positive Tumors
Biomolecules, 2020 This report presents the synthesis and folate receptor target-specificity of amino-functionalized polyacrylamide nanoparticles (AFPAA NPs) for near-infrared (NIR) fluorescence imaging of cancer. For the synthesis of desired nano-constructs, the AFPAA NPs
Aimee J. Marko +7 more
doaj +1 more source
Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy
Theranostics, 2022 Cancer immunotherapy has made tremendous clinical progress in advanced-stage malignancies. However, patients with various tumors exhibit a low response rate to immunotherapy because of a powerful immunosuppressive tumor microenvironment (TME) and ...
Bin Ji, Min-Jie Wei, Bin Yang
semanticscholar +1 more source
Photodynamic Therapy—Current Limitations and Novel Approaches
Frontiers in Chemistry, 2021 Photodynamic therapy (PDT) mostly relies on the generation of singlet oxygen, via the excitation of a photosensitizer, so that target tumor cells can be destroyed. PDT can be applied in the settings of several malignant diseases.
G. Gunaydin, M. E. Gedik, Seylan Ayan
semanticscholar +1 more source
Biomedicines, 2022 In 1903, Von Tappeiner and Jesionek [...]
Kyungsu Kang, Stefano Bacci
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