Results 1 to 10 of about 130,200 (126)

Photodynamic Therapy Using Topically Applied Dihematoporphyrin Ether in the Treatment of Cervical Intraepithelial Neoplasia [PDF]

open access: yesGynecologic Oncology, 1997
To perform a phase I study of topically applied dihematoporphyrin ether (DHE) in the photodynamic treatment (PDT) of cervical intraepithelial neoplasia (CIN) using fixed DHE doses and application schedules, and a variable dose of 630 nm red light delivered by an argon-pumped dye laser.Between February 1993 and April 1994, 24 nonpregnant women with a ...
Michael Berns   +2 more
exaly   +7 more sources

Drug-induced photosensitivity: culprit drugs, potential mechanisms and clinical consequences. [PDF]

open access: yesJ Dtsch Dermatol Ges, 2021
Summary Drug‐induced photosensitivity, the development of phototoxic or photoallergic reactions due to pharmaceuticals and subsequent exposure to ultraviolet or visible light, is an adverse effect of growing interest. This is illustrated by the broad spectrum of recent investigations on the topic, ranging from molecular mechanisms and culprit drugs ...
Hofmann GA, Weber B.
europepmc   +2 more sources

Successful Treatment of Adult-Onset Recurrent Respiratory Papillomatosis with CO2 Laser and Photodynamic Therapy. [PDF]

open access: yesCase Rep Otolaryngol, 2019
Recurrent respiratory papillomatosis is a noninvasive benign epithelial tumor caused by human papillomavirus. Clinically, it featured rapid growth, multifocus, and frequent recurrence. Though a number of therapies have been investigated, the recurrence after treatment is always a challenge.
Lu S, Liu Y, Shi R, Zhou P, Zhou P.
europepmc   +2 more sources

Photodynamic therapy for cancer: mechanisms, photosensitizers, nanocarriers, and clinical studies. [PDF]

open access: yesMedComm (2020)
We highlight the development and molecular mechanisms underlying the activation of photosensitizers, the challenges of PDT in tumor management, and the advantages of nanocarriers‐based PDT against cancer. Abstract Photodynamic therapy (PDT) is a temporally and spatially precisely controllable, noninvasive, and potentially highly efficient method of ...
Zhao W   +8 more
europepmc   +2 more sources

Chloroaluminum sulfonated phthalocyanine versus dihematoporphyrin ether: Early vascular events in the rat window chamber [PDF]

open access: yesThe Laryngoscope, 1991
AbstractThe development of a simple and well‐tolerated rat window chamber has allowed direct comparison of the vascular effects of two photosensitizers, chloroaluminum sulfonated phthalocyanine (CASP) and dihematoporphyrin ether (DHE).CASP and DHE were given 4 days after the implantation of the window chamber.
S J, Stern   +4 more
openaire   +2 more sources

Malignant Conversion of a Solitary Papilloma in the Distal Trachea: Report of a Case

open access: yesCanadian Respiratory Journal, Volume 15, Issue 7, Page 375-376, 2008., 2008
A solitary papilloma versus the usual multiple lesions of papillomatosis is extremely rare. Even more infrequent is a solitary papilloma of the trachea in an adult patient. In the present report, a case of a solitary papilloma in the distal trachea is presented.
Achilleas Lioulias   +6 more
wiley   +1 more source

Detection of Photofrin Fluorescence From Malignant and Premalignant Lesions in the Bronchus using a Full‐color Endoscopic Fluorescence Imaging System

open access: yesDiagnostic and Therapeutic Endoscopy, Volume 7, Issue 3-4, Page 187-195, 2001., 2001
Study objectives: To detect invisible lung cancer and to determine field of laser radiation during PDT we developed a full‐color fluorescence fiberscopic system. We tested the efficacy of this system in patients with various bronchial malignancies. System design: A fiber‐optic endoscope was attached to a camera box containing a color ICCD camera which ...
Yoshinobu Ohsaki   +10 more
wiley   +1 more source

Photodynamic Therapy for Obstructive Esophageal Malignancies

open access: yesDiagnostic and Therapeutic Endoscopy, Volume 5, Issue 3, Page 167-174, 1999., 1999
Objectives Determine factors affecting survival rates, benefits and complications of patients with obstructive esophageal cancer treated with photodynamic therapy (PDT). Methods From 1982 to January 1998, we used PDT to treat 140 patients with obstructive adeno or squamous carcinoma and evaluated survival up to November 1998.
James S. McCaughan Jr.
wiley   +1 more source

Progress of Photodynamic Therapy in Gastric Cancer

open access: yesDiagnostic and Therapeutic Endoscopy, Volume 5, Issue 3, Page 175-182, 1999., 1999
Progress of photodynamic therapy (PDT) in gastric cancer and the clinical outcome are described in this paper. (1) We included the whole lesion and a 5 mm margin in the field for irradiation. Marking by injection of India‐ink showing the irradiation field was performed beforehand.
Seishiro Mimura   +3 more
wiley   +1 more source

Photodynamic Diagnosis and Treatment for Atherosclerosis by an Endoscopic Approach

open access: yesDiagnostic and Therapeutic Endoscopy, Volume 5, Issue 3, Page 191-195, 1999., 1999
The photosensitizer, mono‐L‐aspartyl chlorin e6 (NPe6), specifically accumulates in the atheromatous plaque. We detected the fluorescence spectra of NPe6 emitted from atheromatous plaques on the descending thoracic aorta by an angioscopic approach using the animal model of atherosclerosis.
Junichi Hayashi   +2 more
wiley   +1 more source

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