Results 11 to 20 of about 359 (135)

Drug-induced photosensitivity: culprit drugs, potential mechanisms and clinical consequences. [PDF]

J Dtsch Dermatol Ges, 2021
Summary Drug‐induced photosensitivity, the development of phototoxic or photoallergic reactions due to pharmaceuticals and subsequent exposure to ultraviolet or visible light, is an adverse effect of growing interest. This is illustrated by the broad spectrum of recent investigations on the topic, ranging from molecular mechanisms and culprit drugs ...
Hofmann GA, Weber B.
europepmc   +2 more sources

Successful Treatment of Adult-Onset Recurrent Respiratory Papillomatosis with CO₂ Laser and Photodynamic Therapy. [PDF]

Case Rep Otolaryngol, 2019
Recurrent respiratory papillomatosis is a noninvasive benign epithelial tumor caused by human papillomavirus. Clinically, it featured rapid growth, multifocus, and frequent recurrence. Though a number of therapies have been investigated, the recurrence after treatment is always a challenge.
Lu S, Liu Y, Shi R, Zhou P, Zhou P.
europepmc   +2 more sources

Photodynamic therapy for cancer: mechanisms, photosensitizers, nanocarriers, and clinical studies. [PDF]

MedComm (2020)
We highlight the development and molecular mechanisms underlying the activation of photosensitizers, the challenges of PDT in tumor management, and the advantages of nanocarriers‐based PDT against cancer. Abstract Photodynamic therapy (PDT) is a temporally and spatially precisely controllable, noninvasive, and potentially highly efficient method of ...
Zhao W, Wang L, Zhang M, Liu Z, Wu C, Pan X, Huang Z, Lu C, Quan G.   +8 more
europepmc   +2 more sources

Detection of Photofrin Fluorescence From Malignant and Premalignant Lesions in the Bronchus using a Full‐color Endoscopic Fluorescence Imaging System

Diagnostic and Therapeutic Endoscopy, Volume 7, Issue 3-4, Page 187-195, 2001., 2001
Study objectives: To detect invisible lung cancer and to determine field of laser radiation during PDT we developed a full‐color fluorescence fiberscopic system. We tested the efficacy of this system in patients with various bronchial malignancies. System design: A fiber‐optic endoscope was attached to a camera box containing a color ICCD camera which ...
Yoshinobu Ohsaki, Kaneyoshi Takeyama, Shoko Nakao, Sachie Tanno, Eri Toyoshima, Kyoko Nakanishi, Yutaka Nishigaki, Toshiyuki Ogasa, Shinobu Osanai, Kenjiro Kikuchi, Susumu Nakajima   +10 more
wiley   +1 more source

Photodynamic Therapy for Obstructive Esophageal Malignancies

Diagnostic and Therapeutic Endoscopy, Volume 5, Issue 3, Page 167-174, 1999., 1999
Objectives Determine factors affecting survival rates, benefits and complications of patients with obstructive esophageal cancer treated with photodynamic therapy (PDT). Methods From 1982 to January 1998, we used PDT to treat 140 patients with obstructive adeno or squamous carcinoma and evaluated survival up to November 1998.
James S. McCaughan Jr.
wiley   +1 more source

Progress of Photodynamic Therapy in Gastric Cancer

Diagnostic and Therapeutic Endoscopy, Volume 5, Issue 3, Page 175-182, 1999., 1999
Progress of photodynamic therapy (PDT) in gastric cancer and the clinical outcome are described in this paper. (1) We included the whole lesion and a 5 mm margin in the field for irradiation. Marking by injection of India‐ink showing the irradiation field was performed beforehand.
Seishiro Mimura, Hiroyuki Narahara, Toru Otani, Shigeru Okuda   +3 more
wiley   +1 more source

Photodynamic Diagnosis and Treatment for Atherosclerosis by an Endoscopic Approach

Diagnostic and Therapeutic Endoscopy, Volume 5, Issue 3, Page 191-195, 1999., 1999
The photosensitizer, mono‐L‐aspartyl chlorin e6 (NPe6), specifically accumulates in the atheromatous plaque. We detected the fluorescence spectra of NPe6 emitted from atheromatous plaques on the descending thoracic aorta by an angioscopic approach using the animal model of atherosclerosis.
Junichi Hayashi, Takashi Saito, Katsuo Aizawa   +2 more
wiley   +1 more source

Cooperative Clinical Trial of Photodynamic Therapy for Early Gastric Cancer With Photofrin Injection® and YAG‐OPO Laser

Diagnostic and Therapeutic Endoscopy, Volume 4, Issue 4, Page 165-171, 1998., 1997
Background and Objective: Photodynamic therapy (PDT) treats malignant tumors using photosensitizers and light. We employed a new pulse laser as the excitation light source for PDT, i.e. an optical parametric oscillator (OPO) system pumped by a Q‐switched Nd:YAG laser, because it provides extremely high peak power.
Seishiro Mimura, Hiroyuki Narahara, Toshio Hirashima, Hisayuki Fukutomi, Akira Nakahara, Hiromasa Kashimura, Hirofumi Matsui, Hiroshi Tanimura, Yugo Nagai, Shigeru Suzuki, Yoko Murata, Kazunari Yoshida, Kaichi Isono, Teruo Kozu, Hiroko Ide, Harubumi Kato   +15 more
wiley   +1 more source

A Clinical Study of Photodynamic Therapy for Superficial Esophageal Carcinoma by YAG‐OPO Laser

Diagnostic and Therapeutic Endoscopy, Volume 4, Issue 4, Page 173-176, 1998., 1997
A cooperative clinical study of photodynamic therapy (PDT) for superficial esophageal carcinoma was conducted at 6 medical institution. PHE (2mg/kg) with high tumor affinity was used as the oncotropic compound. The light source was a pulse wave YAG‐OPO laser with high penetration into the tissue. Irradiation was performed at an energy density of 60–180
Kazunari Yoshida, Shigeru Suzuki, Seishiro Mimura, Hiroyuki Narahara, Hiroshi Tanimura, Yugo Nagai, Kaichi Isono, Teruo Kozu, Hisayuki Fukutomi, Akira Nakahara, Hiromasa Kashimura, Toshio Hirashima, Yoko Murata, Hiroko Ide, Harubumi Kato   +14 more
wiley   +1 more source

Bronchoscopy of Lung Cancer

Diagnostic and Therapeutic Endoscopy, Volume 1, Issue 1, Page 9-18, 1994., 1993
Lung cancer is a leading cancer site in men and women with a high incidence and mortality rate. Most patients are diagnosed when the disease has already spread. An early, detection and immediate and accurate histological or cytological diagnosis are essential for a hopeful outcome.
R. W. Hauck, H. P. Emslander
wiley   +1 more source