Results 121 to 130 of about 3,934,990 (326)

Fluorescence diagnosis of metastatic lymph nodes using 5-aminolevulinic acid (5-ALA) in a mouse model of colon cancer. [PDF]

, 2012
[Background]Lymph node metastasis is one of the most critical prognostic factors in patients with colorectal cancer. Although regional lymph nodes should be surgically resected and pathologically examined, techniques for the intraoperative diagnosis of ...
Hasegawa, Suguru, Kato, Shigeru, Kawada, Kenji, Kawamura, Junichiro, Sakai, Yoshiharu   +4 more
core   +1 more source

STING Agonist‐Modified Tumor Targeting Photosensitizer Remodels Cancer‐Associated Fibroblasts to Potentiate Photoimmunotherapy in Pancreatic Cancer

Advanced Science, EarlyView.
This carrier‐free, esterase‐responsive nanoaggregate integrates a mitochondria‐targeting photosensitizer with a non‐nucleotide STING agonist to achieve localized photoactivation and immune reprogramming. ICyM2 remodels tumor stroma, induces potent immunogenic cell death, and triggers intratumoral STING activation, collectively revitalizing the ...
Yixuan Zhang, Shankun Yao, Yihan Zhao, Saisai Zhu, Wen Fang, Ranran Yu, Naiwen Shi, Ruixin Zhang, Yin Zhang, Jiawei Liang, Ziying Zhang, Shijin Xu, Ziwei Zhang, Jiajun Zhang, Yukun Li, Xiaoxuan Han, Yuncong Chen, Shu Zhang, Ying Lv   +18 more
wiley   +1 more source

Simultaneous Photodiagnosis and Photodynamic Treatment of Metastatic Melanoma

Molecules, 2019
Metastatic melanoma (MM) has a poor prognosis and is attributed to late diagnoses only when metastases has already occurred. Thus, early diagnosis is crucial to improve its overall treatment efficacy.
Channay Naidoo, Cherie Ann Kruger, Heidi Abrahamse   +2 more
doaj   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

A glance at imaging bladder cancer. [PDF]

, 2018
Purpose: Early and accurate diagnosis of Bladder cancer (BCa) will contribute extensively to the management of the disease. The purpose of this review was to briefly describe the conventional imaging methods and other novel imaging modalities used for ...
Halpern, Ethan J., Kim, Sung, Salmanoglu, Ebru, Thakur, Mathew L., Trabulsi, Edouard J.   +4 more
core   +1 more source

Cutis verticis gyrata in a patient with multiple basal cell carcinomas; case presentation and review of the literature [PDF]

, 2016
Cutis verticis gyrata is a rare disease characterized by convoluted folds and deep furrows of the scalp, resembling the gyri and sulci of the cerebral cortex.
Benea, Vasile, Georgescu, Simona Roxana, Mitran, Cristina Iulia, Mitran, Mădălina Irina, Rusu, Alice, Sârbu, Maria Isabela, Tampa, Mircea   +6 more
core   +4 more sources

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

Advanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen, Xinglin Chen, Zhenhao Gao, Meng Sun, Yaozong Yu, Fang Lv, Qiujun Wang, Jinfeng Zhang   +7 more
wiley   +1 more source

Photodynamic Therapy Based on Graphene and MXene in Cancer Theranostics

Frontiers in Bioengineering and Biotechnology, 2019
Cancer is one of the leading causes of death in the world. Therefore, the development of new advanced and targeted strategies in cancer research for early diagnosis and treatment has become essential to improve diagnosis outcomes and reduce therapy side ...
Arianna Gazzi, Arianna Gazzi, Laura Fusco, Laura Fusco, Laura Fusco, Anooshay Khan, Davide Bedognetti, Barbara Zavan, Barbara Zavan, Flavia Vitale, Flavia Vitale, Acelya Yilmazer, Acelya Yilmazer, Lucia Gemma Delogu, Lucia Gemma Delogu   +14 more
doaj   +1 more source

Monitoring the accumulation and dissipation of the photosensitizer protoporphyrin IX during standard dermatological methyl-aminolevulinate photodynamic therapy utilizing non-invasive fluorescence imaging and quantification [PDF]

, 2016
Author's post-print is subject to a Creative Commons Attribution Non-Commercial No Derivatives LicenseBACKGROUND: Dermatological methyl-aminolevulinate photodynamic therapy (MAL-PDT) is utilized to successfully treat dermatological conditions. This study
Campbell, Sandra M., Curnow, Alison, Tyrrell, Jessica S.   +2 more
core   +1 more source

Photodynamic diagnosis (PDD) and photodynamic therapy (PDT) in dermatology: “How we do it”

Photodiagnosis and Photodynamic Therapy, 2006
In dermatology PDT has been proven to be effective in the treatment of actinic keratoses, basal cell carcinomas (BCC), Bowen's disease, superficial squamous cell carcinomas (SCC).
A, Sieroń, A, Kawczyk-Krupka, M, Adamek, W, Cebula, W, Zieleźnik, K, Niepsuj, G, Niepsuj, A, Pietrusa, M, Szyguła, T, Biniszkiewicz, S, Mazur, J, Małyszek, A, Romańczyk, A, Ledwoń, A, Frankiewicz, A, Zybura, E, Koczy, B, Birkner   +17 more
openaire   +2 more sources